Apoaequorin is a protein that is extracted from a type of glowing jellyfish. When apoaequorin is exposed to calcium, protein and calcium bind, creating a bluish light. Therefore, scientists have used apoaequorin to study the properties of calcium.
The synthetic version is added to nootropic supplements because it’s considered to improve memory and mental functioning. In addition, it can enhance the quality of your sleep.
One of the top companies that makes apoaequorin is ‘Quincy Bioscience’ and the product is called Prevagen.
Apoaequorin Ingredients – What to Look For?
This is not a supplement, it’s an individual ingredient. This substance is derived from a jellyfish. Apoaequorin is a protein that’s found inside the Aequorea Victoria species of jellyfish.
How Does It Work | The Science Behind Apoaequorin
Researchers believe that calcium regulation in the brain may play a role in preventing mental decline and improve memory.
According to the American Pharmacists Association, apoaequorin most likely will not be absorbed, instead, it will separate into individual proteins called amino acids . Once separated into amino acids, the body will use them the same as the amino acids from food sources.
In 2017, the Federal Trade Commission (FTC) filed a complaint with the company “Quincy Bioscience” because there was reason the company may have false advertising claims .
Currently, there is insufficient evidence to recommend apoaequorin for amyotrophic lateral sclerosis (ALS, Lou Gehrg’s disease), to increase mental function and other conditions.
A company-sponsored study called the Madison Memory Study tested the product for its effectiveness. The study had 218 participants between the ages of 40-91 years who had memory problems. The results of the study showed improvements in memory among participants.
Although, the research study report had many issues and non-standardized assessment techniques were used.
Apoaequorin Pros & Cons
- Apoaequorin may improve the quality of your sleep and can help your memory.
- There’s not enough evidence to determine correct dosing yet.
- It may lead to mild side effects like nausea, dizziness, or headaches.
- Apoaequorin could occasionally lead to heart or nervous system complications.
- There is little evidence that this product will improve mental function
- Other side effects could a seizures or strokes
Consumer Questions and Answers
Apoaequorin is included in some nootropic supplements. As far as the dosing is concerned, there hasn't been enough scientific research done yet on this substance to know exactly what the dosing should be.
This substance may cause mild side effects such as nausea, dizziness, or migraine headache. Less commonly, users have experienced anxiety, memory issues, and difficulty sleeping. In a very small number of cases this substance has led to heart or nervous system problems.
There are no specific health conditions that preclude taking this substance, except being pregnant or breastfeeding.
It may have some limited benefit, but it doesn't appear to work very well. Most users mentioned that even after months of use, there was no difference in their thinking or memory skills.
This is an ingredient, not a supplement, but it is included in many nootropic supplements. You'd have to find some of these supplements and compare prices and return policies.
|Relief Factor Calm||$21.95||Passionflower, Phosphatidylserine|
|Neuriva||$44.99||Coffee Fruit Extract, Phosphatidylserine|
|Cerebra||$49.95||Citicoline, Bacopa Monnieri, Phosphatidylserine|
|NooCube||$39.99||Bacopa Monnieri, Alpha GPC, Cat’s Claw, L-Tyrosine & L-Theanine|
|Zenith Brain C-13||$39||Huperzine A, DMAE, Rosemary leaf, rhodiola root, turmeric, gingko leaf,|
|Nootrogen||$29.95||Dimethylaminoethanol, Glutamic Acid, L-Tyrosine, Bacopa Extract, Vitamin B3 (niacin)|
|Neuronol||$52.95||Caffeine, L-Glutamine, Taurine, Bacopa Monnieri, Gingko Biloba, Acetyl L-Carnitine, DMAE|
|Dynamic Brain||$43.95||Huperzine A, Bacopa Monnieri, Choline, Phosphatidylserine, Grape Seed Extract, Cinnamon Bark, Olive Leaf, L-Tyrosine|
The price of the apoaequorin will depend on the brand. In this case, it’s relatively inexpensive, about mid-range in the market.
None of the other brain supplements include the ingredient apoaequorin, which is quite telling. It’s obviously not considered all that great a brain health substance.
Is It Safe? – Warnings & Complaints
When ingested orally, this ingredient is fairly safe. It has only been studied for safety for a period of 90 days. Further research is needed to study safety for long-term use.
Apoaequorin Customer Reviews & Results
Overall, reviews about this substance have been more negative than positive. The consensus seems to be that even after months of use, it has very little effect on memory or general cognitive functioning for the majority of customers.
Apoaequorin: Packages, Deals, Prices & Where to Buy It
This is an ingredient, not a product in and of itself. You’d have to look for supplements that include apoaequorin and compare prices.
The Bottom Line
The only research available is from small company-sponsored trials that do not meet scientific standards. More research is needed to determine the effectiveness of this product.
In reality, looking at reviews of products, it doesn’t seem to work well. There are more negative than positive reviews.
Is There Anything Else You Should Know About Apoaequorin?
Taking a substance or supplement for cognitive enhancement may help improve your memory and mental functioning. This could be especially helpful if you’re experiencing some kind of mental decline.
However, there are also some natural things you can do to improve your brain health.
- Eat nutrient-rich foods with lots of vitamins and minerals. Eat more fruits and vegetables, adequate-protein, and reduce your fat and carbohydrate intake.
- Try to keep in excellent physical condition. Exercise for at least 150 minutes per week or 75 minutes per week of vigorous activity.
- Keep your brain active by reading, doing puzzles, and working on problem-solving tasks.
- Make sure you get an adequate amount of quality sleep every night.
 Apoaequorin | Alzheimer's Drug Discovery Foundation https://www.alzdiscovery.org/assets/content/addf_access/addf-apoaequorin-full-report.pdf