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Best Joint Pain Products – Learn The Science Behind Joint Pain Supplements That Work!

Learn about popular supplements for arthritis. Read the facts about the best over the counter joint pain supplements and how they may help with symptoms.

best joint pain supplement

The best supplements for joint pain and inflammation. Photo (Pixabay)

*Note– Each product we feature has been independently selected and reviewed by our editorial team. If you buy something through a link on this page, we may earn a small commission. How this works.

What Can I Do For My Joint Pain?

Young individuals enjoy great joint flexibility. Their joints are much more resilient to damage and if injured, typically recover more quickly as compared to joints in older adults.

As we age, muscle tone declines, joints lose lubrication, arthritis may develop, and pain, stiffness, and inflammation become daily issues and are all reasons for the loss in mobility.

Arthritis[1] affects more than one-third of the U.S. population and is a primary cause of disability for adults. There are various types of arthritis, but osteoarthritis is the most common and there is no cure.

“Chronic pain caused by arthritis affects millions of people in the United States every year. About one in four adults with arthritis—15 million people—report experiencing severe joint pain related to arthritis”, reports by CDC.

Joint pain supplements are meant to not only ease aches and pains associated with aging but potentially slow down the progression of joint degeneration.

“Severe joint pain is more common among adults with arthritis who also have other chronic conditions including diabetes (40.9%), heart disease (34.1%), and obesity (31.7%), and among adults with a disability (45.6%)”, studies done by CDC.

Modern joint pain herbal supplements include active ingredients such as glucosamine, chondroitin, or Methylsulfonylmethane (MSM) that are meant to relieve pain and inflammation, enhance joint mobility, and potentially preserve joint cartilage.

Some products will additionally contain ingredients like collagen peptides, hyaluronic acid, or natural extracts to further support joint health and function. Here’s a look at ingredients and what the existing research says about them.

Natural Ingredients, Supplements, Herbs and Medications To Help Joint Pain

There are tons of supplements for inflammation and joint pain that claim to treat joint pain, but which ones actually work? Here’s a look at 8 of the best supplements for joint pain, and what the existing research says about them.

1. Glucosamine

A natural substance found in cartilage and fluid between joints. Glucosamine is necessary for the synthesis of glycosaminoglycan, which contributes to both the constitution and the actual repair of joint cartilage. It is commonly harvested from shellfish, but there are also artificial versions made in the laboratory.

There are a few different forms of glucosamine used in natural joint pain relief supplements and there is conflicting research about the effectiveness of them in treating joint pain.

Is Glucosamine good for joint pain? According to the Mayo Clinic and Medline Plus, Glucosamine sulfate appears to show the most promise in reducing pain for those with osteoarthritis and may slow the deterioration of joints.

On the other hand, the Glucosamine/chondroitin Arthritis Intervention Trial (GAIT)[2] found glucosamine HCl combined with chondroitin sulfate to significantly improve pain in those with moderate to severe joint pain.

2. Chondroitin

A substance naturally found in cartilage and in supplement form is from animal sources like cows, pigs, or sharks. This ingredient has excellent anti-inflammatory properties.

Chondroitin significantly reduced joint pain and the narrowing of joint space, as well as improved overall physical function in those with osteoarthritis, as discussed in this study[3].

Some research shows taking this on a long-term basis (upwards of 2 years) may even be effective in slowing the progression of osteoarthritis.

3. MSM

A natural sulfur-based chemical found in the body and several types of plants necessary for the formation and repair of connective tissue.

This study[4] discusses how MSM can reduce joint pain and inflammation, enhance joint mobility and range of motion, potentially preserve joint cartilage, and even improve post-exercise muscle soreness.

4. S-adenosyl-L-methionine (SAMe)

SAMe is produced by the liver from an amino acid, methionine, and is commonly added to joint pain relief natural supplements to reduce pain, inflammation, and improve overall physical function.

One study[5] found this substance alone to be just as effective in managing osteoarthritis in the knee as Celebrex, a common anti-inflammatory drug.

SAMe may also help treat depression and some liver diseases, but it is not recommended for those who suffer from mental illness, especially bipolar disorder.

5. Turmeric

A popular spice in the Indian cuisine that is believed to have a multitude of beneficial properties. Turmeric has antioxidant and anti-inflammatory properties due to its active compound, curcumin.

