Fact Checked
Medically reviewed by 
No matter how old you are, dermatologists agree that taking care of your skin is essential. It’s never too early or too late to start. Whether you’re in your 30s, 40s, 50s, or even older, having a regular skincare routine with a good wrinkle cream can really help your skin.
Too much sun exposure and smoking are the main reasons why your skin might wrinkle prematurely. To avoid wrinkles, it’s important to limit sun exposure and not smoke.
Research from the NCBI explains that as you get older, your skin’s connective tissue isn’t as healthy.[1] This leads to less elastin and collagen, which are important for your skin’s firmness. This is why you might notice fine lines and wrinkles.
Some people choose to use wrinkle creams to reduce the appearance of wrinkles. This article explores some of the best wrinkle creams available online and talks about when it’s a good time to start using them, among other things.
What Causes Aging?
Scientists are studying why we age, with research from the Max Planck Institute Biology for Aging indicating that as we grow older, our genetic material, cells, and tissues accumulate damage that our bodies can’t repair, leading to loss of abilities as we age.
However, the exact causes of this molecular damage and why young organisms can repair it while older ones can’t remain unclear. Researchers agree that various factors contribute to aging, and when crucial processes deteriorate, they can accelerate aging.
Conversely, improving these processes may improve health as we age and extend our lifespan, known as “hallmarks of aging” by scientists.
Our Top Picks of 2025
Best Collagen Cream for Wrinkles: XYZ Smart Collagen
Read The ReviewsBest Wrinkle Filler: Beverly Hills MD Deep Wrinkle Filler
Best Anti-Wrinkle Skin Cream: Skinception Kollagen Intensiv
Best Skin-Smoothing Treatment: InvisiCrepe Body Balm
Best Anti Wrinkle Serum: Instant Wrinkle Reducer
Best Firming Neck & Face Cream:City Beauty Multi Action Sculpting Cream
Best Anti-Aging Eye Cream for Wrinkles: Serious Skincare Insta Tox
Best Face Cream for Wrinkles and Anti-Aging: Tru Alchemy Quench Crème
Best Anti Aging Moisturizer: Olay Regenerist Micro-Sculpting Cream
Best Anti Aging Night Cream: Roc Retinol Correxion Deep Wrinkle Cream
Best Anti Wrinkle Retinol Cream: Neutrogena Rapid Wrinkle Repair
Best Anti Aging Moisturizer With SPF: CeraVe Skin Renewing Day Cream
Best Anti Aging Face Cream: Clinique Wrinkle Correcting Cream
Best for 40s: Drunk Elephant Protini Polypeptide Cream
The Best Anti Aging Creams of 2025
XYZ Smart Collagen – Best Collagen Cream for Wrinkles
Buy on Official Website
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
XYZ Smart Collagen is a potent anti-aging formula clinically proven to visibly lift, tighten, and firm the skin while smoothing out fine lines and wrinkles.
With age, collagen production decreases, causing thin, loose skin. XYZ Smart Collagen restores balance by promoting collagen synthesis, sustaining youthful skin, and enhancing long-term firmness and elasticity.
Key Specs
- Form: Cream
- Type: All Skin Types
- Benefit: Makes skin firmer and more smoother
- Brand: XYZ Smart Collagen
- Active Ingredients: Knipholone, Bulbine Frutescens, Acetylated Polymannose
- Usage: Apply twice a day, morning and night to freshly cleansed skin.
- Price: $49.99*
XYZ Smart Collagen Pros & Cons
Pros
- It claims to eliminate wrinkles and fine lines.
- The product could improve the skin’s texture.
- It may lift and contour your skin
Cons
- Customer results may vary.
- The cream is only available online.
XYZ Smart Collagen Customer Reviews
Fantastic, the best anti-aging cream I have ever had. I have mixed it with my general moisturiser, as I find it a little drying, and its great. I have only been using it for a few weeks, but the skin on my cheeks has been noticeably firmer. Thank you so much. Jayne – Marie Williams
Hi i have Been using xyz for a 3 and half weeks and noticing some differences i am 53 years my skin feels firmer and it looks healthier pores are smaller my small Lines are not reduced yet i am not very wrinkel but hope it Will take the Lines around my mouth and eyei have and reduction of a scar that i have on my left eye quit statisfied at the moment and following your instructions Been using spf 50 last 6 years every Day ? –
Madison Powell
Beverly Hills MD Deep Wrinkle Filler – Best Wrinkle Filler
Buy on Official Website
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
Beverly Hills MD’s Deep Wrinkle Filler is a natural anti-aging solution created by skin experts to smooth away fine lines and wrinkles. This formula works quickly and provides lasting results. It not only enhances skin texture but also lessens redness and swelling, shields against UV rays, and helps repair damage.
Key Specs
- Form: Cream
- Type: All Skin Types
- Benefit: Smooths the skin’s overall appearance, protects from environmental harm
- Brand: Beverly Hills MD
- Active Ingredients: Tightenyl, Diamond Powder, Chondrus Crispus, Camomile Flower Extract
- Usage: Apply a small amount as needed directly to deep wrinkles or fine lines. Pat lightly with fingertip or included applicator until blended.
