
Best Supplements to Reduce Cortisol Review – Health Insiders Images
Highlights
- Purpose: Highlights natural supplements that help lower cortisol—the body’s primary stress hormone—and support overall stress response.
- Key Ingredients: Discusses research-backed options like ashwagandha, phosphatidylserine, Rhodiola Rosea, L-theanine, and magnesium.
- Benefits Covered: Emphasizes improvements in stress resilience, mental clarity, sleep quality, and reduced anxiety.
- How to Choose: Offers tips on selecting high-quality, clinically dosed products for effective cortisol support.
- Usage Insights: Shares guidance on dosage, timing, and combining supplements with healthy lifestyle habits.
Overview
Cortisol is your body’s natural reaction to stressful situations. It can help power you through physically demanding situations and help regulate essential bodily functions. However, when cortisol levels get too high, it can have negative repercussions on your health.
Having consistently high cortisol levels can lead to weight gain, disruptions in your sleep cycle, and work against any weight loss measures you may be taking. So, what can be done about high cortisol levels?
Cortisol reduction supplements have arisen over the past decade or so as a reliable, effective, and practical solution for elevated cortisol levels. In the following article, we will highlight the very best cortisol-reducing supplements currently on the market.
What is Cortisol?
Cortisol is a hormone produced by the adrenal glands, which are located right above your kidneys. It’s commonly known as the “stress hormone” because your body pumps out more of it when you’re stressed, but its role goes well beyond just handling a rough workday or a near-miss in traffic.
Important Physiological Actions of Cortisol are:
Controlling metabolism: Cortisol ensures that your body can break down the proteins, fats and carbohydrates into usable energy, so you have what you need during a stressful situation.
Regulating blood sugar levels: It balances blood sugar levels by enhancing the production of glucose particularly when you require a boost to energy levels.
Modulating immune response: Cortisol possesses an anti-inflammatory effect and assists in regulating your immune system so that it does not get overactive.
Regulating the blood pressure: Cortisol also regulates blood pressure by affecting the fluid balance and vascular tone.
Responding to stress: A key component of the so-called fight or flight reaction, cortisol gets the body ready to deal with threats, actual and metaphorical.
In moderate, controlled doses, cortisol is important to health-but when chronically elevated (as a result of chronic stress, medical issues, or impaired sleep), cortisol may have more of a negative impact than a positive impact, prompting many people to seek ways of managing their levels.
How We Researched and Selected the Best Supplements to Reduce Cortisol?
To compile the following list of the best supplements to reduce cortisol in 2025, we took several factors into consideration. The most important of which were the overall effectiveness of the product, the ingredient quality, scientific backing, and how real users have responded.
Our in-house team of supplement, health, and wellness experts then spent hours poring through reviews, case studies, and clinical trials to identify the supplements that met all or at least most of our criteria. Here are some of the more specific criteria we used to choose the best supplements for cortisol reduction:
- Value for Money – If a supplement was effective for most users who tried it, we deemed it to have high value. Only the highest-value cortisol supplements made our list.
- Clinical Evidence – The ingredients of all the supplements we researched were meticulously scrutinized to ensure that no fillers or dangerous substances were included. Furthermore, we chose supplements with the ingredients that had the best scientific backing.
- Potency and Safety – We didn’t just look at cortisol supplements that were mildly effective. We chose the ones that could make a significant impact for users who need to lower their cortisol considerably. Then, we looked at safety and manufacturing certifications, possible contraindications, and consumer feedback regarding the safety of each supplement.
According to Dr. Firuza Aliyeva, Board-Certified Child and Adolescent Psychiatrist “The best way to lower cortisol naturally is to make certain lifestyle changes, such as getting enough sleep and eating a whole-foods, plant-focused diet, but there is research to suggest certain supplements can also help.”
Our Top Picks
Best Ashwagandha Supplement to Reduce Cortisol: WOWMD Ashwagandha Extra Strength Formula
Best Superfood for Stress and Vitality: WOWMD Greens Blend
Best Supplement for Stress Relief and Mental Clarity: WOWMD Anxiety Shield
Best Supplement to Regulate Cortisol: PrimeGENIX CortiSync
Best Supplements to Lower Cortisol in Women: Gluta Raise
Best Cortisol Reducing Supplement for Men Over 45: TestoChews
Best Cortisol Reducing Supplement for Men Over 40: TestoGreens
Best Rated Cortisol Reducing Supplement: Integrative Therapeutics Cortisol Manager
Best Supplement to Lower the Cortisol: Relacore
Experts Who Contributed
Best Supplements to Reduce Cortisol In 2025
WOWMD Ashwagandha Extra Strength Formula – Best Ashwagandha Supplement to Reduce Cortisol

