Total Package Serum Review: Can This All-in-One Formula Really Make Skin Look 10 Years Younger?

Total Package Serum, a topical skincare product from Sun Coast Sciences, is marketed as an all-in-one anti-aging formula for fine lines, wrinkles, sagging, dryness, and dark spots. With acetyl hexapeptide-8, Matrixyl peptides, sodium hyaluronate, and a stable vitamin C derivative, the brand positions the product as a replacement for several separate skincare products and claims it may help users look up to 10 years younger.

However, do the ingredients occur at the same concentrations found in clinical research? Is there any proof that Total Package Serum alone has the same effects as those of Argireline, hyaluronic acid, Matrixyl peptides, or vitamin C? Are there published clinical trials evaluating the complete formula? And how should consumers understand claims such as “Botox in a Bottle,” “dermatologist-level results,” and “look up to 10 years younger”?

Let’s examine Total Package Serum’s formulation, the scientific evidence behind its main ingredients, the claims used in its marketing, and compare it with two more targeted skincare products, Flawless Bloom Vitamin Glow Face Serum and WOWMD® Hyaluronic Acid Serum.

Total Package Serum Ingredient Analysis

Total Package Serum is a blend of five ingredients, which the brand claims to be its key “anti-aging” ingredients.

• Acetyl Hexapeptide-8 (Argireline®)
• Palmitoyl Pentapeptide-4 (Matrixyl®)
• Palmitoyl Tripeptide-38 (Matrixyl® Synthe-6™)
• Sodium Hyaluronate
• Sodium Ascorbyl Phosphate (Stay-C®)

It also contains ingredients to maintain and stabilize the serum such as olive leaf extract, green tea extract, chamomile extract, arginine and shea butter, along with the aloe vera.

However, one of the most impressive ingredients is Acetyl Hexapeptide-8 (Argireline®), which is a peptide that is often touted as a facial cream alternative to Botox. It is designed to smoothen facial lines by affecting the mechanisms of muscle contraction in the face. In a study published in PubMed, a 10% formulation of acetyl hexapeptide-8 was shown to visibly reduce the depth of wrinkles after 30 days.^[1] The scientists also observed that its biological activity was much less than that of botulinum toxin.

However, because Total Package Serum does not reveal the concentration of Argireline, it is hard to compare it to the one found in the formula used in the clinical study. An NIH study also discovered that the acetyl hexapeptide-8 penetration through the outer skin barrier is limited, thus impacting the penetration into the deeper skin layers.^[2]

The formula additionally includes Matrixyl® and Matrixyl® Synthe-6™, peptides typically found in anti-aging skin care products. These ingredients are sold to promote the production of collagen, skin firmness and wrinkle reduction. Although the work has been done to study the biological activity of Matrixyl peptides, much of the percentage information provided by the brands is based on studies conducted by the suppliers, not large scale independent clinical studies. The amount of either peptide isn’t disclosed by the brand, so it’s hard to determine if Total Package Serum has clinically similar doses.

The presence of sodium hyaluronate (salt form of hyaluronic acid) enhances the hydration of the skin. In clinical trials, topical HA has been proven to increase skin moisture and temporarily increase skin smoothness and plumpness.^[3] The results are dependent on molecular weight, concentration and formulation. The brand claims to employ an ultra-low-molecular-weight version for deeper penetration but fails to offer technical and concentration details to support this claim.

Other ingredients in the serum are Sodium Ascorbyl Phosphate (Stay-C®), a stable form of Vitamin C.
An NIH study says that topical vitamin C has been studied for antioxidant protection,brighter looking skin and skin functions related to collagen.^[4] The efficacy of vitamin C products, however, depends significantly on the concentration, formulation and stability of these products. The proportion of sodium ascorbyl phosphate was not given, and therefore it is hard to compare the formula with the ones reported in the literature.

All things considered, the Total Package Serum is a collaboration of several familiar anti-aging ingredients and offers a clear list of ingredients. However, no amounts of its key active ingredients are included and we could not find any published clinical trials for the final “Total Package Serum” formula. More transparency in doses and more research for the specific product would allow for a better evaluation of its anti-aging properties.

Total Package Serum – Health Insiders Images

Scientific Evidence

Total Package Serum promises to enhance fine lines, wrinkles, sagging, dryness, dark spots, firmness, plumpness, and radiance.

Although the individual ingredients have been researched on their own, in our research, the Total Package Serum formula was not found in the published clinical trial.

This difference matters.