- Price: $125.00*
Deep Wrinkle Filler Pros & Cons
Pros
- It may enhance the skin texture.
- It nourishes skin for lasting results.
- This formula tightens and lifts the skin appearance
Cons
- Individual results may vary.
- It has a scent that some users may dislike.
Deep Wrinkle Filler Customer Reviews
I’ve only been using the product for about two weeks, and at first I didn’t see much change. At 71, I didn’t really expect to but thought I’d give it a try anyway. As I continue to use the filler, the deep wrinkles around my mouth and on my forehead definitely are softening and looking much better. Each day now, I look forward to seeing additional improvement and I actually DO! – Cynthia Richardson
First saw and i said to myself not another fake add i said what do i haev to loose ill try it so happy i did this product is amazing great results will be ordering more my sisters ordered it as well and nieces once they saw my face i can’t wait to get more i hope i can get a deal on my next order so excited amazing results finally and not a fake add – Nancy
Skinception Kollagen Intensiv – Best Anti-Wrinkle Skin Cream
Buy on Official Website
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
Kollagen Intensiv is an exclusive anti-aging wrinkle cream formulated with powerful peptides that stimulate natural production of collagen, one of its ingredients is clinically shown to reduce the appearance of wrinkles by up to 354%. The manufacturer claims this collagen-boosting formula can replenish collagen levels in the skin that naturally decrease with age.
Key Specs
- Form: Cream
- Skin Type: All Skin Tpyes
- Benefit: Fills in fine lines, diminishes crows feet, minimizes dark circles, evens skin tone
- Brand: Skinception
- Active Ingredients: Retinol, Avena Sativa, Cucumber Fruit Extract, Soybean Oil, Gkycerin, Peptides, Vitamin A, Stabilized Vitamin C, Green Tea, Hydrolyzed Hibiscus Esculentus Extract
- Usage: Apply this cream anywhere on your body that you want to lessen the signs of aging
- Price: $59.95*
Kollagen Intensiv Pros & Cons
Pros
- A renowned cosmetic surgeon developed the formula.
- Kollagen Intensiv can reduce the appearance of wrinkles and lines.
- It firms and tones your skin for a younger look
Cons
- You have to wait 4 weeks for results to start to show.
- It contains soy, which is a common allergen.
Kollagen Intensiv Customer Reviews
Yes, I have been using Kollagen Intensiv® for three months. I have seen an improvement on my crows feet and the sun spots on my face are much lighter. – Cindy M
InvisiCrepe Body Balm – Best Skin-Smoothing Treatment
Buy on Official Website
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
InvisiCrepe Body Balm is a skin-smoothing treatment formulated by the brand City Beauty. This cream helps reduce the appearance of thin, wrinkled, crepey skin by supporting the skin’s barrier function, boosting hydration, and reinforcing the skin’s protein structures for a smoother, firmer, and more supple look.
Key Specs
- Form: Cream
- Skin Type: All Skin Tpyes
- Benefit: Provides long-lasting hydration and healthier, more supple appearance, reduces the appearance of thinning, wrinkled skin for a smoother, younger look and feel
- Brand: City Beauty
- Active Ingredients: Niacinamide, DL Lipids, Ribose
- Usage: Place a quarter-sized amount on the neck, chest, arms, and legs & Massage it until the product is fully absorbed.
- Price: $59.95*
InvisiCrepe Body Balm Pros & Cons
Pros
- It is paraben-free
- It is devoid of phthalates and sulfates
- May help prevent the appearance of dry, thin skin
- Provides 60 Day Money-Back Guarantee
Cons
- The product contains soy, which is an extremely common allergen.
- Cost may be a limitation
- Limited evidence of skin firming and improvement of fine lines, wrinkles.
InvisiCrepe Body Balm Customer Reviews
I use this product daily. I have been using it for a year now and would not go a day without it. My arms and upper legs look great. I have used. I have used it on my chest and neck as well. Love this product. I am 74 years old do if I find something that works I stick with it. – Sharon Jacob
I’m 81 years old and have nice smooth skin with no blemishes. A few years ago I purchased this product and for some reason stopped using it. I found the nearly empty jar in my linen cabinet and started using it. I do have the usual brown spots on my arms, but you get those with age. But, let me tell you, after using what was left in the jar, I ordered another jar and use it after each shower. My skin never felt so soft, moisturized and it smells so good also. Citybeauty has me hooked on this and also they have a new customer. Probably the oldest customer they have ever had! – Donna Schiavoni
Instant Wrinkle Reducer – Best Anti Wrinkle Serum
Buy on Official Website
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
Skinception Instant Wrinkle Reducer is an natural anti-aging serum that claims to firm the skin and get rid of the appearance of fine lines and wrinkles. It also claims to eliminate scars and stretch marks and lighten the skin. This serum also hydrates the skin deeply, moisturizing, and plumping it.