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.9/5
- Effectiveness 4.9/5
- Convenience 4.9/5
- Value 4.8/5
WOWMD Ashwagandha Extra Strength Formula is a powerful supplement designed to help reduce cortisol levels and support overall well-being. This formula combines organic Ashwagandha root with organic Black Pepper fruit to enhance absorption, promoting stress relief, better mood, and improved mental clarity. As an adaptogen, it helps regulate the body’s stress response, making it an excellent choice for those looking to manage cortisol and improve overall vitality.
Key Specs
- Form: Capsule
- Type: Supplement
- Brand: WOWMD
- Benefit: Reduces cortisol, promotes stress resilience, enhances cognitive function, improves mood
- Active Ingredients: Organic Ashwagandha Root, Organic Black Pepper Fruit
- Dosage: Take 2 capsules daily with water, preferably during a meal
- Price: $57.60*
Pros & Cons of WOWMD Ashwagandha Extra Strength Formula
Pros
- Supports natural cortisol regulation and stress adaptation
- Helps to enhance mood and emotional balance
- Helps to improve cognitive function and mental clarity
- Promotes better sleep quality and sustained energy
- Made with organic, high-quality ingredients
- No artificial flavors or gluten
Cons
- Results may vary based on individual response
- Available for online purchase only
WOWMD Ashwagandha Extra Strength Formula Customer Reviews
Calm and relaxed every day
I take these at night and feel way less stressed during the day. My mind doesn’t race as much, and I’m able to chill out easier. Definitely helps me stay calm. – Kaitlin C.
Feeling Calmer and More in Control
I feel a lot more at ease since taking these. My mind isn’t racing as much, and I handle stress better. No weird side effects, and it feels natural. Definitely sticking with it.– Herman
Summary: WOWMD Ashwagandha Extra Strength Formula is a top choice for reducing cortisol levels naturally. Customers report feeling calmer, more focused, and experiencing better sleep. With its stress-relieving properties and cognitive benefits, it helps improve mood, mental clarity, and overall well-being, making it a great addition to our “Best Supplements to Reduce Cortisol” list.
WOWMD Ashwagandha Review: My Focus, Sleep & Stress Relief Secret (WATCH NOW!) | Video Credit: WOWMD YouTube Channel
WOWMD Greens Blend – Best Superfood for Stress and Vitality

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.9/5
- Effectiveness 4.9/5
- Convenience 4.8/5
- Value 4.9/5
WOWMD Greens Blend combines nutrient-rich organic greens with the calming benefits of Ashwagandha to support overall well-being. Packed with powerful adaptogens, antioxidants, and digestive aids, it helps reduce stress, enhance mental clarity, and boost energy. Perfect for those looking to reduce cortisol and improve vitality.
Key Specs
- Form: Powder
- Type: Supplement
- Brand: WOWMD
- Benefit: Reduces stress, boosts energy, supports digestion, promotes overall wellness
- Active Ingredients: Organic Ashwagandha, Wheatgrass, Spirulina, Chlorella, Organic Greens
- Dosage: 1 scoop (5.4g) mixed with water or smoothie, once daily
- Price: $53.10*
Pros & Cons of WOWMD Greens Blend
Pros
- Supports stress reduction and mental clarity
- Helps to boost energy level and physical endurance
- Promotes digestive health and immune support
- Made with organic, non-GMO ingredients
- Gluten-free and vegan-friendly
Cons
- Taste may require adjustment for some users
- Available for online purchase only
- Results can vary depending on individual use
WOWMD Greens Blend Customer Reviews
Balanced Nutrition
Packed with superfoods like spirulina, kale and turmeric, this blend offers everything I need to feel nourished and revitalized daily. – Mia T.
Very Healthy!
I’m very pleased with this purchase. I feel much better on the days I drink it and it gives me a great start to my mornings. The quality is excellent and I haven’t experienced any indigestion.– Nick
Summary: WOWMD Greens Blend is a great choice for those wanting to reduce cortisol and boost energy. Customers have shared that it helps them feel more focused, energized, and calm throughout the day. With its organic greens and stress-relieving Ashwagandha, it supports overall vitality and well-being, making it a valuable addition to the “Best Supplements to Reduce Cortisol” list.
WOWMD Anxiety Shield – Best Supplement for Stress Relief and Mental Clarity