This spice has been found to treat symptoms of arthritis just as well as ibuprofen and may be beneficial in the treatment of diabetes, colitis, and various cancers.

Turmeric is also commonly used in both Chinese and Indian medicine to modify the response of the immune system and prevent further joint inflammation caused by arthritis.

RELATEDHealth Benefits of Turmeric

6. Boswellia

Also known as Indian frankincense, Boswellia is appreciated for its ancient anti-inflammatory and analgesic properties commonly used in Ayurveda medicine.

Several studies have found Boswellia to relieve pain in patients who suffer from osteoarthritis or rheumatoid arthritis.

This study also mentions Boswellia’s potential in reducing the degradation of glycosaminoglycan, preventing further loss of cartilage.

7. Devil’s Claw (harpagophytum)

An herb commonly used in South Africa that is well known for its pain-relieving and anti-inflammatory effects mainly due to its active compound, harpagoside. It may be effective in reducing joint pain in those with osteoarthritis, minimally reducing the need for anti-inflammatory drugs.

8. Fish oil

This supplement is rich in omega-3 fatty acids which play a role in the structure of cells, provide useful energy, and is popularly known for its anti-inflammatory properties.

DHA and EPA can treat different types of arthritis, but have been found to significantly reduce joint stiffness and tenderness specifically in those with rheumatoid arthritis, according to the Arthritis Foundation.

There are several omega-3 fatty acids, but the most researched are docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which are highest in salmon.

Tips for Choosing the Joint Pain Supplements For You

Choosing supplements for joint pain and stiffness can be a difficult task, especially since there are several brands with various ingredient combinations and dosages.

The first thing to do before starting any supplement is to discuss it with your healthcare provider to ensure the supplement will not interfere with any pre-existing health conditions or any medications you are taking.

Start by looking into common supplement brands and review the labels. Check to see if the supplement contains important joint-protective active ingredients.

It is also important to look at the additional ingredients – typically, the longer the “additional” ingredient list is, the more additives and fillers there are.

It would be great if arthritis joint pain relief supplements could be approved by the Food and Drug Administration (FDA), but the FDA “does not have the authority to review dietary supplement products for safety and effectiveness before they are marketed.”

Each company is responsible for ensuring their joint pain products are safe before selling them. Several companies will have their supplements tested by a third-party laboratory for purity and accurate dosages for safety and reputability. Companies will mention additional testing on their website and/or on their supplement bottles.

It is also beneficial to look into the company itself, see if they are rated by the Better Business Bureau, and read up on as many consumer reviews as possible. Reviews can offer valuable information such as specific pros/cons of taking the supplement, potential side effects, and various timeframes for noticeable benefits.

Lastly, do not get stuck on price. Strive to purchase a supplement from a reputable company. Higher quality supplements help joint pain will generally be more expensive, but not always. You are usually paying the higher price for the purity of active ingredients and a shortlist of additional filler ingredients.

How We Chose the Following Supplements for Joint Pain?

In deciding on the best joint pain supplements on the market, we analyzed the formula of each supplement, specifically the active ingredients and doses, as well as verifying whether each supplement is supported by clinical studies or not. We want to ensure the ingredients are helpful in promoting joint health and relieving arthritis-related symptoms.

We have eliminated any joint pain supplements that contain potentially harmful ingredients such as preservatives, artificial colors, fillers, binders, or additives. Such ingredients pose questions about safety and purity and can lead to discomforting side effects or adverse reactions.

Our selection of knee joint pain supplements is sound, as we have looked at quality first and foremost and it is essential to us that each supplement below has the potential to truly support joint health.

The Best Joint Pain Supplements of 2022

In this comprehensive review about Glucosamine, Chondroitin, MSM and Boswellia supplements to help joint pain, you’ll learn the pros and cons for supplements mentioned below:

1. VitaBalance ProJoint Plus

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

VitaBalance ProJoint Plus

VitaPost ProJoint Plus supplement that improves the health of joints. It supports the health of the cartilage and promises to increase overall mobility, thanks to a natural blend of herbal extracts.