Results indicating that a peptide, Vitamin C combination or product with HA will improve a skin function does not necessarily mean that all products with that ingredient will have the same impact. Results depend on:

• Ingredient concentration
• Molecular size and delivery
• Formula stability
• Frequency of use
• Skin type and condition
• Sun exposure
• Use of sunscreen and other skincare products

For example:

A PubMed study shows Acetyl hexapeptide-8 has shown wrinkle-related benefits in a topical study, but the published formula contained a defined 10% concentration that cannot be directly compared with Total Package Serum’s undisclosed amount.^[5]

Research shows hyaluronic acid can be applied to the skin, which can help with hydration and temporarily soften the lines of dehydration, but it does not have the same effect on the structure of the lines.^[6]

Vitamin C topical formulations might help skin brightness, pigmentation and collagen-related processes, but the effectiveness of topical vitamin C formulations varies greatly by vitamin C derivative, concentration, and delivery system.

Research on branded cosmetic peptides is often smaller and less independent than evidence supporting established photoaging treatments such as topical retinoids. Tretinoin remains an evidence-based standard for photoaging, although tolerability can limit its use.^[7]

The science behind Total Package Serum is therefore based primarily on ingredient-level evidence and branded-ingredient studies, rather than published clinical research on the complete commercial product.

Marketing Claims That Need More Context

Total Package Serum uses several strong anti-aging claims across its product page. While the formula contains legitimate cosmetic ingredients, we believe some of the wording extends beyond the product-specific evidence available publicly.

“Look Up to 10 Years Younger”

The brand often implies that Total Package Serum could make you look 10 years younger, and even 10 – 15 years younger in some sections.

An NIH study says skin can appear smoother and more radiant when it is adequately hydrated, and certain ingredients may gradually soften visible wrinkles or discoloration.^[8] However, “10 years younger” is not a standardized clinical measurement.

Lighting, facial expression, photography, other skin care products, makeup and natural variation can all affect customer perceptions and before and after evaluations.

In our opinion, this claim would be more convincing if the company published a controlled finished-product trial using validated wrinkle, elasticity, pigmentation, and hydration measurements.

“Botox in a Bottle”

According to the brand, Argireline is “Botox in a Bottle” and states it functions practically the same as Botox, without injections.

Acetyl hexapeptide-8 was designed around a pathway associated with neurotransmitter release, but published research states that its effect is much less powerful than botulinum toxin.^[9] Topical penetration may also limit how much of the peptide reaches its intended target.

We believe consumers should understand this as promotional language rather than a clinically established equivalence. A topical serum cannot be assumed to produce the same degree, speed, or duration of wrinkle reduction as a medical injectable.

“Replace Your Entire Medicine Cabinet”

Total Package Serum is promoted as a one-step product that may replace multiple skincare products.

The formula includes moisturizing ingredients, antioxidants, brightening ingredients, and cosmetic peptides. It may replace the necessity for a couple of distinct serums for a person with a basic beauty regimen.

It does not provide sun protection, however, and daily broad spectrum sun protection is still one of the most important steps that can be taken to prevent skin aging from the sun. Sunscreen is essential to anti-aging, not an anti-aging serum.

It also may not replace targeted treatments for acne, rosacea, eczema, severe hyperpigmentation, or established photoaging.

In our opinion, “multi-purpose serum” is a more supportable description than a complete replacement for an entire skincare routine.

“Dermatologist-Level Results at Home”

The product page describes Total Package Serum as providing dermatologist-level results through five clinical-strength ingredients.

Some ingredients have clinical research behind them, but the phrase “dermatologist-level results” is difficult to define. Dermatology treatments include prescription retinoids, chemical peels, lasers, injectables, microneedling, and other procedures with very different mechanisms and expected results.

Without a direct clinical comparison, we do not believe the finished serum can be assumed to match professional dermatologic treatments.

“Visible Results in 14 Days”

The brand’s promise indicates by day 14, expected to have more nourished, glowing skin; by day 30, likely to have improved moisture and fine lines; by day 60, firmer-looking skin; and by day 90, skin that looks 10 to 15 years younger.

A PubMed study shows moisturized skin can be seen more visibly within a relatively short time as humectants and emollients can alter the appearance and feel of the skin.^[10] Loss of colour, wrinkles or firmness take longer to change and can differ from one person to another.

We would like to see this timeline supported by a controlled clinical trial of Total Package Serum rather than testimonials or extrapolations from individual ingredient studies.

“Clinically Proven Peptide Percentages”

The brand cites large percentage improvements in collagen production, wrinkle depth, tightening, hydration, and plumpness for individual ingredients.

These figures may come from studies commissioned or supplied by branded-ingredient manufacturers. Even when valid for the tested ingredient formulation, they do not necessarily apply to Total Package Serum unless the commercial product contains the same concentration and delivery system.