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.9/5
- Effectiveness 4.9/5
- Convenience 4.8/5
- Value 4.9/5
WOWMD Anxiety Shield is an herbal supplement crafted to reduce stress and anxiety naturally. Combining powerful adaptogens like Ashwagandha, Rhodiola, and Bacopa with essential vitamins, this formula helps promote relaxation, improve mood, and support mental clarity. Ideal for those looking to manage cortisol levels and enhance emotional well-being, this supplement helps maintain balance and resilience to daily stress.
Key Specs
- Form: Capsule
- Type: Supplement
- Brand: WOWMD
- Benefit: Reduces stress, promotes relaxation, supports emotional balance and mental clarity
- Active Ingredients: Ashwagandha, Rhodiola, Bacopa, Lemon Balm, Passionflower, GABA, Magnesium
- Dosage: 2 capsules daily, preferably 20-30 minutes before a meal
- Price: $55.80*
Pros & Cons of WOWMD Anxiety Shield
Pros
- Helps to reduce stress and promotes a calm and balanced mood
- Helps to enhance mental clarity and focus
- Supports emotional balance and well-being
- Contains premium adaptogenic herbs and calming botanicals
- Gluten-free and non-GMO
Cons
- Results can vary based on individual use
- Available for online purchase only
WOWMD Anxiety Shield Customer Reviews
Natural way to relax
Helps me stay calm and handle stress better. Works well for my husband too. Happy to have found this! – Julie H.
Natural way to ease stress
Feels like my stress is finally under control. I’m way more relaxed now, and it’s all natural. It’s working great, so I’ll keep using it. – Rogers C.
Summary: WOWMD Anxiety Shield is a powerful supplement designed to reduce stress and anxiety naturally. Customers have shared that it helps them stay calm, clear-headed, and balanced throughout the day, making it a trusted choice for promoting mental well-being.
PrimeGENIX CortiSync – Best Supplement to Reduce Cortisol

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.8/5
- Effectiveness 4.8/5
- Convenience 4.7/5
- Value 4.7/5
CortiSync is a 100% natural cortisol-reducing supplement designed to support mental clarity, reduce fatigue, and boost energy. Packed with scientifically backed adaptogens like Sensoril Ashwagandha, Rhodiola, and Holy Basil, it helps lower stress levels without requiring changes to your daily routine. CortiSync is the ideal supplement for those struggling with high cortisol levels, offering a simple and effective solution.
Key Specs
- Form: Capsule
- Type: Supplement
- Brand: PrimeGENIX
- Benefit: Reduces cortisol, enhances focus, boosts energy, improves sleep quality
- Active Ingredients: Sensoril Ashwagandha, Rhodiola, L-Theanine, Lemon Balm, Magnolia, Holy Basil, Lichi
- Dosage: 2 capsules daily with a meal
- Price: $59.00*
Pros & Cons of PrimeGENIX CortiSync
Pros
- Helps to reduce cortisol and overall stress
- Boosts energy and improves sleep quality
- Enhances mental clarity and focus
- Natural, clinically proven ingredients
- No need for lifestyle changes
Cons
- Available for purchase only online
- Results may vary depending on the individual
PrimeGENIX CortiSync Customer Reviews
Reduced My Stress and Boosted My Energy!
I’ve been using CortiSync for a few weeks, and I’ve noticed a significant reduction in my stress levels. I feel much more energized and focused throughout the day. It’s really helped me feel more balanced and in control without having to make drastic changes to my routine. Highly recommend it! – Kate W.
Better Focus and More Energy Every Day
CortiSync has been a game-changer for me! I feel less stressed and more clear-headed. My energy levels have improved, and I’m getting better sleep at night. It’s amazing how such a simple supplement can make such a big difference in my daily life! – Andrew H.
Summary: CortiSync is a natural and effective solution for reducing cortisol levels, improving mental clarity, and boosting energy. Users report feeling more focused, energized, and less stressed, making it an excellent choice for managing cortisol naturally.
Gluta Raise – Best Supplements to Lower Cortisol in Women