Key Specs
- Form: Serum
- Skin Type: All Skin Tpyes
- Benefit: Diminishes the appearance of wrinkles & fine lines, skin lightening effects, gives instant younger look
- Brand: Skinception
- Active Ingredients: Argireline, Hyaluronic Acid
- Usage: Dab the serum all over your face and neck in generous amounts and rub it in until it’s absorbed
- Price: $59.95*
Instant Wrinkle Reducer Pros & Cons
Pros
- It can relax the facial muscles and smooth lines and wrinkles on face.
- This formula is a rich moisturizer which eliminates dry skin.
- Instant Wrinkle Reducer provides immediate results.
Cons
- There are only 2 primary active ingredients.
- It’s expensive for the small size of the bottle.
City Beauty Multi Action Sculpting Cream – Best Firming Neck & Face Cream
Buy on Official Website
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
City Beauty Multi-Action Sculpting Cream is a powerful blend of 100% organic ingredients that improves the synthesis of collagen and other proteins, firming the skin, improving elasticity, lifting sagging areas, and smoothing wrinkles and fine lines on the face, neck, and chest.
The Multi-Action Sculpting Cream also provides deep hydration benefits, reduces inflammation, repairs and protects the skin barrier, and enhances radiance and glow.
Key Specs
- Form: Cream
- Skin Type: All Skin Tpyes
- Benefit: Boosts hydration, decreases dryness, tightens and lifts sagging skin, smooths wrinkles and fine lines, improves elasticity, decreases inflammation, repairs and protects the skin barrier, boosts radiance
- Brand: City Beauty
- Active Ingredients: Firming Peptide Blend, Acacia Biopolymer, Biomimetic Tripeptide, Caviar Extract, Hydrolyzed Silk, Aloe Vera, Avena Sativa, Green Tea Extract, Comfrey Leaves Extract, Soy Isoflavones, Zinc Gluconate, Copper Gluconate, Allantoin
- Usage: Apply a quarter-sized amount in the morning and at nigh
- Price: $67.00*
City Beauty Multi Action Sculpting Cream Pros & Cons
Pros
- The formula can smooth wrinkles and fine lines
- Multi Action Sculpting Cream can firm and tighten sagging skin
- It’s a parabens, mineral oil, phthalates, and sulfates-free formula
- Provides 60 Day Money-Back Guarantee
Cons
- The free shipping over $50 deal is only for American users.
- This cream is popular and may run low in stock occasionally.
City Beauty Multi Action Sculpting Cream Customer Reviews
Hello there! I am a 79-year-old woman who has been using the Multi-Action Sculpting Cream for quite some time. I have always had fairly good skin, at least as a much younger person! Funny thing happened on my way to becoming 79, I went through so many ‘stages’ that I almost gave up. Then I got some C to my skinity Beauty Multi-Action Sculpting Cream. It has done wonders for my skin. You may call me a “lifer” where this product is concerned. – Geri Bishop
I am 74 years old and have started to have a slight jowl. The Multi-Action Sculpting Cream has been amazing at firming those and improving my jaw line. What surprised me is that the lines on my upper lip (ex-smoker and sax player) seems to have almost disappeared. Can’t recommend it enough to women my age. – Kitty Paino
Serious Skincare Insta Tox – Best Anti-Aging Eye Cream for Wrinkles
Our Rating
Serious Skincare InstaTox is a revolutionary age-slowing serum, meticulously crafted with high-quality, science-backed ingredients. This unique formula targets early signs of aging, combating wrinkles, fine lines, acne, enlarged pores, puffiness, dryness, and crows-feet.
An instant wrinkle-reducer, it tightens skin, delivering a smoother, plumper, and more youthful appearance. Specifically designed to address collagen loss, InstaTox rejuvenates delicate areas like the eyes, diminishing puffiness and dark circles for a refreshed look.
Key Specs
- Form: Cream
- Type: All Skin Types, Dry Skin Type
- Benefit: Promotes collagen levels of the skin
- Brand: Serious Skincare
- Active Ingredients: Hyaluronic, Bakuchiol, Squalene, Butterfly pea flower, Polyglutamic acid
- Usage: Apply a thin layer of the serum on areas affected by wrinkles and fine lines.
- Price: $39.00*
- Where to Buy: Amazon
Serious Skincare Insta Tox Pros & Cons
Pros
- The cream smooths over and blurs enlarged pores.
- It eradicates deep wrinkles and fine lines.
- It is dermatology-tested and skin sensitive approved
Cons
- Results likely to vary a bit across users.
- The ingredients may be limited.
Serious Skincare InstaTox Customer Reviews
Before and after one minute. Yes it works. If you try something else you’ll always come back to this hands down. Lasts the day. The only bothersome thing is you cannot put any eye cream on before hand. It won’t work then … but for a fresh look for the day or eve dinner or special occasion it’s worth it. – Linda m.
Recommended by my sister in law. I have been tight on funds since I am currently in school and not to mentioned stressed. My worry lines were becoming unbearable. I purchased the cream and applied to my troubled forehead(see first pic as I applied) second pic took 10 minutes later. Im obsessed! – Sarah H.