Because the active percentages are not disclosed, consumers cannot confirm whether Total Package Serum closely matches the formulas used to generate those numbers.

Our Verdict on the Marketing Claims

Several of Total Package Serum’s claims are based on reasonable skincare concepts. Hyaluronic acid can improve hydration, vitamin C derivatives may support brightness and antioxidant protection, and cosmetic peptides may soften the visible appearance of some wrinkles.

However, in our opinion, claims involving Botox-like results, dermatologist-level effects, replacement of an entire skincare routine, and looking 10 years younger are broader than the finished-product evidence available publicly.

We found no published clinical trial evaluating Total Package Serum itself, and the concentrations of the main active ingredients are not disclosed.

We recommend viewing Total Package Serum as a multi-ingredient moisturizing and anti-aging cosmetic serum that may improve hydration, smoothness, and overall skin appearance with consistent use—not as a proven replacement for Botox, prescription skincare, sunscreen, or professional dermatologic treatment.

Total Package Serum vs. Popular Anti-Aging Serums

Flawless Bloom Vitamin Glow Face Serum

Flawless Bloom Vitamin Glow Face Serum contains niacinamide, vitamin C, vitamin E, panthenol and linoleic acid to support brighter, more even-looking skin, hydration and antioxidant protection. Unlike products that target more than a single skin issue, the formula targets skin tone, reduces the appearance of dark spots and strengthens the skin barrier.

Flawless Bloom Vitamin Glow Face Serum is a more specific and sincere formula for brightening skin care products, when compared to Total Package Serum. Total Package Serum features multiple peptides, hyaluronic acid and a vitamin C derivative that target a variety of signs of aging, whereas Flawless Bloom targets a smaller set of ingredients that are more universally recognized for radiance and hydration.

We believe that this is what makes Flawless Bloom Vitamin Glow Face Serum a more suitable product for consumers who are looking to improve their skin tone, fade discoloration and keep their skin looking healthy. However, if you’re a person who is searching for an anti-aging serum with peptides, Total Package Serum might still be a good choice.

Winner: Flawless Bloom Vitamin Glow Face Serum

WOWMD® Hyaluronic Acid Serum

WOWMD® Hyaluronic Acid Serum features several types of hyaluronic acid, such as sodium hyaluronate crosspolymer, sodium acetylated hyaluronate and hydrolyzed sodium hyaluronate, to offer multi-level hydration. The formula is designed to increase moisturization, promote softness and hydrating wrinkles and to support the natural moisture barrier of the skin.

WOWMD® Hyaluronic Acid Serum is more specific and hydrating than Total Package Serum. Total Package Serum is designed to address a few signs of ageing with peptides and the help of multiple forms of hyaluronic acid, while WOWMD specifically focuses on providing a long-lasting moisturising effect for multiple signs of ageing with a combination of moisture locking ingredients and multiple forms of hyaluronic acid.

For those who primarily want to resolve dry, dehydrated or tight-feeling skin, we believe this is the more powerful choice between the two: WOWMD® Hyaluronic Acid Serum. Those seeking a hydration serum for dedicated hydration might discover that their preferred formulation would offer optimal benefits, while consumers seeking a more comprehensive anti-aging formula may fare better with Total Package Serum.

Winner: WOWMD® Hyaluronic Acid Serum

Pros and Cons of Total Package Serum

• Combines peptides, hyaluronic acid, vitamin C, and botanical extracts
• Complete ingredient list with no hidden proprietary blend
• May help support hydration, softness, brightness, and smoother-looking skin

• Active ingredient concentrations are not disclosed
• No published clinical trial on the finished Total Package Serum formula
• “Botox in a Bottle” and “look 10 years younger” claims appear overstated
• Does not replace daily sunscreen or medically proven treatments
• Percentage-based claims may come from individual branded-ingredient studies
• Contains isopropyl palmitate, which may not suit every acne-prone skin type
• Customer testimonials cannot establish clinical effectiveness

Final Verdict

Total Package Serum is a combination of proven anti-aging ingredients: the peptides Argireline® and Matrixyl®, sodium hyaluronate, and a stable form of vitamin C. These ingredients appear to have a beneficial effect on hydration, smoothness, radiance and the appearance of fine lines when used regularly, based on the research available.

Many of the product’s more impressive claims, however, are based on research into individual ingredients, not published clinical trials of the product as a whole, including its ability to provide “botox-like” effects, dermatologist-level results, or to make users look up to 10 years younger.

In conclusion, Total Package Serum could work well for individuals who are looking for a comprehensive anti-aging formula that combines multiple active ingredients, but it is better used in conjunction with other skincare products, including daily sunscreen, evidence-based treatments, and dermatologic care products, when indicated.