There’s a lot of buzz these days about probiotics. It seems we’re all lacking in these healthy bacteria.
So more of them can only be a good thing.
But is there any value in taking a supplement?
Well, the answer isn’t so easy.
But First, What are Probiotics?
Probiotics are a form of bacteria that benefits your digestive system. There are two types of bacteria in our gut: the good kind and the bad kind. Everybody has both. But the balance of the two is what makes the difference.
Think of the kid’s game ‘cops and robbers’. Some of the bacteria are good guys. And some are bad guys. So the more of the good guys you have, the more they’re able to destroy the bad guys. And the good guys are what we call probiotics. A Study has also presented a document regarding ISAPP’s consensus meeting on the appropriate use and scope of the term “probiotic”.
What You Should Know About CFU in Probiotics
In probiotics, the CFUs are the number of viable bacteria in the probiotic supplement. CFUs are typically measured per milliliter or per gram. A supplement with 5 billion CFUs means it contains 5 billion probiotic bacteria strains. Are high billion count probiotics better that those with lower CFU? Not really, this is somewhat a myth and marketing strategy that brands use as a selling point to attract customers.
Who Benefits The Most From Probiotic Supplements?
The people who benefit the most from probiotic supplements are those who have too many of the robbers – aka ‘the bad bacteria”. When there aren’t enough of the good guys, the bad guys run rampant through your digestive system.
How do you know you have too much bad bacteria?
Well, there are a few significant risk factors for which you want to be aware of. These increase your risk of a bacterial imbalance.
If you’ve taken multiple rounds of antibiotics in your lifetime, you’re at increased risk. This is also the case for women who’ve taken long-term hormonal birth control. And if you’ve eaten a standard Western processed and high-sugar diet, you may also have too many bad guys.
What Foods are Good Sources of Probiotics?
Probiotics can be found in more than just supplements. They can be found in natural whole foods.
What foods are good sources of probiotics?
That would be any fermented food. Things like miso, kombucha, kimchi, kefir, yogurt, sauerkraut, and tempeh. ISRN Nutrition has also cited the beneficial properties of Probiotics focusing on those available in food.
There’s a current trend for food manufacturers to supplement other types of food with beneficial probiotics bacteria. So you’ll now see probiotics in foods that never had them before like ice cream and sports bars. These foods have been enriched with probiotics.
But is getting these healthy bacteria from food enough? Or is taking it in pill form better?[1] Well that really depends on the amount of beneficial bacteria your digestive system needs.
Beneficial Bacteria in Probiotic Supplements
Probiotic supplements offer beneficial bacteria in the billions. So a low dose probiotic may offer one or two billion CFUs. A high dose supplement can offer something like 50, 60, or 70 billion.
Let’s compare that to what you find in fermented foods.[2]
A cup of sauerkraut will contain a few billion CFUs. The same goes for yogurt and miso. You get the idea. We’re dealing with a relatively small dose, which is excellent for people who already have a healthy gut.
But what if you need more?
If you’ve spent good amounts of time on medications, especially antibiotics, the chance goes up that you have a significant bacteria imbalance and you need a higher dose. And this is when a probiotic supplement can be useful.
We usually get bacterial imbalances from unnatural situations: things like high dose medications, high-sugar diets, and lots of stress. So finding everything you need just from whole foods might not work in this situation. This is when a supplement may be the answer.
How We Choose The Best Probiotic Supplements
Our team of experts works hard and is always transparent about the facts of the supplements and why certain supplements are recommended by us. We provide all the reports and information about the supplements that are evidence-based and rooted in science. We place a high value on certain product attributes such as product ingredients, product benefits, as well as research studies and customer reviews to narrow down the best probiotic supplements.
Overview of Our Best Pick of Probiotic Products
- Best for Immune Health: Multi-GI 5
- Best for General Health: Bio Complete 3
- Best for Digestive Health: Complete Probiotic Platinum
- Best for Personalized Probiotic: BalanceMD
- Best for Metabolism: Gundry MD Energy Renew
- Best for Overall Health: ProPlant Complete Shake
- Best for Gut Health: 1MD GutMD
- Best Nutritional Probiotic: Morning Complete by Activated You
- Best for Value: 1MD Enzyme MD
- Best Pre & Probiotic: PrebioThrive
- Best Plant-Based Probiotic: Gundry MD Lectin Shield
- Best for Healthy Gut Lining: Gundry MD Total Restore
- Best for Overall Wellness: Biome MD
- Best Probiotic Blend: Primal Plants
How do you know if you would benefit from probiotic supplements?
Checking with your doctor or alternative health care provider is an excellent place to start. They can help you assess whether this would be a good option. And if you’ve had long-standing symptoms, you can always experiment with a supplement and see if it helps make things better.
Just make sure not to self-diagnose if you’re experiencing new symptoms. Many of the symptoms I listed as possible indications of a bacterial imbalance have a multitude of causes. And while most of them are innocent, occasionally the onset of one of these symptoms could indicate something more serious. That’s why you want to see a doctor first.
So do you need to take a probiotic supplement?
Now you know that the answer depends on you. If you haven’t already start paying attention to your body’s signs and signals. And that will help you know whether supplementing with beneficial bacteria might be the answer.
When it comes to CFUs in probiotics, quality overrides quantity. The strains that can reach the gut alive are superior to those that can’t. So instead of going for the product with super-high billions count, consider the probiotic strain quality. However, we do not mean that you should ignore the billions count altogether. In fact, the best probiotic supplements should have an average of 1 to 10 billion CFUs.
Probiotics with extremely high CFU count may have a negative impact on the digestive tract and users may experience stomach upset. Alternatively, the bacteria may be flushed out of the system without benefiting the digestive tract.
Multi-GI 5