  • Form:Capsules
  • Type:Supplement
  • Benefit:Supports cartilage health, joint health and healthy joint mobility
  • Phone & Address:1-888-455-9995; Vita Balance Inc, 7400 Beaufont Springs Drive, Suite 300, Richmond, Virginia 23225, United States, support@vitabalance.net
  • Brand:VitaPost
  • Active Ingredients:Glucosamine Sulfate, Quercetin, Methylsulfonylmethane, Boswellia Extract, Turmeric, Bromelain, Methionine, Chondroitin Sulfate
  • Price:$29.95*
 
 

VitaBalance ProJoint Plus Pros & Cons

Pros

  • Science-backed formula – increased mobility and flexibility in major and minor joints
  • Contains key ingredients such as glucosamine and MSM, but also natural herbal extracts: Boswellia, turmeric, bromelain, quercetin
  • All ingredients are supported by clinical studies
  • GMP quality assured

Cons

  • It may take several weeks before results are observed
  • Must be taken on a daily basis for the full effect
  • Only available online & no trial period offered
  • Quantity of each ingredient is unknown

Recommended Dosage: Take 3 capsules per day, the website does not provide further recommendations on when to take them. You can speak with your pharmacist or doctor for when and how to take it.

2. Joint N-11

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Joint N-11

Joint N-11 is a natural supplement which improves joint and bone health and decreases pain and inflammation in the joints. It restores flexibility and mobility in the knees, back, and hips and supports the hands and wrists.

  • Form:Capsules
  • Type:Supplement
  • Benefit:Protects the joint cartilage for easy movement, supports against nagging joint pain, provides maximum flexibility and mobility
  • Phone & Address:+1 (800) 928-1184; 4610 Prime Parkway, McHenry, IL, 60050, USA; support@zenithlabs.com
  • Brand:Zenith Labs
  • Active Ingredients:Ginger Root Powder, Boswellia Serrata, Turmeric
  • Price:$49*
 
 

Joint N-11 Plus Pros & Cons

Pros

  • Joint N-11 reduces joint pain and inflammation.
  • The product improves flexibility and mobility.
  • Joint N-11 supports bone health.
  • It protects the joint cartilage.
  • The product helps to repair damage to the joints and cartilage.

Cons

  • It may interact with some common medications.
  • It includes soy and rice flour, which are common allergens.

Recommended Dosage: 2 capsules a day with breakfast.

3. Turmeric Curcumin Plus

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Turmeric Curcumin Plus

Turmeric Curcumin Plus is a healthy supplement which supports joint and muscle wellness, brain and cardiovascular health, and it can help you lose weight. In addition, it strengthens the immune system.

  • Form:Capsules
  • Type:Supplement
  • Benefit:Helps support a healthy immune system, enhances muscle and joint health, promotes healthy cognitive functioning
  • Phone & Address:1-888-455-9995; Vita Balance Inc, 7400 Beaufont Springs Drive, Suite 300, Richmond, Virginia 23225, United States; support@vitabalance.net
  • Brand:Vita Balance
  • Active Ingredients:Turmeric, Curcumin, BioPerine
  • Price:$23.95*
 
 

Turmeric Curcumin Plus Pros & Cons

Pros

  • Turmeric Curcumin Plus supports joint and muscle health.
  • This supplement strengthens the immune system.
  • The product helps to improve brain health.
  • Turmeric Curcumin Plus is reasonably priced.

Cons

  • High demand leads to low stock at times

Recommended Dosage: Take 2 capsules once daily 20-30 minutes before meals. Alternatively, you can speak to a doctor or pharmacist on dosing.

4. Move MD

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Move MD

Move MD is an organic joint supplement which can ease joint pain, inflammation, and stiffness and make movement easier and less painful. It’s high in antioxidants which repair joint damage and protect them from future harm.

  • Form:Capsules
  • Type:Supplement
  • Benefit:Reduces Joint Discomfort, helps maintain connective tissue, increases the mobility and flexibility of the joints
  • Phone & Address:(888) 393-4030; 1MD, 1453 W 40 S, Lindon UT, 84042
  • Brand:1MD Nutrition
  • Active Ingredients:Boswellia Serrata, Chicken Collagen, Hyaluronic Acid, Astaxanthin, Eggshell Membrane Collagen
  • Price:$40.99*
 
 

Move MD Pros & Cons

Pros

  • Move MD can decrease joint pain and swelling.
  • It can increase lubrication and ease stiffness.
  • This supplement improves flexibility and mobility.
  • It supports a strong immune system.

Cons

  • The product is not suitable for vegetarians.
  • Results vary from individual to individual.

