The Best Anti-Aging Wrinkle Creams of 2021, According to Dermatologists

*Note– Each product we feature has been independently selected and reviewed by our editorial team. If you buy something through a link on this page, we may earn a small commission. How this works.

Wrinkle Creams Introduction

Over the years, the skin starts to lose collagen, moisture, and elasticity. This can lead to wrinkles, fine lines, dry skin, and dark under-eye circles.

In order to keep your skin looking young and radiant, it’s very helpful to use an anti-aging cream on a daily basis.

These products have the potential to provide your skin with the increased collagen and hydration it needs to remain youthful-looking and wrinkle-free.

What Should You Look For While Picking Out An Anti-aging Cream?

Anti-aging creams are not all alike. There are several factors you should look for when choosing the right anti-aging cream.

Price: is not necessarily one of them. The cream isn’t necessarily effective just because it’s expensive.

Look for prime packaging: Begin by looking at the packaging and finding the name of the manufacturer. Look into whether this is a reputable company that produces quality products.

Customer Reviews: go to the company or product website in addition to beauty store sites and read the product reviews. These may give a good indicator of the strengths and weaknesses of the cream.

Know your skin type: Some creams may specify skin type or issue. For example, “some will be geared towards very dry skin or skin that gets oily,” says Joel Schlessinger, MD, Omaha-based board-certified dermatologist, and cosmetic surgeon.

Look for Key Ingredients: The list of ingredients can also be found on the product label. There are certain active ingredients that should ideally be included in a good anti-aging cream.

Certainly look for a cream with antioxidants, which have the potential to reduce free radical damage for the skin.

These include:

• Retinol
• Vitamin C
• Peptides
• Hyaluronic Acid
• Niacinamide
• BHA

The cream should also ideally include sunscreen or sunblock to protect your skin from UV rays.

What Are The Best Anti Aging Creams Of 2021?

1. Glé Skincare for Wrinkles

Ingredients: Carthamus Tinctorius Seed Oil, Algae Extract, Vitamin E, Jojoba Seed Oil

Pros

• With the rich presence of Vitamin E, this cream may have photoaging photo-protective benefits, a claim that some studies uphold. 
• It is a strong moisturizer and said to also have anti-melanogenic benefits. In addition, it also offers antiaging bioactive compounds from the Algae extract. 
• It uses purely natural ingredients
• May work to diminish facial wrinkles that are stubborn to deal with

Cons

• It is an addition to a daily skin routine that would need prioritizing

Price: Gle for Wrinkles is currently priced at 39.99 for a 118 ml tube. However, there are special discounts for orders with more than one product.

2. L’Oreal Revitalift Anti-Wrinkle and Firming Face and Neck Moisturizer

Ingredients: Pro-Retinol, Centella Asiatica

Pros

• This product is suitable for sensitive skin.
• It can make the skin appear firmer.
• It can improve the appearance of wrinkles and fine lines.

Cons

• Perfumed scent which is a recent addition some consider too strong.
• Missing some good anti-aging ingredients.
• This product is only for day use.

Price: $24.96

3. Neutrogena Rapid Wrinkle Repair Night Moisturizer

Ingredients: Dimethicone, Glycerin, BHT, Retinol, Hyaluronic Acid

Pros

• You should start to see results in a week.
• It contains accelerated retinol SA, a combination of retinol and hyaluronic acid.
• This cream makes wrinkles and crow’s feet less apparent.
• It brightens your skin tone.

Cons

• May cause redness or irritation to sensitive skin.
• It smells strongly of perfume, which many people dislike.
• The product may not be suitable for sensitive skin.

Price: $28 on average

4. Roc Retinol Correxion Deep Wrinkle Anti-Aging Retinol Night Cream

Ingredients: Retinol, Citric Acid, Shea Butter, Squalene, Glycolic Acid

Pros

• It can be used at night to improve wrinkles while you’re sleeping.
• The cream can repair and renew the skin.
• It’s rich in essential minerals.