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Immune Health
Multi-GI 5 is a 3-in-1 blend that claims to support digestive system. The Prebiotic blend supplements the body with nutrients to help digest probiotics. On its part, the GI health blend provides the body with nutrients needed to soothe and enhance intestinal lining. Lastly, the probiotic blend increases the number of healthy bacteria in the intestines.
Quick Facts & Specs
- Form:Powder
- Type:Supplement
- Benefit:Helps users easily opt-out of food craving
- Brand:Unify Health Labs
- Active Ingredients:L-Glutamine, Lactobacillus gasseri
- Price:$69.95*
Multi-GI 5 Pros & Cons
Pros
- This product contains both probiotics and prebiotics
- Most of the ingredients have scientific support to prove their effectiveness
- Multi-GI 5 has a strawberry-lemonade that may appeal to most users
Cons
- Product is quite pricey
How to Use:
Mix a scoop of Unify Multi-GI 5 powder in water or tea and take daily. There is no restriction on when to take so you can take when it is most convenient for you.
Morning Complete

*All the prices listed here are as they appear on their websites and are subject to change.
Best Nutritional Probiotic
Morning Complete is a blend that contains prebiotics, probiotics, and essential nutrients. The prebiotic fiber blend works to improve chronic conditions such as obesity, diabetes mellitus, and cancer. As for the cellular function and liver support blend, it claims to relieve anemia and constipation. And the antioxidant blend works to reduce inflammation and restore the balance of healthy bacteria.
Quick Facts & Specs
- Form:Powder
- Type:Supplement
- Benefit:High in probiotics which could ease digestion
- Brand:Activated You
- Active Ingredients:Gymnema sylvestre leaf, Pomegranate peel extract, Probiotic Blend, Aloe Vera
- Price:$49*
Morning Complete Pros & Cons
Pros
- May have digestive benefits
- May reduce harmful bacteria in the gut tract
- Contains antioxidants thus may prevent oxidative damage
Cons
- Aloe Vera in the formula may cause digestive distress such as diarrhea
How to Use:
Mix a scoop of Morning Complete powder in a drink of your choice and take daily. The powder is easy to dissolve so mixing will be easy.
GundryMD PrebioThrive

*All the prices listed here are as they appear on their websites and are subject to change.
Best Pre & Probiotic
GundryMD PrebioThrive
GundryMD PrebioThrive is a digestive restorative supplement works to reduce cravings and enhance satiety. By improving digestion, this supplement supports the balance of the gut bacteria thereby reducing stomach discomforts.
Quick Facts & Specs
- Form:Powder
- Type:Supplement
- Benefit:Ease constipation and gut discomfort
- Brand:GundryMD
- Active Ingredients:Flaxseed, Agave inulin, Galacto-oligosaccharides
- Price:$79*
GundryMD PrebioThrive Pros & Cons
Pros
- May help treat gut conditions such as constipation, IBS, and ulcerative colitis
- May promote the growth of gut bacteria
- May improve regular bowel movements
Cons
- May cause side effects such as stomach upset, stomach cramps, constipation
How to Use:
Mix a scoop of PrebioThrive with water, or smoothie, or any other beverage. A scoop a day is the recommended dosage.
ProPlant Complete Shake