Recommended Dosage: One capsule per day or as recommended by a healthcare practitioner– with a glass of water and with or without a meal.

5. CurcuminMD

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

CurcuminMD

CurcuminMD is a potent formula with anti-inflammatory properties that can reduce swelling and pain in the joints. This is a healthy supplement full of antioxidants which can raise immunity and support heart and brain wellness.

  • Form:Capsules
  • Type:Supplement
  • Benefit:Improves cognitive health, relieves joint stiffness, protects joints and tissues
  • Phone & Address:(888) 393-4030; 1MD, 1453 W 40 S, Lindon UT, 84042
  • Brand:1MD Nutrition
  • Active Ingredients:Curcumin, Boswellia Serrata
  • Price:$36.99*
 
 

CurcuminMD Pros & Cons

Pros

  • It can reduce joint pain and swelling.
  • CurcuminMD improves brain health.
  • It supports a healthy heart.
  • CurcuminMD is suitable for vegans.

Cons

  • You may have mild side effects like headaches or nausea.

Recommended Dosage: Take 1 capsule twice a day with a full glass of water on an empty stomach or as instructed by a physician. If you are concerned about sensitivity, you can take it with a small meal.

6. 1MD D3

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

1MD D3

1 MD D3 is a potent Vitamin D supplement which delivers 5000 IU per serving, helping to support cell functioning, brain, heart, and respiratory health, bones, teeth, and muscles. In addition, it can aid in calcium absorption.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Aids Proper immune, bone, & brain health, helps maintain a healthy mood & proper muscle function
  • Phone & Address:(888) 393-4030; 1MD Nutrition, 675 N 2800 W #101, Lindon, UT 84042
  • Brand:1MD Nutrition
  • Active Ingredients:Vitamin D3, Avocado Oil
  • Price:$19.99*
 

1MD D3 Pros & Cons

Pros

  • It supports healthy bones and teeth.
  • 1 MD D3 can improve brain functioning.
  • The product can enhance muscle function.
  • It can elevate cell functioning in the body.
  • 1 MD D3 helps calcium absorption.

Cons

  • If you take too much you could have side effects like headaches or fatigue.

Recommended Dosage: Take one capsule, two times per day, with a meal and glass of water, or as suggested by your physician.

7. Doctor’s Best Glucosamine Chondroitin MSM

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Doctor’s Best Glucosamine Chondroitin MSM

Doctor’s Best Glucosamine Chondroitin MSM contains three of the most important ingredients for joint health (glucosamine, chondroitin, and MSM). This supplement prevents the breakdown of cartilage, provides relief from pain and joint stiffness, as well as improves joint weakness.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Supports joint health, mobility, and comfort, promotes overall health for vibrant hair, skin, and nails
  • Brand:Doctor’s Best
  • Active Ingredients:Glucosamine, Chondroitin, Hyaluronic Acid, Methylsulfonylmethane
  • Price:$21.99*
 

Doctor’s Best Glucosamine Chondroitin MSM Pros & Cons

Pros

  • Contains 3 active ingredients proven to promote joint health and treat arthritis-related symptoms
  • Improves joint flexibility and mobility
  • Contains only clinically-studied and tested ingredients

Cons

  • Cannot be taken by those who take medication for high blood pressure or chronic kidney disease (potential interaction)
  • Contains shellfish (for those with allergies)

Recommended Dosage: As a dietary supplement, take 2 capsules twice daily, with or without food. Store in a cool dry place.

8. Zenwise Advanced Strength Joint Support

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Zenwise Advanced Strength Joint Support

Zenwise Advanced Strength Joint Support is recommended to those who are interested in strengthening their joints and reducing the manifestations associated with joint disease. It is manufactured by a reputable company in the field of bone and joint pain supplements.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Supports joint health, and flexibility, eases occasional joint stiffness, provides anti-inflammatory support
  • Brand:Zenwise
  • Active Ingredients:Glucosamine Sulfate KCL, Chondroitin Sulfate, MSM (Methylsulfonylmethane), Bosweillia (Serrata), Curcumin , Hyaluronic Acid
  • Price:$18.97*
 

Zenwise Advanced Strength Joint Support Pros & Cons

Pros

  • Proprietary formula with active ingredients such as glucosamine, chondroitin, MSM, hyaluronic acid
  • Contains natural extracts – Boswellia and curcumin – Increases joint mobility, flexibility, and strength
  • Does not contain gluten, wheat, peanuts, dairy or eggs
  • Good manufacturing practices & money back guarantee

Cons

  • Contains shellfish (for those with allergies)
  • Can not be taken by women who are pregnant or nursing

Recommended Dosage: Take 3 tablets daily, or as directed by your healthcare professional.