Cons

• It may cause redness or a rash to sensitive skin.
• Some users found it totally ineffective for their skin.
• The product may contain allergens.

Price: $22.99

5. Redermic R Eyes Retinol Eye Cream

Ingredients: Glycerin, Caffeine, Dimethicone, Citric Acid, BHT, Retinol

Pros

• This cream can reduce the look of wrinkles and crow’s feet.
• It can improve the appearance of dark circles under the eyes.
• The product was developed by dermatologists.

Cons

• Some users saw no change in their skin at all.
• May cause a rash in users with sensitive skin.
• Expensive compared to other brands.

Price: $46.95

Results: This is a popular and well-liked anti-aging cream. It did get some excellent reviews from people who were pleased with the improvement in their skin. It did cause a rash for a minority of people and was ineffective for a few users.

6. Resveratrol Lift Night Infusion Cream

Ingredients: Peptides, Hyaluronic Acid, Ceramides, Resveratrol



Pros

• The product is suitable for all skin types.
• It can make the skin appear firmer.
• This cream moisturizes the skin around the eyes.

Cons

• May cause a rash or acne in very sensitive skin.
• It has a strong perfume smell that some people don’t like.
• It’s ineffective for some users.

Price: $99 + free shipping

Results: The vast majority of reviews for this product were positive. People were particularly pleased with this cream as a moisturizer, but also appreciated its anti-aging benefits. It can cause acne breakouts in sensitive skin, or a rash. Apparently, this product does have a strong perfume smell which some people dislike.

7. TruSkin Naturals Vitamin C Serum

Ingredients: Aloe Vera, Vitamin E, Jojoba Oil, Ethyl Hexyl Glycerol, Witch Hazel



Pros

• It’s rich in collagen-producing anti-oxidants.
• The serum can make the pores appear smaller temporarily.
• It could improve the skin tone and clarity of the skin.

Cons

• The serum is only 72% organic.
• May cause an allergic reaction in a minority of users.
• In some users, may dry out the skin.

Price: $19 – 35.99, depending on where you purchase it.

Results: Over 70% of the reviews gave 5 stars. This is a well-loved, trusted product that may do wonders for your skin. In addition, the customer service department is apparently extremely responsive and willing to help make the customer happy.

8. Olay Regenerist Micro-Sculpting Cream

Ingredients: Glycerin, Isohexadecane, Niacinamide, Hyaluronic acid, Citric Acid



Pros

• The cream hydrates the cells in the top layer of your skin.
• It improves the appearance of wrinkles and fine lines.
• It’s an excellent moisturizer.

Cons

• The product doesn’t contain retinol.
• It may cause a reaction to sensitive skin.
• They suggest visible results in a day, which is a very lofty claim.

Price: $27.50

Results: Almost all of the reviews about this product are quite positive. Customers were happy with the results, although they may not often have come on one day. No major complains about this product were noted.

9. Restore & Renew Face & Neck Multi Action Serum

Ingredients: Dimethicone, Glycerin, Butylene glycol, Retinol



Pros

• It can help improve the appearance of fine lines on the face and neck.
• The cream can make your skin appear firmer.
• It’s an advanced anti-wrinkle cream.

Cons

• It had no effect on some users.
• The bottle is quite small.
• It has a strong perfume smell that many people don’t like.
Price: $22.66
Results: This is a well-liked product which got a lot of positive reviews. A small percentage of users got not effect from the cream, but most did find that their wrinkles and fine lines did diminish.

10. Cosmedica Hyaluronic Acid Serum

Ingredients: Hyaluronic acid, Benzyl Alcohol



Pros

• It makes the skin brighter and more radiant.
• The cream reduces the appearance of wrinkles and lines on the skin.
• The product moisturizes the skin.

Cons

• The product only has one ingredient – hyaluronic acid
• Some users found that it dried out their skin.
• Benzyl Alcohol is hard on sensitive skin.