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.7/5
- Effectiveness 4.7/5
- Convenience 4.7/5
- Value 4.8/5
GlutaRaise is a powerful, all-natural formula designed to modulate cortisol levels, helping reduce stress and anxiety, improve energy, and promote healthy weight loss. By incorporating potent ingredients like KSM-66 ashwagandha, L-Cysteine Hydrochloride, and curcumin, it helps manage stress-induced belly fat and enhances mood and well-being. Ideal for women looking to control cortisol release and reduce stress belly.
Key Specs
- Form: Capsule
- Type: Supplement
- Brand: GlutaRaise
- Benefit: Reduces stress, boosts energy, supports weight loss, enhances mood, promotes balance and emotional well-being
- Active Ingredients: KSM-66 Ashwagandha, L-Cysteine Hydrochloride, Curcumin
- Dosage: 2 capsules daily with the first meal
- Price: $59.00*
Pros & Cons of GlutaRaise
Pros
- Helps to modulate cortisol level for stress relief
- Supports weight loss, especially in the belly area
- Helps to boost energy and cognitive performance
- Natural ingredients with proven scientific backing
- Easy-to-take capsules with no bitter aftertaste
Cons
- Requires consistent use for optimal results
- Only available online
GlutaRaise Customer Reviews
Feeling More in Control
I’ve struggled with stress and weight gain for years, but after trying GlutaRaise, I noticed a difference in just a few weeks. My anxiety has reduced, and I’ve been able to manage cravings better. My stress belly is slowly shrinking, and I feel more energetic and balanced. It’s been a great addition to my routine. – Jessica M.
Stress and Cravings Under Control
I was skeptical at first, but after using GlutaRaise for a few weeks, I started seeing improvements. My energy levels are up, and I’m handling stress much better. My cravings have lessened, and I’m noticing changes in my body. It’s helping me stay focused on my health and feel more in control of my stress. – Heather K.
Summary: GlutaRaise is a natural cortisol modulator that helps reduce stress belly, boost energy, and support weight loss. With potent ingredients like ashwagandha and curcumin, it balances cortisol levels to improve overall well-being.
TestoChews – Best Cortisol Reducing Supplement for Men Over 45

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.8/5
- Effectiveness 4.8/5
- Convenience 4.7/5
- Value 4.8/5
TestoChews is a powerful cortisol-lowering gummy supplement specifically designed for men looking to boost testosterone and reduce stress. With ingredients like Withania somnifera, Vitamin D, and Zinc, it helps combat muscle loss, promote fat burning, and support energy levels. Ideal for men over 45, it helps restore youthful vigor and performance.
Key Specs
- Form: Gummy
- Type: Dietary Supplement
- Brand: TestoChews
- Benefit: Reduces cortisol, boosts testosterone, supports muscle growth, improves mood, enhances energy
- Active Ingredients: Withania somnifera (750 mg), Vitamin D, Zinc
- Dosage: 1 gummy before bed
- Price: $52.00*
Pros & Cons of TestoChews
Pros
- Supports cortisol reduction
- Helps to boost testosterone levels naturally
- Helps to enhance muscle mass and burns fat
- Helps to increase energy and stamina
- Easy-to-consume gummy form
- Backed by research
Cons
- Results may take some time to show
- May require consistent use for best effects
- Limited availability
TestoChews Customer Reviews
Feeling More Energized
I’ve been using TestoChews for a month, and I feel more energized and motivated to work out. My muscle tone has improved, and I’m finally losing some of the stubborn belly fat! – Chris T.
It works!
I wasn’t sure about gummies, but these work! I feel more confident and stronger, and my energy is up throughout the day. – David K.
Summary: TestoChews helps reduce cortisol and boost testosterone, supporting muscle growth, fat loss, and energy. With Withania somnifera, Vitamin D, and Zinc, it’s a convenient and effective way for men over 45 to reclaim vitality and youthful energy. Customers report noticeable improvements in strength, mood, and performance with consistent use.
TestoGreens – Best Cortisol Reducing Supplement for Men Over 45