9. Schiff Move Free Joint Health Advanced

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Schiff Move Free Joint Health Advanced

Schiff Move Free Joint Health Advanced is a highly effective solution for those who are suffering from different forms of arthritis. It has a unique formula supporting not only the health of the joints but also of cartilage and bone.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Supports mobility, flexibility, strength, lubrication, and comfort + extra cartilage and bone support
  • Phone & Address:1 (888) 532-4574; SchiffCustomerCare@reckitt.com
  • Brand:Schiff
  • Active Ingredients:Glucosamine HCl, Chondroitin, Hyaluronic acid (HA), Calcium Fructoborate (CFB)
  • Price:$18.97*
 

Schiff Move Free Joint Health Advanced Pros & Cons

Pros

  • Combination of type II collagen, boron and hyaluronic acid – excellent joint health support
  • Hyaluronic acid – healthy joints and adequate lubrication
  • Beneficial blend of joint pain vitamins supplements and minerals for bone health – Vitamin D, Calcium, Magnesium

Cons

  • Contains shellfish (for those with allergies)
  • Cannot be taken by women who are pregnant or nursing

Recommended Dosage: Take 2 tablets once a day with a meal. You can also take 1 tablet once daily.

10. Omega XL

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Omega XL

Omega XL is another joint pain supplement that contains an extract derived from green-lipped mussel. The mussels are sourced directly from New Zealand, using sustainable practices and are a rich source of omega-3 fatty acids.

  • Form:SoftGel Capsules
  • Type:Supplements
  • Benefit:Supports joint and bone health, improves mobility, and enhances muscle recovery
  • Phone & Address:1-800-488-8082; 4150 SW 28th Way Fort Lauderdale, FL 33312; support@omegaxl.com
  • Brand:Great HealthWorks
  • Active Ingredients:Flaxseed Oil, Omega 3, Vitamin E, Green Lipped Mussel Oil, and Olive Oil
  • Price:$39.95*
 

Omega XL Pros & Cons

Pros

  • Natural relief from joint pain and inflammation
  • Safe and effective
  • Additional beneficial ingredients – olive oil, vitamin E
  • Improves joint mobility, flexibility, and strength
  • Easy to swallow soft gel caps with no fishy aftertaste
  • Money back guarantee.

Cons

  • Contains shellfish (for those with allergies)
  • The exact amount of each ingredient is unknown
  • More expensive than other muscle and joint pain supplements
  • No information on clinical trials

Recommended Dosage: Take 4 gel capsules daily, preferably with a meal, for the first 8 weeks. All 4 may be taken at once, or two in the morning and two at night — whatever works best for you (according to the official website). Also, a third-party source of information says, the daily recommended dosage is at least 3 capsules.

11. Osteo Bi-Flex

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Osteo Bi-Flex

Osteo Bi-Flex is a joint supplement which works to solve some of the most common complaints associated with arthritis. It contains key ingredients such as glucosamine and chondroitin, as well as natural extracts like Boswellia.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Protects joint, support joint mobility, improves joint comfort
  • Phone & Address:1-888-VITAHELP (848-2435)
  • Brand:Osteo Bi-Flex
  • Active Ingredients:Glucosamine, Vitamin C, Manganese, Joint Shield™ 5-Loxin Advanced
  • Price:$13.29*
 

Osteo Bi-Flex Pros & Cons

Pros

  • Reduces joint pain and stiffness and supports long-term joint health
  • Potential to reduce further cartilage breakdown
  • Claims to make a difference in 7 days
  • Reputable company

Cons

  • Hard to swallow, due to the large size of the tablets

Recommended Dosage: Take 2 tablets per day, preferably with food.

