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Most Popular Weight Loss Supplements & Diet Pills [Expert Reviewed]

Most Popular Weight Loss Supplements & Diet Pills [Expert Reviewed]

Here are the most popular diet pills and weight loss supplements, reviewed by science.

best weight loss supplements and diet pills

The most popular weight loss pills and supplements, reviewed by science.

Each product we feature has been independently selected and reviewed by our editorial team. If you make a purchase using the links included, we may earn a commission.

Diet Pills – Overview

Weight-loss pills, be they prescription or over-the-counter, use a variety of mechanisms for burning fat and losing weight. Some use ingredients that speed up metabolism, like caffeine. This initiates the fat-burning process of thermogenesis.

Other diet pills suppress hunger, so you don’t overeat, or so you don’t crave carbohydrates. There are pills specifically geared towards those who are following a keto diet. They include extra ketones, which keep the body in a fat-burning state.

No diet pills work to result in ‘miraculous’ weight loss. A good diet and exercise will always be part of the equation, but there are some diet pills that are known to be better than others, so it’s important to look at all of the factors when choosing the best one for you.

Here are the most popular diet pills of the year-

Best Diet Pills

1. PHENOCAL

a) Ingredients – Hoodia Gordonii, Green Tea Leaf Extract, Chromium, Folic Acid, Biotin, 5HTP, Conjugated Linoleic Acid (CLA), Flucoxanthin, Glucomannan, Cocoa Extract, Vitamin B1, Vitamin B2, Vitamin B2, Vitamin B5, Vitamin B6, and Vitamin B12.

b) Manufacturer Claims

  • You might burn more fats due to increased body temperature
  • Your metabolism can improve
  • Makes you feel full thereby improving your eating habits
  • Can boost your physical activity

c) Advantages

  • May offer long-term weight loss support benefits
  • It uses ingredients that have scientific research backing their potency to maintain healthy body weight
  • Doesn’t contain any stimulants, including caffeine
  • Provides a wide range of vitamins which may support overall health

d) Disadvantages

  • For best results, users need to maintain a regular exercise routine
  • Some people find the ingredients as too many to be in a single supplement
  • Healthy dieting may be necessary when taking this product as it may not work independently

e) Side Effects

  • Some people may experience a feeling of nausea, headaches or dizziness
  • Contains Bioperine which may cause stomach issues and itching on some users

2. LEAN BEAN

a) Ingredients – Chilone, Konjac Fibre, Glucomannan, Chromium Picolinate, Vitamins B6 and B12, Chloride, Zinc, Green Coffee, Turmeric, Garcinia Cambogia, Piperine, Acai Berry

b) Manufacturer Claims

  • You’ll burn fat like a professional fitness model.
  • You’ll achieve your body goals.
  • The product is easy to use.
  • It includes the safest, best ingredients.

c) Advantages

  • Includes some anti-inflammatory ingredients and fiber.
  • The product gives you energy in the form of caffeine.
  • It contains vitamins and minerals.

d) Disadvantages

  • You have to take 4 large capsules a day.
  • It contains a lot of caffeine.
  • This product is very expensive.
  • It doesn’t work for weight loss.

e) Side Effects

  • Caffeine can make you jittery and nervous.
  • Bioperine could lead to itching, stomach complaints, nausea.

3. PHENQ

a) Ingredients – α-Lacys Reset, Nopal, Caffeine, Capsimax Powder, Chromium Picolinate, L-Carnitine Furmarate.

b) Manufacturer Claims

  • It targets 5 different elements of weight loss.
  • PhenQ can burn fat.
  • It blocks fat production.
  • The supplement curbs your appetite.
  • It can increase your energy.
  • It may improve your mood.
  • This is a high-quality product.

c) Advantages

  • Provides energy from caffeine.
  • Chromium Picolinate may help improve insulin sensitivity.

d) Disadvantages

  • The supplement is very pricey.
  • The caffeine may make you jittery.
  • The capsules are big and hard to swallow.
  • None of the weight loss claims are true.

e) Side Effects

  • The caffeine could increase anxiety and also keep you awake.