*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
- Comfort 4.8/5
- Effectiveness 4.8/5
- Convenience 4.7/5
- Value 4.8/5
TestoGreens is a powerful greens supplement designed to support men in reducing cortisol levels and boosting testosterone. It combines adaptogenic herbs, energy-boosting mushrooms, and male-specific probiotics to enhance fat burning, improve energy, and increase vitality. Perfect for men over 40, it helps combat the “estrogen loop” and promotes a leaner, more defined physique.
Key Specs
- Form: Powder
- Type: Dietary Supplement
- Brand: TestoGreens
- Benefit: Reduces cortisol, boosts testosterone, supports fat loss, increases energy
- Active Ingredients: Withania somnifera, Maca root, Ashwagandha, Zinc, Vitamin D, Cruciferous vegetables (cauliflower, kale, etc.), Spirulina, Alfalfa
- Dosage: 1 scoop daily, preferably before 10 AM
- Price: $59.00*
Pros & Cons of TestoGreens
Pros
- Supports cortisol reduction and testosterone boost
- Helps to enhance fat burning and muscle definition
- Helps to improve energy and stamina
- High-quality, male-specific formula
- Refreshing berry flavor
- Free from artificial additives
Cons
- Results may take some time for full effect
- Individual results may vary depending on the health condition
TestoGreens Customer Reviews
This stuff really works!
Since I started using TestoGreens, my energy has been through the roof, and I’m finally losing that stubborn belly fat. I also feel much more confident and energized. This stuff really works!! – Peter A.
Great!
This product has been amazing! I’ve noticed more muscle definition and stamina in the gym. Plus, it tastes great! I feel more energized throughout the day. – Scott S.
Summary: TestoGreens is an effective cortisol-reducing supplement that helps men over 40 combat stress, promote fat loss, and increase testosterone. With its powerful combination of adaptogens, herbs, and probiotics, it supports energy, muscle growth, and overall well-being. Customers rave about its impact on energy levels and fat loss, making it a good choice for reducing cortisol and boosting male vitality.
Integrative Therapeutics Cortisol Manager – Best Rated Cortisol Reducing Supplement

Our Rating
- Comfort 3.8/5
- Effectiveness 3.8/5
- Convenience 3.7/5
- Value 3.8/5
Cortisol Manager claims to support cortisol balance and promote relaxation, but its effectiveness may vary. While it contains ingredients like Ashwagandha and L-Theanine, some users report minimal benefits in reducing stress or improving sleep quality. Additionally, the higher price point may not be justified for everyone, especially considering the mixed results of some experience. For those seeking a more reliable solution, it might not be the best fit.
Key Specs
- Form: Tablet
- Type: Supplement
- Brand: Integrative Therapeutics
- Benefit: Supports cortisol balance, relaxation, better sleep, stress management
- Active Ingredients: Sensoril Ashwagandha, L-Theanine, Magnolia Extract, Epimedium Extract, Phosphatidylserine
- Dosage: 1 tablet before bed, increase to 2 tablets during high-stress periods
- Price: $68.50*
- Where to Buy: Amazon
Pros & Cons of Cortisol Manager
Pros
- Supports stress relief and relaxation
- Helps improve sleep quality
- Contains natural, vegan-friendly ingredients
- Good for adrenal health support
Cons
- Mixed results on sleep improvements
- Some users report increased anxiety
- Higher price point compared to similar products
- Not effective for everyone
Cortisol Manager Customer Reviews
Didn’t Work As Expected
I tried Cortisol Manager to help with my stress and sleep, but the results were minimal. While it did make me feel a bit more relaxed, I didn’t notice much improvement in my sleep quality. For the price, I expected better results. – Sam R.
A Little Disappointed
I had high hopes for Cortisol Manager, but after using it for a month, I didn’t see a big difference in my stress levels or sleep. It did help me relax a little, but not enough to justify the cost. – Lisa K.
Summary: Cortisol Manager claims to help with stress and sleep but may not be effective for everyone. Despite containing helpful ingredients like Ashwagandha and L-Theanine, many users report minimal benefits, especially considering its higher price point.
Relacore – Best Supplement to Lower the Cortisol