Tru Alchemy Quench Crème – Best Face Cream for Wrinkles and Anti-Aging
Our Rating
Quench Crème is a daily moisturizer containing anti-aging ingredients, including Hyaluronix® to replenish moisture and Bakuchiol to help support firmness and refine texture. It targets skin dryness, roughness, elasticity, and aging. It also focuses on the repair of the skin barrier to improve skin youthfulness.
Key Specs
- Form: Cream
- Type: All Skin Types, Dry Skin Type
- Benefit: Promotes collagen levels of the skin
- Brand: Tru Alchemy
- Active Ingredients: Hyaluronic, Bakuchiol, Squalene, Butterfly pea flower, Polyglutamic acid
- Usage: Dot a pea size of the cream onto your entire face and gently massage it
- Price: $29.25*
- Where to Buy: Amazon
Quench Crème Pros & Cons
Pros
- It is free from irritations as it is a clean formula.
- It helps to boost hydration in the skin’s deeper layers.
- The product is fragrance-free, paraben-free, and sulfate-free.
Cons
- It is only available from the company’s website.
- Results may vary from one user to the other.
Quench Crème Customer Reviews
I love this cream! It’s the best on the market! I’ve been using it a little over 2 mos and can tell a huge difference! I’m 53 years old and it’s helped so much with wrinkles, I’ve noticed my skin is brighter and feels amazing! So worth it! And I’m so glad I found it! – Dawn
This crème has changed my skin in the very best way! I am 62 years young and my skin is so soft and bright. I have people say to me all the time what beautiful skin I have, I truly owe it to this product!read more about review content This crème has changed my skin – Mary
Olay Regenerist Micro-Sculpting Cream – Best Anti Aging Cream for 40s
Our Rating
Olay Regenerist Micro-Sculpting Cream is an anti-aging moisturizer that claims to diminish wrinkles and fine lines. Using its water-binding formula, this product promises to keep your skin hydrated and nourished all day long.
This micro-sculpting formula claims to deliver moisture into the deep layers of the skin surface, which is an important aspect of any hydrating product.If used daily as suggested by the manufacturer, users may begin to observe noticeable results as early as day one.
Key Specs
- Form: Cream
- Skin Type: Normal, Oily, Dry, Combination,
- Benefit: Reduce lines & wrinkles, smoothens skin’s surface, lifts, and micro-sculpt skin’s appearance
- Brand: Olay
- Active Ingredients: Glycerin, Isohexadecane, Niacinamide, Hyaluronic acid, Citric Acid
- Usage: Apply the desired amount and gently massage into the skin until fully absorbed.
- Price: $27.50*
- Where to Buy: Amazon
Olay Regenerist Micro-Sculpting Cream Pros & Cons
Pros
- The cream hydrates the cells in the top layer of your skin.
- It improves the appearance of wrinkles and fine lines.
Cons
- The product doesn’t contain retinol.
- It may cause a reaction to sensitive skin.
- They suggest visible results in a day, which is a very lofty claim.
Olay Regenerist Micro-Sculpting Cream Customer Reviews
I’ve used other Olay face products with no reactions. Bought this due to good reviews, last night was first use on clean face. Work up so red/burnt, puffy face and neck. Feels like sunburn. I do not have sensitive skin and can usually try any product. I’m a little nervous at what is is this product that caused this kind of reaction. Waste of $27.00 – Kelley1
I give up on this product. I followed the regimen of using the daily facials and I use the moisturizer. It felt smooth going on then about an hour later a heavy sticky feeling occurred. Later in the day my face is red and looks like I rubbed crisco all iver my face. I also used it at night and in the morning my face was covered in pimples like I was a teenager again. I stopped using the moisturizer for awhile and skin was fine, went back to it and the same thing occurred. Maybe this is an old jar I bought? Or maybe the skin adviser advised me incorrectly – NitaT
Roc Retinol Correxion – Best Anti Aging Night Cream
Our Rating
RoC Retinol Correxion is an advanced anti-aging night cream that targets even deep-set wrinkles while you sleep. Powered by pure RoC Retinol and an exclusive mineral complex, it hydrates and enhances Retinol efficacy. Clinically proven to reduce wrinkles by up to 50%, it delivers smoother, firmer, and radiant skin by morning.
Key Specs
- Form: Cream
- Skin Type: Sensitive
- Benefit: Anti-ageing, Collagen Boosting
- Brand: RoC
- Active Ingredients: Retinol, Citric Acid, Shea Butter, Squalene, Glycolic Acid
- Usage: Apply to face and neck at night when skin is most receptive for repair and renewal.
- Price: $29.99*
- Where to Buy: Amazon
Roc Retinol Correxion Deep Wrinkle Night Cream Pros & Cons
Pros
- It can be used at night to improve wrinkles while you’re sleeping.
- This anti aging cream can repair and renew the skin.
- It’s rich in essential minerals.
Cons
- It may cause redness or a rash on sensitive skin.
- Some users found it totally ineffective for their skin.
- The product may contain allergens.
