7 sources
Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
[1] Fox BA, Stephens MM. Glucosamine hydrochloride for the treatment of osteoarthritis symptoms. Clin Interv Aging. 2007;2(4):599-604. doi:10.2147/cia.s1632
[2] Henrotin Y, Mobasheri A, Marty M. Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?. Arthritis Res Ther. 2012;14(1):201. Published 2012 Jan 30. doi:10.1186/ar3657
[3] Henrotin Y, Chevalier X, Herrero-Beaumont G, et al. Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities. BMC Res Notes. 2013;6:115. Published 2013 Mar 26. doi:10.1186/1756-0500-6-115
[4] Henrotin Y, Mathy M, Sanchez C, Lambert C. Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations. Ther Adv Musculoskelet Dis. 2010;2(6):335-348. doi:10.1177/1759720X10383076
[5] Bishnoi M, Jain A, Hurkat P, Jain SK. Chondroitin sulphate: a focus on osteoarthritis. Glycoconj J. 2016 Oct;33(5):693-705. doi: 10.1007/s10719-016-9665-3. Epub 2016 May 19. PMID: 27194526.
[6] Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017;9(3):290. Published 2017 Mar 16. doi:10.3390/nu9030290
[7] Brien S, Prescott P, Lewith G. Meta-analysis of the related nutritional supplements dimethyl sulfoxide and methylsulfonylmethane in the treatment of osteoarthritis of the knee. Evid Based Complement Alternat Med. 2011;2011:528403. doi:10.1093/ecam/nep045








This article changed my life!
This article was informative.
I have a medical question.
Ask a Question
This article contains incorrect information.
This article doesn’t have the information I’m looking for.
Triple Flex Reviews
Been taking another brand of joint supplement for years but had to change when we could no longer find that brand. Switched to Triple Flex and it is a great supplement. Triple Flex capsules helped with my stiff joints relief.