Our Rating
- Comfort 3.7/5
- Effectiveness 3.7/5
- Convenience 3.7/5
- Value 3.8/5
Relacore is a stress relief and belly fat reduction supplement. It claims to help reduce stress and the associated belly bulge by targeting cortisol levels. While it contains a variety of ingredients that support mood improvement and immune health, results are mixed.
Key Specs
- Form: Tablet
- Type: Supplement
- Brand: Relacore
- Benefit: Stress relief, belly fat reduction, mood improvement, immune support
- Active Ingredients: Vitamin C, Thiamine, Riboflavin, Niacin, Vitamin B6, Biotin, Pantothenic Acid, Calcium, Magnesium, Zinc, Passionflower Powder, Magnolia Powder
- Dosage: 3 tablets per day
- Price: $29.99*
- Where to Buy: Amazon
Pros & Cons of Relacore
Pros
- Supports stress reduction
- May help reduce belly fat
- Provides immune system support
- Improves mood
- Non-sedating
Cons
- Mixed effectiveness
- Some users experience mild side effects (e.g., headaches)
- Results may vary
- Not suitable for everyone
Relacore Customer Reviews
Nope Not For Me
I was on the fence for at least a month about this product after I found it. So between car accident and quitting smoking I gained a bit of weight which also came with anxiety. I started this 06/14/2025 and today 06/27/2025 I’ve had nothing but headaches last few days and anxiety is soooo bad at first it mellowed me out and took care of anxiety etc but it just came back full force. Definitely will not purchase again. – Crystal
Still taking them to see if they going to work all this time
Didn’t work as quickly as used to. – Kathleen Holston
Summary: Relacore Extra may help manage stress for some, but its effectiveness in reducing belly fat is mixed. While a few users notice improvements in mood and energy, others experience little to no change, making it a hit-or-miss option.
How to Choose the Best Cortisol Supplement?
The list provided above will give you a great roadmap for choosing the right cortisol supplement for you. But we always want to ensure that you have all the resources you need to make the healthiest choice for you and your family. So here are some expert tips on how to choose the best cortisol supplements for your specific needs:
- Ingredients – The ingredients of any supplement are its main indicators of quality. You need to choose supplements that have ingredients with proven track records. In the case of cortisol-lowering supplements, you will want to choose one that includes ingredients like ashwagandha, turmeric, moringa, omega-3 fatty acids, rhodiola, and L-theanine. These ingredients have been proven to benefit cortisol regulation in one way or another.
- User Goals – Of course, you will need to choose a product that aligns with your health goals and requirements. Identify the most important health factors to you. For example, you may be experiencing a lack of sleep due to increased cortisol levels. In this case, you may want to choose a supplement that contains ashwagandha, as this herb has been found to benefit sleep quality and cortisol regulation.[1] You should also ask your doctor to help you establish health goals that will benefit your wellness and point you in the right direction of a beneficial supplement.
- Side Effects – Naturally, you don’t want a supplement that poses a high side-effect risk. So keep a lookout for consumer reviews that specifically mention side effects. Be sure to keep in mind any medications or vitamins you may already be taking and make sure that the ingredients of the supplement you are considering do not interact negatively with them.
Health Risks Associated with High Cortisol
High cortisol may have a significant impact on your health. The constant increase of this stress hormone is met with several severe complications:
Increase in weight particularly around the belly area: Cortisol promotes the storage of fat making weight loss not easy and adds weight to the belly area.
High blood pressure: Constant high cortisol may narrow the blood vessels causing high blood pressure.
Osteoporosis: Cortisol also slows the formation of bone and may cause weakened bones, increasing the risk of fractures.
Disrupted blood sugar and diabetes: Over time, high cortisol may hinder insulin effectiveness, increasing the likelihood of developing type 2 diabetes.
Cognitive and mood issues: Poor memory and mood changes, along with an increased risk of dementia in severe cases, are all associated with long-term cortisol imbalance issues.
Other symptoms such as unexplained headaches, changes in sleep pattern, muscle pain or joint pain, gum problems and hormonal imbalances like unwanted hair growth among women may be felt, as well.
Though all these possible problems can seem frightening, the positive points are that many evidence-based solutions are effectively engaged with, including lifestyle changes and carefully studied supplements, which can ensure proper cortisol levels and minimize your risks in the long term.
Do Cortisol Supplements Work?
The answer to this question is both yes and no. A cortisol supplement will not work if it does not contain quality ingredients. However, quality cortisol supplements with ingredients like ashwagandha, omega-3 fatty acids, moringa, and turmeric have all been validated by scientific trials and research.
For instance, the active compound in turmeric has been studied at length for its effect on cortisol levels.[2] The findings strongly suggest that curcumin, the active compound in turmeric, inhibits clinically significant spikes in cortisol. The National Institutes of Health elaborates on these findings in the following study quote:
In the present study, we found that in contrast to its direct stimulatory effect on cortisol production, curcumin inhibited the large increases in cortisol production that are stimulated by ACTH and AngII. Curcumin also inhibited Cav3.2 Ca2+ channels in AZF cells with similar potency.
Common Ingredients in Cortisol Reducing Supplements
In the following section, we will discuss some of the ingredients you should be looking out for when choosing the best cortisol-lowering supplements:

Magnesium
Magnesium supports hormone production by regulating enzymes involved in insulin and cortisol balance. Side effects may include diarrhea with high doses. Interactions with certain medications, like diuretics, can occur.