Roc Retinol Correxion Deep Wrinkle Night Cream Customer Reviews
I have tried using this product multiple times now I’m hopes that I will have a different reaction. Sadly it’s been the same every time. My under eyes swell and get red and get very dry. Everywhere that I applied it or even near it is itchy as can be. I would not recommend. – Qmik
I don’t know if the product would work as the perfume is so strong I had to wash it off my face and won’t be applying it again. – CINDYM1978
Neutrogena Rapid Wrinkle Repair – Best Anti Wrinkle Retinol Cream
Our Rating
Neutrogena Rapid Wrinkle Repair is an anti-aging cream formulated with dermatologist-proven retinol. It effectively fights fine lines, dullness, wrinkles, and dark spots. Additionally, hyaluronic acid adds plumping moisture to help hydrate and rejuvenate the skin’s appearance.
Key Specs
- Form: Cream
- Type: All skin types
- Benefit: Smoother looking skin, reduces the appearance of fine lines and deep wrinkles
- Brand: Neutrogena
- Active Ingredients: Retinol, Hyaluronic Acid , Glucose Complex
- Usage: Apply twice daily to cleansed face and neck
- Price: $27.99*
- Where to Buy: Amazon
Neutrogena Rapid Wrinkle Repair Pros & Cons
Pros
- It increases the amount of collagen and moisturizes the skin.
- It can eliminate wrinkles.
- It is known to deeply hydrate the skin.
Cons
- It may not work for everyone.
- The cream may give you a rash or allergic reaction.
Neutrogena Rapid Wrinkle Repair Customer Reviews
I bought this crème in 2021 used it for a week and stopped using, l guess I was looking for a overnight miracle….fast forward to 2023 I ran out of my moisturizer. Was looking in my cabinet for something to put on my face, all I had was the Neutrogena rapid wrinkle repair decided to give it another shot and low and behold after using it for a couple weeks my fine lines are disappearing!!! – Georgia
I use this product as a moisturizer over Neutrogena Retinol Pro + at night and as a light moisturizer in the daytime. It makes my skin feel smooth and has not caused any breakouts or other issues. My skin is clear and I find myself going without makeup a lot. I’m not very product-loyal so I’m sure I’ll skip around to try other moisturizers in the Neutrogena line because the brand quality is high while the products are affordable. – Sandr
CeraVe Skin Renewing Day Cream – Best Anti Aging Moisturizer With SPF
Our Rating
CeraVe Skin Renewing Day Cream is an anti-aging moisturizer with SPF and encapsulated retinol that is gradually released into your skin, reducing the appearance of fine lines and wrinkles without irritation.
Formulated with MVE technology, it ensures efficient delivery of ceramides, supporting long-lasting restoration of the skin’s protective barrier. This day cream not only defends against sun-induced aging but also replenishes moisture, promoting radiant and resilient skin without irritation.
Key Specs
- Form: Cream
- Type: All Skin Types
- Benefit: Provides skin hydration, targets hyperpigmentation and brightens the skin
- Brand: CeraVe
- Active Ingredients: Niacinamide, peptide complex, hyaluronic acid, retinol, ceramides
- Usage: Apply liberally 15 minutes before sun exposure
- Price: $27.99*
- Where to Buy: Amazon
CeraVe Pros & Cons
Pros
- The cream contains sunscreen.
- It is known to reduce the appearance of fine lines and wrinkles.
Cons
- Users complained that it is hard to blend.
- The ingredients may cause allergic reactions.
- Some customers noticed it leaves a white cast on the skin.
CeraVe Skin Renewing Day Cream Customer Reviews
Absolutely awful. Leaves my skin feeling even dryer than before I washed it. The cream leaves a film on my face, it causes pilling and looks like dried milk is all over my face. I really wanted to like it considering the high price and suggestions from the skin quiz on the website but I’m returning it to get my money back. – Mandy
This cream feels good while applying but my biggest complaint is that it stays on my skin surface and does not absorb into it. After application it forms a dry, flaky appearance which I find unappealing. My face takes on a dull, matte-like look shortly after use. Have been using it for about 2 weeks and do not detect any skin improvement. Certainly not worth the cost.- Benrica
Clinique Smart Clinical Repair Wrinkle Correcting Cream – Best Anti Aging Face Cream
Our Rating
Clinique Smart Clinical Repair Wrinkle Correcting Cream is wrinkle-fighting cream formulated with natural ingredients that help strengthen and nourish for smoother, younger-looking skin. It is a cutting-edge formula with Peptide Complex™ that helps boost the skin’s natural collagen, fortifying the dermal structure and leaving the skin feeling stronger and looking smoother.
Key Specs
- Form: Cream
- Type: Dry Combination, Combination Oily, Oily , Very Dry to Dry
- Benefit: Visibly reduce the appearance of fine lines and wrinkles, nourishes to help fortify skin
- Brand: Clinique
- Active Ingredients: Peptide complex, hyaluronic acid, soybean seed extract, shea butter
- Usage: Use twice a day, morning, and night
- Price: $77.00*
- Where to Buy: Amazon
Clinique Wrinkle Correcting Cream Pros & Cons
Pros
- It provides intense moisture, especially to dry skin.