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Overall Health
ProPlant is a probiotic product that is designed to improve gut health, more so, the leaky gut syndrome. This is a condition that compromises the intestinal lining thus letting toxins into the bloodstream. ProPlant claims to prevent this through reinforcing and maintaining the intestinal lining.
Quick Facts & Specs
- Form:Powder
- Type:Supplement
- Benefit:Elevates heart and brain health
- Brand:GundryMD
- Active Ingredients:Hemp Protein, Spirulina, Flaxseed
- Price:$69.95*
ProPlant Complete Shake Pros & Cons
Pros
- May support digestive and immune health
- May improve mood and overall brain function
- May boost energy levels
Cons
- Without a healthy diet, this product may not work
How to Use:
Mix a scoop of ProPlant Complete Shake powder to a glass of water or unsweetened coconut milk. For better results, use on a daily basis.
Primal Plants

*All the prices listed here are as they appear on their websites and are subject to change.
Best Probiotic Blend
Primal Plants is a concoction of four blends, namely: probiotic blend, digestive support blend, metabolic enhancing blend, and superfood greens blend. These blends work synergistically to improve the health of the digestive system.
Quick Facts & Specs
- Form:Powder
- Type:Supplement
- Benefit:Promotes good digestion and reduces gas and bloating; enhances skin health and appearance
- Brand:GundryMD
- Active Ingredients:Bacillus coagulans, Cinnamon bark, Fennel Seed; Green Tea Leaf
- Price:$99*
Primal Plants Pros & Cons
Pros
- May improve digestive health
- May enhance the immune system
- May support heart health
Cons
- Available in only one flavor
How to Use:
Mix a scoop of Gundry MD Primal Plants in water, green tea, or any other beverage of your liking. This product’s flavor is green apple.
Gundry MD Lectin Shield

*All the prices listed here are as they appear on their websites and are subject to change.
Best Plant-Based Probiotic
Gundry MD Lectin Shield is a plant-based supplement that works to support intestinal health, reduce gas and bloating, minimize food cravings, and promote overall digestive health.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Supports intestinal health; helps curb cravings
- Brand:GundryMD
- Active Ingredients:Sodium Alginate, Bladderwrack, Okra Extract
- Price:$79.95*
Gundry MD Lectin Shield Pros & Cons
Pros
- May improve the digestive system
- May protect the gut lining from damage
- May enhance the immune system
Cons
- May cause loss of appetite
How to Use:
The recommended dose is to take 2 capsules daily with two of the largest meals of the day. To help your body adjust to the supplement, it is recommended to start with a lower dose.
Gundry MD Energy Renew

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Gut Health
Energy Renew is a potent formula that works to boost body metabolism. Through its ingredients, this supplement helps to maintain normal metabolism, accelerate energy, and eliminate brain fog.
Quick Facts & Specs
- Form:Powder
- Type:Supplement
- Benefit:Supports a healthy metabolism; promotes alertness and clear thinking
- Brand:GundryMD
- Active Ingredients:D-Ribose, Bladderwrack, Nitric oxide boosters, Beet Root Extract, Acerola
- Price:$79.95*
Gundry MD Energy Renew Pros & Cons
Pros
- May promote cardiovascular health, energy, and vitality
- May boost metabolism thus accelerate weight loss
- May help increase recovery after workouts
Cons
- May cause side effects such as nausea, diarrhea, and headaches
How to Use:
Mix a scoop of Energy Renew powder into 8 fl. oz. of water and take daily. This blend comes in a passionfruit-hibiscus flavor.
Bio Complete 3