12. Aleve

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Aleve

Aleve is an over-the-counter non-steroidal anti-inflammatory drug, recommended for arthritis pain. It is also commonly used for headaches and backaches.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Works on minor aches and pains due to minor arthritis, back and muscle aches, and headache
  • Phone & Address:800-395-0689; Bayer Consumer Health, Attn: Consumer Relations, P.O. Box 811930, Boca Raton, FL 33481-1930
  • Brand:Aleve
  • Active Ingredients:Naproxen Sodium
  • Price:$13.29*
 

Aleve Pros & Cons

Pros

  • Easy to open arthritis cap – beneficial for those who have hand arthritis
  • Active ingredient – naproxen sodium – temporary relief from joint pain
  • Strength lasts up to 12 hours, only two pills per day
  • May also bring down the fever
  • Temporarily blocks the production of prostaglandins, which are responsible for pain sensation

Cons

  • May interact with prescribed medications
  • Cannot be taken by those who suffer from cardiovascular disease (risk of thrombotic events), peptic ulcer or gastrointestinal bleeding, or liver disease

Recommended Dosage: Take one tablet every 8 to 12 hours for as long as your symptoms last and that within the first hour, it is ok to take two.

13. Instaflex Advanced

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Instaflex

Instaflex Advanced promises advanced joint support, containing UC-II collagen as its star ingredient. With carefully-resourced ingredients and clinically proven research, Instaflex Advanced can be used to fight joint disease.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Promotes joint health, provides joint relief, supports joint health, flexibility and mobility
  • Phone & Address:1-800-436-0920; support@instaflex.com
  • Brand:Instaflex Advanced
  • Active Ingredients:Turmeric Extract, Resveratrol, AprèsFlex®-Boswellia serrata Extract, Hyaluronic Acid, Bioperine®-Black Pepper Extract (fruit)
  • Price:$69.99* + Shipping
 

Instaflex Pros & Cons

Pros

  • Improves joint mobility and flexibility; improved joint health for an active lifestyle
  • The formula guarantees relief in less than a week, with only one capsule per day
  • Fast and effective for pain relief
  • Potent ingredient – UC-II collagen – more effective than glucosamine; used in combination with chondroitin, it improves overall joint function
  • Natural extracts – turmeric, resveratrol – anti-inflammatory and antioxidant properties to reduce joint damage

Cons

  • Cannot be taken by pregnant or nursing women
  • Not recommended for those allergic to salicylates
  • May interact with other prescribed medications
  • Not recommended for those with gastric problems

Recommended Dosage: Take 1 capsule daily, with or without food or as directed by your physician.

14. NOW MSM Powder

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

MSM Powder

Now MSM Powder is a powder and contains MSM as its main ingredient.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Supports healthy cartilage
  • Phone & Address:888-669-3663
  • Brand:Now
  • Active Ingredients:MSM (Methylsulphonylmethane)
  • Price:$12.99*
 

Now MSM Powder Pros & Cons

Pros

  • Available in the form of powder so it’s very easy to take
  • Supports joint health with the potential to preserve further breakdown of cartilage
  • Does not contain gluten, dairy, eggs, gluten, nuts; non-GMO;
  • GMP quality assured and clinically tested

Cons

  • Can not be taken by pregnant or nursing women
  • May interact with other prescribed medications, such as those for glaucoma

Recommended Dosage: Take 1/2 teaspoon 1 to 2 times daily in juice or other liquid. If intestinal gas occurs, reduce dosage.

15. Kirkland Signature Extra Strength Glucosamine Chondroitin

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Kirkland Signature Extra Strength Glucosamine Chondroitin

Kirkland Signature Extra Strength Glucosamine Chondroitin offers the perfect blend of glucosamine and chondroitin, being recommended to those who are interested in keeping their joints healthy. It is suitable for those who have already been diagnosed with joint disease.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Promote cartilage health and joint health
  • Brand:Kirkland Signature
  • Active Ingredients:Glucosamine Hydrochloride, Chondroitin Sulfate Sodium (Bovine), Croscarmellose Sodium
  • Price:$29.99*
 

Kirkland Signature Extra Strength Glucosamine Chondroitin Pros & Cons

Pros

  • Supports healthy joints and a better range of motion for an active lifestyle
  • Combination of glucosamine and chondroitin – joint lubrication and cushioning
  • Does not contain gluten, lactose, or sugar

Cons

  • Contains shellfish (for those with allergies)
  • Not recommended for pregnant or nursing women
  • May interact with other prescribed medications

Recommended Dosage: Take two tablets daily with a full glass of water.