- It might be best for younger skin.
Cons
- It may not be effective for all skin textures.
- Reviews say that the cream isn’t worth the price.
- It may not work for everyone.
Clinique Wrinkle Correcting Cream Customer Reviews
I am so glad I read these reviews because after changing to this product from Repairwear, I too have noticed the white bumps. It is only now that I can relate them to this product. I will no longer be using it. I may have to go to any company for my skin care which is very, very disappointing to me. – Sandy
Have been using Clinique since my 20s – now in my 50s – sensitive skin with no issues. Used the Smart Night and Smart Day for years and loved them. For some reason they are discontinued and consultant recommended this – horrible experience with red bumps and white pimples all over my face. Bring back the old Smart Day with sunscreen and Smart Night. Now I need to find another brand for my sensitive skin.- Kim
Drunk Elephant Protini Polypeptide Cream – Best Anti Aging Cream for 40s
Our Rating
Drunk Elephant Protini Polypeptide Cream is a peptide-packed moisturizer infused with growth factors, supportive amino acids, and pygmy waterlily for an immediate enhancement in the skin’s tone, texture, and firmness.
Key Specs
- Form: Cream
- Type: All skin types
- Benefit: Provides moisture to the skin, plumps and firms the skin, soothes and strengthens skin
- Brand: Drunk Elephant
- Active Ingredients: Signal peptide complex, acetyl glutamine, pygmy waterlily stem cell extract, soybean folic acid ferment extract
- Usage: Apply morning and night
- Price: $68.00*
- Where to Buy: Amazon
Drunk Elephant Protini Polypeptide Cream Pros & Cons
Pros
- It helps maintain skin elasticity and strengthens & moisturizes the skin.
- The cream restores younger, revived-looking skin.
Cons
- The product may not be suitable for sensitive skin.
- Some users did not like the packaging and container.
- The product is overpriced compared to its competitors, according to the customers.
Drunk Elephant Protini Polypeptide Cream Customer Reviews
This product left my skin feeling extremely dry. Iv used a lot of moisturizers in the past and this product has to be the worst for MY skin. For someone else this product could be amazing. – chels
The Mini Protini Peptide Cream by Drunk Elephant has a lightweight texture and absorbs quickly. While it provides decent hydration, I didn’t notice a significant improvement in fine lines or texture. The packaging is cute, but the size is quite small for the price. Overall, it’s an okay product, but I expected more noticeable results for the cost.- selfcaregracie
What are the Best Ingredients to Look for in an Anti-Aging Cream to Combat Wrinkles?
There are some key ingredients that you should look for when you buy an anti-aging cream. These include:
Retinol
This is a form of Vitamin A, and it’s known to have amazing anti-aging properties. It can stimulate collagen production in the skin.
Vitamin C
Topically vitamin C can prevent hyperpigmentation and function as an antioxidant. It can be found in foods like fruits and vegetables.
Peptides
These are the building blocks of proteins in our body. Collagen already exists in the body, but it diminishes with age. Topically peptides can diminish the appearance of wrinkles.
What Are The Benefits Of Using An Anti-aging Cream?
Using an anti-aging cream has many benefits to both your skin and your quality of life on the whole. Some of these include:
- It can improve the appearance of wrinkles and fine lines on your skin.
- Anti-aging cream can reduce the appearance of dark circles and puffiness under the eyes.
- The cream can moisturize your skin.
- It can really boost your confidence.
- This renewed confidence can enhance your physical and psychological health.
How We Researched & Picked?
Anti aging wrinkle creams work when they have the right ingredients that work for all skin types. Ingredients that give the skin proper texture, improve skin tone, keep the skin hydrated and boost collagen should be chosen. With the ingredients, your anti aging wrinkle cream should suit your skin type, then only it will be effective.
Well, to help you choose from the best products, we have scaled done the list of the top-rated anti-aging products with the required ingredients in them. We picked products based on the reputed brand, different skin concerns, product and ingredients’ safety, and price.
Furthermore, we had a word with some of the dermatologists to know their opinion about the anti aging creams, analyzed customer reviews, and accumulated all the data to get the best anti aging product picks on the market. Here is the list of the best anti-aging wrinkle creams on the market.
What Should You Look For While Picking Out An Anti-aging Cream?
Anti-aging creams are not all alike. There are several factors you should look for when choosing the right anti-aging cream.
Price: is not necessarily one of them. The cream isn’t necessarily effective just because it’s expensive.
Look for prime packaging: Begin by looking at the packaging and finding the name of the manufacturer. Look into whether this is a reputable company that produces quality products.
Customer Reviews: go to the company or product website in addition to beauty store sites and read the product reviews. These may give a good indicator of the strengths and weaknesses of the cream.
Know your skin type: Some creams may specify skin type or issue. For example, “some will be geared towards very dry skin or skin that gets oily,” says Joel Schlessinger, MD, Omaha-based board-certified dermatologist, and cosmetic surgeon.