*All the prices listed here are as they appear on their websites and are subject to change.
Best for General Health
Gundry MD Bio Complete 3 is a supplement that focuses on enhancing immune health by improving digestive health. The key ingredients in this formula work to ward off infections and viruses.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Improves growth of gut bacteria; supports digestive health
- Brand:GundryMD
- Active Ingredients:CoreBiome™, Sunfiber®, ProDURA, Beet Root Extract, Acerola
- Price:$80*
Gundry MD Bio Complete 3 Pros & Cons
Pros
- May support digestive health
- May increase energy levels
- May support immune health
Cons
- An ingredient like tributyrin lacks adequate human testing
How to Use:Take a capsule twice per day an hour before a meal, preferably before breakfast. For better results, ensure to take the capsules regularly. It is recommended to follow the dosage as directed by the manufacturer.
Gundry MD Total Restore

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Healthy Gut Lining
Total Restore is specially formulated to minimize bloating, bowel irregularity, gas, and fatigue. It also helps to improve energy production and toxic elimination.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Ease bloating and the gas causes stomach discomfort; improves poor eating habits as it reduces cravings
- Brand:GundryMD
- Active Ingredients:L-glutamine , Licorice root extract, Acerola
- Price:$44.95*
Total Restore Pros & Cons
Pros
- May support weight loss
- May promote healthy digestion
- May improve mental focus and clarity
Cons
- Some ingredients may cause allergic reactions
How to Use:
Take 3 capsules daily. You can opt to take all the three capsules with the largest meal of the day or take 1 capsule three times daily (after each meal).
1MD Complete Probiotic Platinum

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Digestive Health
1MD Complete Probiotic Platinum supplies the digestive tract with 51 billion CFUs. These probiotic strains reach the stomach alive, providing the intestines with a diverse microbiota colony.
Quick Facts & Specs
- Form:Pill
- Type:Supplement
- Benefit:Prevents gas, indigestion, and bloating; inhibits toxins from entering the blood
- Brand:1MD Nutrition
- Active Ingredients:Bifidobacterium lactis, Lactobacillus acidophilus, NutraFlora prebiotic fiber
- Price:$40.99*
1MD Complete Probiotic Platinum Pros & Cons
Pros
- May provide gastrointestinal lining support
- May improve nutrient digestion and absorption
- May be safe for sensitive users as it is free from dairy, peanut, wheat, and shellfish
Cons
- May cause unpleasant digestive issues such as gas, bloating, and stomach upset
How to Use:
Take 1 capsule on an empty stomach or between meals. Users with sensitivity concerns can take with a light meal.
1MD EnzymeMD

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Value
lMD EnzymeMD is designed to relieve discomfort associated with indigestion. It contains probiotics and plant-based digestive enzymes to improve digestion.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Support the natural breakdown and absorption of crucial nutrients; neutralizes the production of gas and toxins in the digestive system
- Brand:1MD
- Active Ingredients:Bromelain, Peptidase, Protease, Glucoamylase
- Price:$35.99*
1MD EnzymeMD Pros & Cons
Pros
- May work to reduce occasional indigestion, bloating, and gas after eating
- May support nutrient digestion and absorption
- May contain 18 plant-based digestive enzymes
Cons
- Results may not be as instant as desired
How to Use:
Take 1 to 2 capsules 20 minutes before a meal or as instructed by a healthcare practitioner.
1MD BiomeMD

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Overall Wellness
1MD BiomeMD is a formula that contains probiotics, prebiotics, and CFUs. It works to improve digestive health by reducing oxidative stress.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Reduces chronic immune system stress; Boosts proper digestion and absorption of nutrients
- Brand:1MD
- Active Ingredients:HUM care4U HMO, Bifidobacterium Lactis HN019, Lactobacillus casei
- Price:$34.99*
1MD BiomeMD Pros & Cons
Pros
- May enhance digestion and nutrient absorption
- May promote bowel movements
- May reduce diarrhea and other digestive issues
Cons
- Results may vary from one user to the other
How to Use:
Take 1 capsule once daily with a fiber-rich meal and a full glass of water or as instructed by your doctor.
1MD GutMD

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Gut Health
1MD GutMD is a formula that improves gut health. It contains high-quality probiotics that increase the number of healthy bacteria in your gut. By improving gut health, it also supports general health and wellbeing.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Boosts the immune system function; supports the gastrointestinal movement
- Brand:1MD
- Active Ingredients:Acacia firber, Licorice root, L-Glutamine, Lactobacillus casei, HMO
- Price:$41.99*
1MD GutMD Pros & Cons
Pros
- May support the integrity of the gut lining
- May maintain immune system function
- May promote overall health and wellbeing
Cons
- Users may have to use this supplement for months to see results
How to Use:
Take 3 capsules once daily with a full glass of water on an empty stomach or as recommended by your healthcare provider.
1MD BalanceMD