4. HYDROXYCUT

a) Ingredients – Robusta coffee extract (as C. canephora robusta), Caffeine

b) Manufacturer Claims

  • This product will help you lose weight fast.
  • You will have more energy to get through the day.
  • You’ll achieve your weight-loss goals.

c) Advantages

  • The product will give you energy which helps you be more active.

d) Disadvantages

  • It’s missing any key weight-loss ingredients.
  • It may cause you trouble sleeping if you take it in the evening.
  • Some of their diet products are drink mixes with very sweet flavors. Not everyone will enjoy these.

e) Side Effects

5. LEAN PM

a) Ingredients – Vitamin B6, 5-HTP, L-Theanine, Magnesium, Melatonin, Bioperine, EGCG

b) Manufacturer Claims

  • This product will enhance your mood.
  • It will give you a more restful sleep.
  • It’s a fat-burner.
  • It doesn’t contain stimulants.

c) Advantages

  • It will enhance your positive mood.
  • It helps you get to sleep faster and have a restful sleep.

d) Disadvantages

  • Bioperine can cause mild side effects like nausea and stomach upset.
  • May interact with some common medications.

e) Side Effects

  • Bioperine can lead to mild side effects like nausea and diarrhea.
  • Melatonin can lead to sleepiness during the day.

6. ACTIVE PK

a) Ingredients – Berberine HCI, Quercetin Dihydrate, Gynnostemma pentaphyllum, Rice Flour, Vegetable Stearic Acid

b) Manufacturer Claims

  • It helps reduce abdominal fat.
  • It curbs hunger.
  • The supplement helps you think more clearly.
  • It will raise your energy level.
  • It will speed up weight loss.

c) Advantages

  • This product contains fiber.
  • Has anti-inflammatory ingredients.
  • It can prevent you from giving in to cravings due to high fiber content.

d) Disadvantages

  • There are other weight loss ingredients which could have been included.

e) Side Effects

  • There are no known side effects of this product.

7. PHEN375

a) Ingredients – L-Carnitine Tartrate, Caffeine, Calcium Carbonate, Cayenne Capsicum, Chromium Picolinate, Dendrobium Nobile Extract, Citrus Aurantium Extract (the US only), Coleus Forskohlii Roots (the US only), Potassium Stearate

b) Manufacturer Claims

  • It will help you lose 2-5 pounds a week.
  • The product speeds up your metabolism.
  • It’s prescription strength.

c) Advantages

  • It gives you additional energy with caffeine.
  • May help improve insulin sensitivity.

d) Disadvantages

  • It may contain allergens.
  • The capsules are large and hard to swallow.
  • It may increase your heart rate.

e) Side Effects

  • It may keep you awake if you take it in the evening.
  • Some customers said they had mild side effects like nausea, anxiety, and dizziness.

8. ALLI DIET PILLS

a) Ingredient – Orlistat 60mg

b) Manufacturer Claims

  • Can help you lose weight when combined with a low fat, low calorie diet.

c) Advantages

  • Reduces calorie absorption.

d) Disadvantages

  • You have to follow a diet while you take it.
  • It’s only for adults over the age of 18.
  • You have to take it with fat-soluble vitamins.

e) Side Effects

  • You may possibly have some significant gastrointestinal issues with taking this product. It is highly recommended you take it at home.

9. SLIMVANCE

a) Ingredients Turmeric, Moringa, Curry Leaves

b) Manufacturer Claims

  • It triggers your body’s natural weight-loss abilities.
  • The product focuses on your hips and waist.
  • It only uses natural ingredients.

c) Advantages

  • Has anti-inflammatory ingredients.
  • It doesn’t give you jitters.

d) Disadvantages

  • The product is missing several popular weight-loss ingredients.
  • The expected weight loss for this supplement is slow.

e) Side Effects

  • There are no known side effects of this product.

