12 Sources
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[1] Bluett RJ, Gamble-George JC, Hermanson DJ, Hartley ND, Marnett LJ, Patel S. Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. Transl Psychiatry. 2014 Jul 8;4(7):e408. doi: 10.1038/tp.2014.53. PMID: 25004388; PMCID: PMC4119220
[2] Scherma M, Masia P, Satta V, Fratta W, Fadda P, Tanda G. Brain activity of anandamide: a rewarding bliss? Acta Pharmacol Sin. 2019 Mar;40(3):309-323. doi: 10.1038/s41401-018-0075-x. Epub 2018 Jul 26. PMID: 30050084; PMCID: PMC6460372
[3] Kesarwani K, Gupta R, Mukerjee A. Bioavailability enhancers of herbal origin: an overview. Asian Pac J Trop Biomed. 2013 Apr;3(4):253-66. doi: 10.1016/S2221-1691(13)60060-X. PMID: 23620848; PMCID: PMC3634921
[4] Janero DR, Makriyannis A. Terpenes and lipids of the endocannabinoid and transient-receptor-potential-channel biosignaling systems. ACS Chem Neurosci. 2014 Nov 19;5(11):1097-106. doi: 10.1021/cn5000875. Epub 2014 Jun 5. PMID: 24866555; PMCID: PMC4948289
[5] Carbone K, Gervasi F. An Updated Review of the Genus Humulus: A Valuable Source of Bioactive Compounds for Health and Disease Prevention. Plants (Basel). 2022 Dec 8;11(24):3434. doi: 10.3390/plants11243434. PMID: 36559547; PMCID: PMC9782902
[6] Chen J, Liu X, Li Z, Qi A, Yao P, Zhou Z, Dong TTX, Tsim KWK. A Review of Dietary Ziziphus jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection. Evid Based Complement Alternat Med. 2017;2017:3019568. doi: 10.1155/2017/3019568. Epub 2017 Jun 7. PMID: 28680447; PMCID: PMC5478819
[7] Papagianni EP, Stevenson CW. Cannabinoid Regulation of Fear and Anxiety: an Update. Curr Psychiatry Rep. 2019 Apr 27;21(6):38. doi: 10.1007/s11920-019-1026-z. PMID: 31030284; PMCID: PMC6486906
[8] Tripathi AK, Ray AK, Mishra SK. Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials. Beni Suef Univ J Basic Appl Sci. 2022;11(1):16. doi: 10.1186/s43088-022-00196-1. Epub 2022 Jan 28. PMID: 35127957; PMCID: PMC8796742
[9] Kyrou I, Christou A, Panagiotakos D, Stefanaki C, Skenderi K, Katsana K, Tsigos C. Effects of a hops (Humulus lupulus L.) dry extract supplement on self-reported depression, anxiety and stress levels in apparently healthy young adults: a randomized, placebo-controlled, double-blind, crossover pilot study. Hormones (Athens). 2017 Apr;16(2):171-180. doi: 10.14310/horm.2002.1738. PMID: 28742505
[10] Nisar MF, Khadim M, Rafiq M, Chen J, Yang Y, Wan CC. Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review. Oxid Med Cell Longev. 2021 Aug 3;2021:2497354. doi: 10.1155/2021/2497354. PMID: 34394824; PMCID: PMC8357497
[11] Ghasemzadeh Rahbardar M, Hosseinzadeh H. Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders. Iran J Basic Med Sci. 2020 Sep;23(9):1100-1112. doi: 10.22038/ijbms.2020.45269.10541. PMID: 32963731; PMCID: PMC7491497
[12] Lu Y, Bao T, Mo J, Ni J, Chen W. Research advances in bioactive components and health benefits of jujube (Ziziphus jujuba Mill.) fruit. J Zhejiang Univ Sci B. 2021 Jun 15;22(6):431-449. doi: 10.1631/jzus.B2000594. PMID: 34128368; PMCID: PMC8214949
A soothing but semi-researched product
I believe that as a stress and anxiety curing supplement, Anandatol has been quite effective in providing a relaxing cure to my frequent mood swings and mental distress. However, the side effects are a bit bothersome plus as far as I have come to know, there’s still more research going on for the product. But you can still very well go for this supplement. I’ve completed a course myself and it is decent.