Ashwagandha
Ashwagandha is another ingredient like turmeric that has potent antioxidant effects. In addition, it has been found to have adaptogenic effects meaning that it can benefit the way your brain manages stress in general. It also helps with sleep as we read in the following Pubmed study quote:[1]
The present study confirms that Ashwagandha root extract can improve sleep quality and can help in managing insomnia. Ashwagandha root extract was well tolerated by all the participants irrespective of their health condition and age.
According to Dr. Ryan Sultan MD “Ashwagandha is a wonderful evidence-backed supplement. Multiple randomized control trials have shown significant reductions in cortisol levels and stress symptoms over 60–90 days at particular doses. It can also improve sleep, which is critical for reducing overall stress levels.”

Turmeric
Turmeric is a yellow spice that contains the compound known as curcumin. Curcumin has incredibly potent antioxidant properties and has been observed to inhibit cortisol secretion in high-stress situations. Additionally, curcumin has been tied to various physiological benefits such as joint health, organ health, and more.[2]

Spirulina
Spirulina has been proven in animal studies to reduce the damage of oxidative stress and lower serum cortisol levels in the blood. The study also suggested that spirulina supplementation could lessen the detrimental effects of the physiological changes that occur when the body and mind are stressed.[3]

Moringa
Moringa is a botanical extract which has been recognized for having valuable antioxidative properties. Clinical trials have linked it to reduced stress levels. Other scientific studies have found that moringa extract is especially helpful for reducing inflammation.[4]