10. BIO X4

a) Ingredients – Amylase, Bromelain, Lipase, Green Tea Extract, Caralluma Fimbriata , Probiotic Blend,

b) Manufacturer Claims

  • The supplement improves digestion.
  • It helps you lose weight.
  • This product curbs your hunger.

c) Advantages

d) Disadvantages

  • It can keep you up at night if you take it in the evening.
  • For some ingredients, there is insufficient evidence that they lead to weight loss.

e) Side Effects

  • There are few side effects associated with taking this supplement. It is also gluten-free and allergy-free.
  • It may cause temporary bloating when you first start taking it.

11. LIPOZENE

a) Ingredients – Amorphophallus Konjac (from Konjac root)

b) Manufacturer Claims

  • It will help you meet your weight-loss goals.
  • The product will reduce body fat.
  • This supplement is safe and effective.

c) Advantages

  • The supplement could help you lose weight.
  • There are no known allergens included.
  • Customers say it curbed their appetite due to the high fiber content.

d) Disadvantages

  • There are many popular weight-loss ingredients missing.
  • One bottle only contains 15 servings.
  • You have to take up to 6 capsules every day.

e) Side Effects

How Do We Rank the ‘Best Diet Pills’?

In order to rank each diet pill, we use a rigorous process where we research every element of both company and pill. We look at the reputation of the company, and how reliable and effective their products are in general.

We also look at their certifications in the industry, which is another indicator of how reputable the company is.

The ingredients are a key factor in deciding what the best products are. We look at the scientific research behind each substance, and whether data backs up its weight-loss potential. Naturally, we also look carefully at customer reviews.

Benefits

  • Weight-loss ingredients can lead to at least moderate weight loss and fat burning, as reported in some studies.
  • They give you energy which can help you to be more active.
  • The pills speed up the metabolism, which leads to weight loss.
  • According to the scientific research, these weight loss ingredients also have other healthy properties.
  • Many of them are rich in anti-oxidants.

Side Effects

According to the National Institute of Health, prescription weight loss medications can lead to different side effects depending on the specific pill.

These range from mild effects like diarrhea and stomach pain to more severe consequences like liver problems in rare cases.

Research on Conjugated Linoleic Acid has indicated that it does lead to weight loss, but that there are mild to moderate potential side effects associated with its consumption. These include oxidative stress, insulin resistance, gastrointestinal irritation.

Green Coffee and Tea are high in caffeine, which can make you jittery or nervous and give you a lot of extra energy.

Some people are intolerant of ingesting caffeine. Caffeine is also a diuretic which will send you running to the bathroom a few more times than usual. However, this has no negative effects.

One research study reported mild side effects associated with taking Forskolin which included stomach upset and diarrhea.

What are the Ideal Ingredients for Fast Weight Loss?

  • Garcinia Cambogia Extract – It has a lot of hydroxycitric acid, which can speed up the metabolism and also curb hunger. There’s only minimal research showing that this substance helps with weight loss.
  • Caffeine – It speeds up the metabolism and so it leads to a lot of fat burning. It also gives you extra energy, which helps you be more active. The Mayoclinic says that the amount of weight you can lose from caffeine is limited.
  • Green Coffee Bean Extract – This has a substance called chlorogenic acid, which burns fat. It also has other health benefits.
  • Glucomannan – This is a dietary fiber is often used in foods because it’s an emulsifier. It has been sold as a weight-loss substance for 10 years, although there’s very little evidence to prove this.
  • Green Tea Extract – It initiates the process of thermogenesis, which does lead to weight loss. It has quite a bit of caffeine, which quickens the metabolism.
  • Conjugated Linoleic Acid (CLA) – A collection of chemicals that make up the fatty acid linoleic acid. Research indicated that ingesting CLA does lead to a moderate weight and fat loss.
  • Forskolin – It’s a weight-loss substance that many people think can release fatty acids, burning fat and making weight-loss more rapid. It may also prevent new fat from forming quickly on the body. The evidence that Forskolin is an effective weight loss substance is not very strong.

FAQ

Q: Do weight loss pills really work?

A: There are two types of diet pills – prescription, and over-the-counter supplements. There are some in each category that has some degree of effectiveness, depending on the quality and ingredients.

According to the Mayo Clinic, “All prescription weight-loss drugs approved for long-term use produce significant weight loss compared with placebo.” Supplements have anecdotal reports of effectiveness.