16. VeraFlex

 

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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

VeraFlex

VeraFlex is an all-natural supplement that promises optimal support to painful joints. It uses ingredients including Univestin UP446 (250mg) and BiAloe Organic Aloe Vera (Aloe barbadensis) Inner Leaf (160mg). This supplement can works fast to reduce joint pain and inflammation. When taken regularly in the morning it may improve flexibility by reducing joint stiffness.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Helps naturally support joint wellness, maintains natural joint mobility and comfort, promotes healthy immune system
  • Phone & Address:1-(800) 671-4180; 8015 SE 28th St, Suite 217, Mercer Island, WA 98040; customerservice@aloecure.com
  • Brand:AloeCure
  • Active Ingredients:Univestin UP446, BiAloe Organic Aloe Vera
  • Price:$31.96*
 

VeraFlex Pros & Cons

Pros

  • Can work on different types of joint pain issues including arthritis
  • Might help slow degenerative joint diseases
  • It can improve lubrication and mobility

Cons

  • For long-term benefits, you’ll need to keep using the product as recommended
  • May not help for serious cases of joint deterioration
  • Some people experience delayed results

Recommended Dosage: Take 1 capsule per day in the morning when you start your day – the website does not provide further instruction on whether to take it with or without a meal.

CAUTION: “Do not take more than the suggested dosage under any circumstances.”

Best Joint Pain Supplements – Frequently Asked Questions (FAQs)

Q: What are the side effects of joint pain supplements?

A: The potential side effects of supplements for joint pain are determined by the ingredients they contain and dosages used. Many people experience temporary gastric discomfort as they become accustomed to the intake of the new supplement.

Common side effects include nausea, vomiting, and diarrhea. Heartburn and abdominal pain may also occur. It is important to read the label of the joint pain supplement before taking it.

As mentioned before, discuss the supplement with your healthcare provider to ensure it will not interfere with any pre-existing health conditions or any medications you are taking.

Always follow instructions to the letter. If concerning side effects appear, discontinue the supplement and see your doctor.

Q: What is the recommended dosage?

A: These are some of the recommended dosages for ingredients contained in natural supplements for joint pain:

  • Glucosamine sulfate – 1500 mg per day
  • Chondroitin sulfate – between 800 and 1200 mg per day
  • MSM – 1500 mg per day
  • Same – between 600 and 1200 mg per day
  • Boswellia – between 900 and 1200 mg per day
  • Fish oil – 1000 mg per day

Note: your doctor or pharmacist may recommend specific dosages for joint pain. Do not exceed those recommended dosages.

Q: Do joint pain supplements work?

A: The answer is yes, BUT they may not work well for everyone. Although joint pain relief products contain active ingredients that reduce joint pain and support overall joint health, not all joint-related issues or diseases can be managed by supplements alone. Patience and consistency are also key. Most supplements for joint pain relief will take time to work and will only work if taken on a regular basis.

Q: Who should buy the best supplements for joint pain and arthritis?

A: Supplements For Joint Pain are generally recommended for those who have had joint/ligament types of surgeries, those beginning to exhibit the first signs of arthritis, and overall for the older population due to normal wear and tear on joints with age.

Joint supplements may also be taken for preventative measures to support the already healthy functioning of joints and potentially delay the aging process and painful symptoms related to joint degeneration.

Q: Can vitamin supplements cause joint pain?

A: Generally speaking, some vitamins will help ease joint pain and improve general health. There’s no evidence to show that they actually cause joint symptoms. However, there is a possibility that an overdose of multivitamins can lead to bone or muscle pain, or muscle weakness.

Q: What are the best supplements for joint pain that you can be taken?

A: This article has suggested a number of top joint pain supplements you can consider for treating your joint pain. Read the descriptions carefully and make sure you’ve selected the right product for you. Look at the ingredients, side effects, manufacturer, and price, and read the reviews on the products you like best. In addition, consider other products such as EienHealth Triple Power Joint Support, Joint N-11, Arthrozene and do a joint pain relief supplement comparison like Instaflex Joint Support vs. MoveMD and GNC TriFlex vs. Heal-n-Soothe.

Q: Can you buy joint pain supplements at local or online stores?

A: Yes, there are many of these products available at online stores, like joint pain supplements Amazon and joint pain supplements GNC. There are also a number of brands which are sold in offline stores like Walmart joint pain supplements or joint pain supplements Costco.