Wheatgrass
Wheatgrass is considered a superfood because it contains a dense combination of key nutrients like vitamins, minerals, phytochemicals, and amino acids. It is beneficial for cortisol regulation because it helps the brain and body manage stress and mitigates some of the effects of free radical cells.[5]
Benefits of Cortisol Supplements
- Better Sleep: Since stress is closely tied to sleep quality, cortisol supplements may provide the added benefit of improved sleep quality by reducing overall sleep latency and allowing the user to reach deeper levels of rest.
- Reduced Mental Fatigue: Stress takes a large toll on your body and your brain. It initiates physiological changes that, when left unchecked, can have serious cognitive repercussions. Cortisol supplements can reduce mental fatigue by improving the way your brain responds to stress.
- Calming Effects: If you are the kind of person that has a hard time winding down after a long day, these supplements can help. Many of them contain ingredients that are known to induce a sense of calm and relaxation.
- Emotional Stability: You aren’t yourself when you are under copious amounts of stress. These supplements may benefit your emotional stability and help you stay on an even keel no matter what your daily routine entails.
- Antioxidant Defense: The supplements on our list contain potent antioxidants that can benefit your physical and mental health by offsetting many of the damaging effects of oxidative stress.
Are Cortisol Supplements Safe to Use?
While supplement products are not regulated by the FDA, the safest cortisol-reducing supplements will have certain certifications that indicate the cleanliness of the ingredients, the quality of the manufacturing process, and the potency of the formula.
Look for Good Manufacturing Practices certifications and clean ingredient certifications when shopping. Most reputable brands will have these and additional safety and health certifications.
Also, be sure to discuss any medications you may be taking with your physician before using cortisol supplements, as they may cause contraindications. While the products on our list have been safe for most users, some may cause mild side effects like headaches, nausea, and abdominal distress.
Who Should Consider Using These Supplements?
Not everyone is in need of a cortisol-lowering supplement. But take a look at the following guidelines to see if you might benefit from using one of these products:
- Chronic Stress – If you experience stress from work, school, familial obligations, interpersonal relationships, or other sources on a near-daily basis, you are a good candidate for cortisol supplements.
- Cognitive Impairment – Elevated cortisol levels can negatively affect the brain’s hippocampus. If you are experiencing trouble concentrating, reduced verbal eloquence, or scattered thoughts, you may need to lower your cortisol levels.
- Obesity – Many people with elevated cortisol levels also exhibit “cortisol belly” or pronounced weight gain. If you have been gaining weight and can’t figure out why, a cortisol supplement may be the solution.
- Poor Sleep – Elevated cortisol can make it difficult to sleep. Taking a proven cortisol supplement may reduce sleep latency and improve your overall sleep quality.
- Unstable Mood – One of the cognitive effects of cortisol spikes is emotional instability. A quality cortisol supplement may help balance your mood.
Practical Habits to Lower Cortisol Naturally
Beyond supplements and clinical interventions, everyday habits can play a powerful role in supporting healthy cortisol levels. Here are a few approachable strategies to fold into your daily routine:
Mindful Movement: Incorporating activities like yoga, tai chi, or even regular stretching can help calm your nervous system and support balanced cortisol.
Meditation and Deep Breathing: Taking a few minutes each day for mindfulness, deep breathing, or guided meditation has been shown in research to reduce stress hormones.
Quality Sleep: Prioritizing restful sleep and maintaining a consistent bedtime can make a meaningful difference in your body’s stress response.
Nature Walks: Getting outside for a walk even if it’s just around the block can help moderate cortisol, with some studies highlighting added benefits when you spend time in green spaces.
Physical Activity: Regular exercise, tailored to your ability and preferences, supports both physical and mental health and helps keep cortisol in check.
Building these habits steadily over time can contribute significantly to keeping stress in balance and promoting overall well-being.
Final Verdict
The products on our list represent the most reliable, safest, and highest-value cortisol supplements on the market. But you are encouraged to refine your selection by speaking with your trusted healthcare practitioner, choosing a supplement with effects that align with your health goals, and by comparing customer reviews of various supplements.
In these ways, you will have a great chance at finding a cortisol supplement that makes a significant positive impact on your metal and physical health.
Our list is a great place to start your research, so be sure to carefully examine each one. Also, take what you have learned in this article to find the best supplements to reduce cortisol for your specific needs.
Best Supplements to Reduce Cortisol – Frequently Asked Questions
Q: What is the best cortisol reducer supplement?
A: WOWMDs Ashwagandha Extra Strength Formula is one of the best because it ticks all the boxes: proven ingredients, safe formulation, great reviews, and it’s made by a reputable manufacturer.
Q: How can I lower my cortisol level quickly?
A: Deep-breathing exercises can help lower your cortisol levels. Also, try engaging in physical activity to provide an immediate outlet for stress.
Q: Which vitamin is good for reducing cortisol levels?
A: Vitamin C may help reduce cortisol levels as it contributes to your body’s overall level of antioxidants.
Q: Does ashwagandha actually reduce cortisol?
A: Ashwagandha not only helps your brain manage stress more effectively, studies have shown that it does actually reduce serum cortisol levels and reduces activity of key hormone receptors.
Q: What is the best way to lower cortisol levels?
A: Slow, relaxed breathing or breathwork has been shown to immediately calm anxiety, regulate heart rate and reduce blood pressure and subsequently decrease cortisol levels in a matter of minutes.
Q: What is the effect of stress on cortisol and weight?
A: The prolonged stress elevates the level of cortisol, which may disturb appetite, metabolism, and fat deposits, primarily in the abdominal area, leading to weight gain and obesity.
Q: What are the effects of exercise on cortisol and sleep?
A: Frequent physical activity lowers the level of cortisol, stress and improves sleep, so it is one of the best ways to maintain normal cortisol and have better sleep.
Q: Can high cortisol cause dementia or Alzheimer’s?
A: High cortisol, often from long-term stress, may harm memory and brain areas, possibly increasing the risk of dementia and Alzheimer’s disease.
5 sources
Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
[1] Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study: https://pubmed.ncbi.nlm.nih.gov/32818573/
[2] Curcumin Inhibits ACTH- and Angiotensin II-Stimulated Cortisol Secretion and Cav3.2 Current: https://pmc.ncbi.nlm.nih.gov/articles/PMC2853174/
[3] The Preventive Role of Spirulina Platensis (Arthrospira Platensis) in Immune and Oxidative Insults in a Stress-induced Rat Model: https://pmc.ncbi.nlm.nih.gov/articles/PMC8256474/
[4] Moringa oleifera: An Updated Comprehensive Review of Its Pharmacological Activities, Ethnomedicinal, Phytopharmaceutical Formulation, Clinical, Phytochemical, and Toxicological Aspects: https://pmc.ncbi.nlm.nih.gov/articles/PMC9916933/
[5] Effect of aqueous extract of barley and wheat grass in stress induced depression in Swiss mice: https://pmc.ncbi.nlm.nih.gov/articles/PMC9468397/
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The Health Insiders Team takes pride in bringing you the latest in nutritional research, skincare, healthy living, and wellness hacks. [Read Full Bio]