Price: $35.25

Results: This serum got mostly positive reviews. Some users were disappointed that the serum was actually not 100% hyaluronic acid as promised. There was a small minority that got no results at all from the product.

11. Skin Caviar Luxe Cream

Ingredients: Ethylhexyl Palmitate, Glycerin, Cyclomethicone, Cyclopentasiloxane



Pros

• It hydrates the skin.
• The product tones the skin.
• It makes the skin soft and supple.

Cons

• It has a strong fragrance.
• The product is wildly expensive.
• There are some controversial ingredients, including parabens, petroleum, fragrance, dyes and benzyl alcohol.

Price: $505

Results: On the whole, users were very happy with this product. They should be, at this price. There are many good creams that are cheaper, so it’s hard to imagine that this one is that much better. Some users didn’t like the perfume-like smell.

What Are The Benefits Of Using An Anti-aging Cream?

Using an anti-aging cream has many benefits to both your skin and your quality of life on the whole.

Some of these include:

• It can improve the appearance of wrinkles and fine lines on your skin.
• Anti-aging cream can reduce the appearance of dark circles and puffiness under the eyes.
• The cream can moisturize your skin.
• It can really boost your confidence.
• This renewed confidence can enhance your physical and psychological health.

How Can Anti-aging Cream Give You The Best Results?

To get the best results with your anti-aging cream, begin by cleansing your face with your regular cleanser.

• Pat your skin dry with a towel.
• Then take some of the creams onto your fingers and begin rubbing it into your skin in a circular motion for best absorption.
• Cover your entire face and neck with the cream.
Customer Questions and Answers

At what age should you start incorporating an anti-aging cream into your skincare routine?

The ideal time is around the age of 30, but you can actually begin using anti-aging cream as young as 21. If you’re very concerned about getting wrinkled skin, you may want to begin with focusing on sunscreen use.

What are the best ingredients to look for in an anti-aging cream to combat wrinkles?

There are some key ingredients that you should look for when you buy an anti-aging cream.

These include:

Retinol – This is a form of Vitamin A, and it’s known to have amazing anti-aging properties. It can stimulate collagen production in the skin.

Vitamin C – Topically vitamin C can prevent hyperpigmentation and function as an antioxidant. It can be found in foods like fruits and vegetables.

Peptides – These are the building blocks of proteins in our body. Collagen already exists in the body, but it diminishes with age. Topically peptides can diminish the appearance of wrinkles.

Hyaluronic Acid – This natural acid draws hydration, making it a great moisturizing agent that improves the appearance of fine lines and wrinkles. Research in 2018 confirmed that hyaluronic acid can improve the overall appearance of wrinkles.

Niacinamide – This is Vitamin B3, a water-soluble vitamin that can reduce inflammation in the skin. According to studies, Niacinamide can improve the overall redness in the skin.

Is it beneficial to use different formulas for morning and night?

It is only beneficial to use different formulas in the morning and at night if they have different targets. It is important to consult with your Dermatologist to decide on a regimen ideal for your skin needs.

What treatments do you recommend for wrinkles and other signs of aging?

We recommend starting with a hyaluronic acid serum in the morning along with a sunblock. In the evening, a retinol containing product is ideal and can be supplemented with other products depending on the desired outcome.

Do you have any favorite anti-aging creams that you recommend?

For hyaluronic acid containing serums, Excelagene has been a favorite. For wrinkle and fine lines, Stemuderm is an excellent product.

Conclusion

At this point, you should have all of the information that you need to choose the best anti-aging product for your skin.

Remember to look for a cream that matches your skin type, and that deals with the particular issue you want to treat. If you choose a good cream, it should help to reduce the signs of aging on your skin.

You should consult with a dermatologist about your skin issues and show the doctor the product you plan to use to get approval.

Erum Ilyas, M.D., MBE, FAAD

Erum Ilyas, MD is a board-certified dermatologist who performs adult and pediatric medical dermatology, cosmetic dermatology, and skin ... [Read Full Bio]

READ THIS NEXT