However, weight-loss pills are not a magic solution. The focus of weight loss should always be changing your eating habits and exercising. Pills are only a tool to speed up or enhance the effects of regular weight loss.

Q: What should you look for when buying diet pills?

A: It’s really important to do your research when choosing a diet pill. There are a number of factors to consider. You want the best quality ingredients available, so check the back of the bottle against the list we’ve provided you.

In addition, do your own independent research on the ingredients and on the reliability of the manufacturer.

If you’re looking for a non-prescription option, check that the ingredients really are all-natural. Have a look at the inactive ingredients to see that there aren’t any chemicals, dyes, or artificial flavors. The more organic, the better.

Naturally, the price is a concern, but you should also have a good look at the company’s money-back guarantee. Choose a product with at least 60 days. A 30-day guarantee isn’t long enough for you to try out the pills, see if they work, and send the product back before the end of the period to get your refund.

For any diet pill you’re considering, look at the warnings to see if there are any safety concerns. There may be concerns listed for people with specific issues or illnesses or just general safety concerns. Another way to find out about safety issues is to research the product to see what’s been said about it.

Finally, look into the scientific research both about the products that interest you – if there is any – and about the ingredients included. It’s important that you be aware of exactly what you’re putting in your body.

Q: Who should buy weight loss pills?

A: Weight-loss pills are intended specifically for people who have weight-related health issues. It’s also for individuals who are at risk of having health problems due to overweight or obesity.

Someone is defined as overweight if they have a BMI (Body Mass Index) of more than 25. Obese is defined as having a BMI of over 30.

This is a decision that you must discuss with your doctor before beginning a regimen of diet pills. The physician will consider your medical history, the medications you are currently taking, and the benefits of weight loss to your overall health and lifestyle.

Not every person who is overweight or obese should be taking diet pills. Your doctor may decide that a special diet or other lifestyle change is more appropriate for you, or that you may succeed better at.

Q: What is the best over the counter diet pill to get rid of belly fat?

A: There are no over the counter diet pills that will get rid of body fat. Green tea extract contains an anti-oxidant called EGCG which may help increase fat utilization, although you should not expect any miraculous results from this.

Q: Which weight loss pills are safe?

A: There’s no guarantee on the safety of any these diet pills, including those which are prescription. This is because medications behave differently depending on the individual.

Both prescription and over-the-counter supplements have the potential for side effects or allergic reactions. This is yet another reason to consult with your physician before taking weight-loss pills.

Q: Can children or teenagers take weight-loss pills?

A: Weight-loss pills are not intended for children or teenagers. Most prescription diet pills are approved for adult use only, and this is also true of over-the-counter diet supplements.

Conclusion – What Else You Should Know

The bottom line is without proper diet and exercise none of these diet pills work. The bottles make a variety of claims, but they will not result in miraculous weight loss. We reviewed the most popular diet pills out there for the year and some information about each one.

Hopefully, this will help you decide both if a diet pill is right for you, and which one you may choose for your own weight-loss program.

Remember to do your own personal research on the ingredients and on the products. It’s important to learn as much as you can about any product that you’ll be putting in your body.

In addition, it’s essential that you see your doctor before you start taking a diet pill. Not everyone is medically suited to be taking this type of medication.

Feedback:

References

1. The Return of Rainbow Diet Pills | AJPH | Vol. 102 Issue 9 https://ajph.aphapublications.org/doi/abs/10.2105/AJPH.2012.300655
2. Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products - Cannon - 2001 - Medical Journal of Australia - Wiley Online Library https://onlinelibrary.wiley.com/doi/abs/10.5694/j.1326-5377.2001.tb143404.x
3. Prescription Medications to Treat Overweight and Obesity | NIDDK https://www.niddk.nih.gov/health-information/weight-management/prescription-medications-treat-overweight-obesity
4. American Roulette — Contaminated Dietary Supplements | New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/nejmp0904768
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Ana Reisdorf, MS, RD

Ana Reisdorf has 12 years of experience as a Registered Dietitian. She has a passion for creating incredible health and nutrition conte...

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