Look for Key Ingredients: The list of ingredients can also be found on the product label. There are certain active ingredients that should ideally be included in a good anti-aging cream such as retinol, peptides, and antioxidants.
In addition to this, “Retinoids or retinol has been studied for anti-aging and has been shown to help promote skin turnover, which brings new skin cells to the surface and promotes collagen production, preventing the formation of fine lines and wrinkles,” says Marisa Garshick, MD, a dermatologist at MDCS: Medical Dermatology & Cosmetic Surgery in New York City.
Moisturization and Sun-Protection: Look out for ingredients that moisturize your skin. In an article published by Harvard Health, it was suggested that moisturizing can help with dry skin by giving your skin some water and using a greasy substance to lock it in.[4]
A study in the Annals of Internal Medicine showed that people who use broad-spectrum sunscreen every day have 24% less skin aging compared to those who use it now and then. The study looked at over 900 people for four years and found that even those who started using sunscreen daily in their 40s and 50s had fewer signs of aging on their skin.[5]
How Do Anti-Aging Creams Work?
Anti-aging creams work scientifically, not magically. They mainly do three things: remove dead skin cells for a brighter look, keep your skin moist, and make it more elastic.
A study in Dermato Endocrinology by Ruta Ganceviciene found that retinoids are the most popular and researched anti-aging ingredients.[6] They reduce fine lines and wrinkles by making more collagen and boosting the creation of new blood vessels in the skin, which improves skin color.
Some anti-aging creams also make your skin tone even. This matters because when your skin tone is smooth and consistent, you look younger and have a healthy glow.
How Can Anti-aging Cream Give You The Best Results?
To get the best results with your anti-aging cream, begin by cleansing your face with your regular cleanser.
- Start with a clean, dry face before applying any anti-aging products. This helps the ingredients penetrate your skin properly.
- Read the product instructions carefully. Some creams work best in the morning, while others are designed for nighttime use. Follow the recommended frequency to avoid overwhelming your skin.
- Begin slowly to let your skin adjust. Apply a small amount once a week at first. Watch how your skin responds. If you don’t notice any irritation, gradually increase to 2-3 times per week.
- Use gentle, upward motions when applying the cream. Take special care around the delicate eye area. Don’t pull or tug at your skin.
Be patient and consistent with your routine. Your skin needs time to respond to the ingredients. Most people see results after 3-4 weeks of regular use.
Remember to apply sunscreen during the day, even if your wrinkle cream includes SPF. This extra protection helps maintain the benefits of your anti-aging routine.
When Should You Start Using Anti-Aging Cream?
Dermatologists recommend starting anti-aging skincare in your mid-20s to early 30s, though there’s no strict age requirement.[7] Proactive skincare in your 20s helps train your skin to maintain its health and appearance over time.
Prevention plays a key role in maintaining youthful skin. Start with basic protective measures like applying a broad-spectrum SPF 30 sunscreen daily. Studies show that consistent sunscreen use can reduce skin aging by 24% compared to occasional application.[8]
Remember, your skin’s needs change over time. Start with simple, protective products and adjust your routine as needed. The goal is to support your skin’s health rather than fighting against natural aging processes.
Natural Ways to Prevent Signs of Aging
Effective natural approaches maintain youthful, healthy skin and overall wellness.
Skincare and Nutrition: Apply virgin coconut oil to nourish your skin. Its natural fatty acids boost collagen production and improve skin elasticity. Include essential vitamins and minerals in your diet through whole foods or supplements to support skin health from within.
Sleep and Rest: Prioritize quality sleep each night. Your body repairs and regenerates during sleep, strengthening your immune system and supporting muscle recovery. Good sleep helps your brain function better and keeps your skin looking fresh.
Physical Activity: Move your body regularly through activities you enjoy. Try walking, swimming, yoga, or dancing. Exercise releases mood-boosting endorphins and improves blood circulation, giving your skin a natural, healthy glow.
Mental Wellness: Practice meditation to connect your mind and body. Even five minutes of quiet breathing can reduce stress and promote inner calm. Take regular breaks outdoors to breathe fresh air, which energizes your body and clears your mind.
Lifestyle Habits: Maintain a balanced diet rich in whole foods. Focus on nutrient-dense options that provide energy and support skin health. Make time for activities that bring you joy and laughter – both act as natural stress relievers and contribute to a youthful spirit.
Remember to stay hydrated and protect your skin from sun exposure. These simple daily habits create a strong foundation for natural aging prevention.
Why Trust Us?
We stand as your reliable partner in health and wellness information. Healthcare professionals and industry experts create all our content, bringing years of experience and deep knowledge to every article.
We follow strict guidelines to ensure accuracy and regularly update our information based on current scientific research. From skincare advice to nutrition guidance, we break down complicated topics into clear, actionable steps.
Trust starts with transparency. We maintain high editorial standards and aim to empower you with knowledge to make informed health decisions. Our goal is to be your most trusted source for health and wellness information.
The Final Verdict
When it comes to choosing the best anti-aging creams and wrinkle creams, it’s essential to consider your skin’s specific needs and ingredients that can address those concerns effectively.