Q: Should you give glucosamine and chondroitin supplements a try?

A: Glucosamine and chondroitin are substances which exist naturally in the connective tissue, and they are very effective at healing joint tissue and helping to lessen arthritis symptoms. This is especially true if they occur together.

If you are considering taking a supplement, there are some health warnings you have to note. For example, glucosamine comes from seafood, so if you have an allergy you should avoid joint pain supplements. Glucosamine is not suitable for people with diabetes, asthma, glaucoma, high cholesterol, and high blood pressure.

Chondroitin is not suitable for people with asthma, blood clotting disorders, or prostate cancer.

Alternative Therapies – What Other Options Keep the Joints Healthy

Now that you’re aware of some of the best joint pain supplements on the market, here are some alternative therapies for arthritis that you could also consider.

Topical Creams and Gels – These creams are meant to be massaged into your skin. They contain ingredients like capsaicin which stimulate nerve endings, helping to block pain receptors. Australian Dream, Biofreeze, Aspercreme, and Penetrex Cream are the few brands to consider for joint pain relief.

Physical Therapy – A physical therapist can help you with body movement and correct positioning, which can ease your symptoms. They can also provide you with equipment to help you like braces and splints.

Electrical Stimulation – This involves placing electrodes on the part of your body that’s in pain and delivering electrical stimulation.

Acupuncture – These small needles placed in your body at various points can improve your blood flow and stimulate nerves, muscles, and connective tissue. This can stimulate natural pain killers in the body.

Massage – Massage is a good solution, but not when you are actively in terrible pain. Otherwise, the manipulation of your muscles may lessen the pain and swelling associated with arthritis.

When to See a Doctor

The rule of thumb is that if your joint pain and swelling last more than 2 weeks, you should go see a doctor. Of course, if the pain is really bad you may want to make an appointment before that. There’s a good chance that your physician will refer you to a specialist like a rheumatologist. This is a doctor who focuses specifically on arthritis and other joint conditions.

Final Verdict

Natural supplements for joint pain are meant to help improve the health of joints, reduce pain, and enhance mobility to continue living an active lifestyle.

All of the joint pain supplements mentioned above contain active ingredients beneficial for typical aches and pains with the potential to preserve cartilage and slow down the progression of joint degeneration.

Do not hesitate to try a variety of joint pain supplements that work and which is best for you. Everyone’s body is different and has different needs, which is why there are so many joint pain products available.

When trying new knee and joint pain supplements, it may be a good idea to keep a diary of how you feel each day and any differences you notice in order to eliminate supplements that either do not work for you or cause negative side effects.

Unfortunately, arthritis is a progressive condition and drastically affects the overall quality of life. With the help of joint pain supplements online, you may find some relief from your symptoms. Choose the best joint pain supplements Glucosamine, Chondroitin, Boswellia, and MSM for Joint Health.

*The views and opinions expressed on this page are strictly those of the Editor. Results may vary from person to person and cannot be guaranteed.

Sources

Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

1. Senthelal S, Li J, Goyal A, et al. Arthritis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls. Source
2. Guy GP, Zhang K, Bohm MK, et al. Vital signs: changes in opioid prescribing in the United States, 2006-2015. MMWR Morbid Mortal Wkly Rep. 2017;66(26):697–704. Source
3. Glucosamine and chondroitin for osteoarthritis pain. Arthritis Foundation. Source
4. Moon JM, Finnegan P, Stecker RA, et al. Impact of glucosamine supplementation on gut health. Nutrients. 2021;13:2180. Source
5. Daniel Clegg, M.D., University of Utah; Marc Hochberg, M.D., M.P.H., University of Maryland; Julian Leakey, Ph.D., U.S. Food and Drug Administration. Source
6. Rheumatoid arthritis. Source
7. Boswellia Serrata, A Potential Antiinflammatory Agent. Source
8. Supplement and Herb Guide for Arthritis Symptoms . Source
9. Jones PJH, Rideout T. Lipids, sterols, and their metabolites. In: Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR, eds. Modern Nutrition in Health and Disease. 11th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2014. Source
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Author
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Jaime Buffie, MS, RDN, LDN

Jaime began her career as a Dietitian at the St. Cloud, Minnesota V.A. and later transferred to the Orlando V.A. in Florida. Jaime thri...

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