*All the prices listed here are as they appear on their websites and are subject to change.
Best for Personalized Probiotic
1MD BalanceMD is a probiotic that boasts of 15 billion CFUs. Similar to other probiotics, this product supports digestive health.
Quick Facts & Specs
- Form:Pills
- Type:Supplement
- Benefit:Supports healthy gastrointestinal lining; helps reduce fungal infection in the gut
- Brand:1MD
- Active Ingredients:Oregano Leaf Extract, Cellulase, Aloe vera leaf gel
- Price:$35.99*
1MD BalanceMD Pros & Cons
Pros
- May promote a healthy balance of the vaginal microbiome
- May reduce the levels of environmental stressors in the gut
- May support nutrient digestion and absorption
Cons
- Ingredients like aloe vera could cause digestive distress
How to Use:
Take 2 capsules once daily before a meal or as instructed by the doctor
CAUTION: “Do not take more than the suggested dosage under any circumstances.”
Are there any physical clues that you have an imbalance?
It would be impossible to write down every possible symptom. And symptoms can often mean more than one thing. But some symptoms hint to the fact you may benefit from probiotic supplements.
Here are a few of the symptoms you may experience when you have too much bad bacteria –
- Diarrhea/ Constipation
- Gas/Bloating
- Acid Reflux
- Acne
- Headaches
- Brain Fog
- Exhaustion
Probiotics – Frequently Asked Questions
Q: What are probiotics good for?
A: Probiotics are good bacteria that have multiple benefits including; improving digestive and immune systems, preventing and reducing digestive issues, and minimizing inflammation and allergies.
Q: What do probiotics do?
A: Probiotics work to strike a healthy balance in the body. Harmful bacteria usually knock the body out of balance thus it is up to the good bacteria to restore this balance. Generally, probiotics improve digestion, keep bad bacteria levels in check, support the gut lining, and enhance nutrient absorption.
Q: Do probiotics make you poop?
A: Yes, especially if you are constipated. While probiotics are not laxatives, they help soften stools and increase bowel movements.
Q: Are probiotics good for you?
A: Yes, probiotics are good bacteria that keep the body healthy and functioning properly.
Q: How long does it take for probiotics to work?
A: On average, probiotics can take 2 to 3 weeks for results to be achieved.
Q: Can probiotics cause diarrhea?
A: Yes, in the first days of consumption, probiotics may cause side effects such as diarrhea, flatulence, and bloating.
Q: Can probiotics cause constipation?
A: Apparently, probiotics can also cause constipation in some users.
Q: Do probiotics help with constipation?
A: Yes, probiotics may relieve constipation by increasing bowel movements
Q: Can you take probiotics with antibiotics?
A: Yes, but they should be taken a few hours apart. Probiotics are typically used to restore the gut bacteria balance after antibiotics.
Q: Do probiotics help you lose weight?
A: While probiotics cannot be used as weight loss supplements, they have a positive effect on weight loss. Some Lactobacillus strains are claimed to reduce body fat thus supporting weight loss.
Q: What is the difference between prebiotics and probiotics?
A: Probiotics are good bacteria strains that improve the digestive system environment. Prebiotics, on the other hand, are plant fibers that are used as food by probiotics.
Q: Can you overdose on probiotics?
A: Overdosing on probiotics may not necessarily cause death, but may cause adverse effects such as gas, bloating, and nausea.
Q: How long should you take probiotics?
A: Most probiotic brands suggest that users should use their products for at least a month to achieve results. Long-term use of probiotics may cause major issues.
Q: Do probiotics help with acne?
A: Yes, Probiotic strains such as Lactobacillus acidophilus can reduce acne by targeting factors that contribute to acne formation. These probiotics stimulate the production of ceramides to help restore healthy fats to benefit acne and minimize side effects.
Conclusion
There you have it, these are the best probiotic supplements according to our research. All these probiotics work to improve gut health and immune health after consistent use. Fortunately, the ingredients in this product are evidence-based meaning they may work effectively.
Apart from our review, read more reviews online to settle for the probiotic that is right for you. For better results, ensure to eat healthy and indulge in regular exercise.
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