Dermatologists recommend looking for products with ingredients like retinol, vitamin C, peptides, hyaluronic acid, niacinamide, and sunscreen for comprehensive anti-aging benefits. Keep in mind that individual results may vary, so it’s important to be patient and consistent with your skincare routine.
Ultimately, the best anti-aging cream for you is the one that suits your skin type and addresses your unique aging concerns.
SIMILAR: Best Skin Tag Removers 2025
Frequently Asked Questions
Q: At what age should you start incorporating an anti-aging cream into your skincare routine?
A: Generally, it is thought that anti aging products should be started around the 50s, right around the time when the wrinkles & drooping skin start to appear more and more permanent.
But in reality, you should start using anti aging products as early as your 20s because this is the age when these products will be the most productive. It is said that, if you begin using anti-aging products in your 20s, you are effectively training your skin how to behave.
Pro Tip: Hydrating your skin regularly with hyaluronic acid creams will train it to remain hydrated, and boosting your skin with retinol creams will provide it with vitamins daily.
“I recommend my patients to start incorporating anti-aging skin care products in their 20s and 30s when our skin slowly starts to lose collagen,” says Y. Claire Chang, a board-certified cosmetic dermatologist at Union Square Laser Dermatology in New York City.
Q: Is it beneficial to use different formulas for morning and night?
A: It is only beneficial to use different formulas in the morning and at night if they have different targets. It is important to consult with your Dermatologist to decide on a regimen ideal for your skin needs.
Q: What treatments do you recommend for wrinkles and other signs of aging?
A: We recommend starting with a hyaluronic acid serum in the morning along with sunblock. In the evening, a retinol-containing product is ideal and can be supplemented with other products depending on the desired outcome.
Q: Do you have any favorite anti-aging creams that you recommend?
A: For hyaluronic acid-containing serums, Excelagene has been a favorite. For wrinkles and fine lines, Stemuderm is an excellent product.
Q: Do anti-aging creams actually work?
A: To gain a better understanding of this question, we consulted plastic surgeon Dr. Sam Fuller, Founder of Sam Fuller Plastic Surgery. He pointed out, “I often encounter patients curious about the effectiveness of anti-aging creams. While these creams can provide some benefits, it’s important to approach them with realistic expectations. Anti-aging creams typically contain ingredients such as retinoids, antioxidants, peptides, and hyaluronic acid, which may help improve skin texture, reduce the appearance of fine lines and wrinkles, and increase hydration.
However, their efficacy varies greatly depending on the specific formulation and concentration of active ingredients. While some individuals may notice visible improvements in their skin’s appearance with consistent use, others may not experience significant changes. It’s also important to note that anti-aging creams are most effective when used as part of a comprehensive skincare regimen that includes sun protection, proper hydration, a healthy diet, and regular exercise.”
Q: How do you apply anti-wrinkle cream?
A: Take a pea-sized amount of cream, and apply it to your cheeks, forehead, and neck zones. Dab it smoothly one hand after another, starting from the face’s center, towards the exterior.
Make sure the hand motions on the wrinkly areas are smooth but firm. This self-massage technique ensures that anti-wrinkle cream completely penetrates the skin and also helps further prevent and treat fine lines and wrinkles.
Q: How long does it take for a wrinkle cream to work?
A: Regular use of the product takes three to six months to show noticeable results, and the best results take six to 12 months. As the anti-wrinkle creams contain retinoids which have the potential to cause skin irritation and dryness, doctors and dermatologists recommend applying retinoids every other day at first and gradually moving up to nightly use as necessary.
8 Sources
Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
[1] Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics: https://pmc.ncbi.nlm.nih.gov/articles/PMC8824545/
[2] Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects: https://www.sciencedirect.com/science/article/abs/pii/S014181301833770X
[3] How Much Do We Really Know About Our Favorite Cosmeceutical Ingredients?: https://pmc.ncbi.nlm.nih.gov/articles/PMC2921764/
[4] Moisturizers: Do they work?https://www.health.harvard.edu/staying-healthy/moisturizers-do-they-work
[5] Sunscreen and prevention of skin aging: a randomized trial: https://pubmed.ncbi.nlm.nih.gov/23732711/
[6] Skin anti-aging strategies: https://pmc.ncbi.nlm.nih.gov/articles/PMC3583892/
[7] Dermatologist-recommended skin care for your 20s: https://www.aad.org/public/everyday-care/skin-care-basics/care/skin-care-in-your-20s
[8] Sunscreen and prevention of skin aging: a randomized trial: https://pubmed.ncbi.nlm.nih.gov/23732711/
Was This Article Helpful ?
Yes- No
Health Insiders Team
The Health Insiders Team takes pride in bringing you the latest in nutritional research, skincare, healthy living, and wellness hacks. [Read Full Bio]
Brittany Ferri, MS, OTRL, CLT
See
Our Editorial Process
Meet
Our Review Board
This article changed my life!
This article was informative.
I have a medical question.
Ask a Question
This article contains incorrect information.
This article doesn’t have the information I’m looking for.