Winona Review 2025: How Effective Is This Hormone Therapy for Menopause?

Overview

Many women notice changes in their body as they move through their late thirties, forties, and beyond. You might start feeling more tired, gain weight even without changing your diet, or struggle with sleep. Hot flashes, mood shifts, and low energy can also show up, leaving you unsure of what’s really going on.

Most times, these changes are tied to perimenopause or menopause. And while they’re natural stages of life, they can still take a toll on how you feel each day. That’s why more women are looking for safe and simple solutions that can help bring their hormones back into balance.

One option that’s becoming very popular is Winona. Winona is a telehealth service that provides personalized hormone replacement therapy made to ease menopause and perimenopause symptoms. Everything is done online, and treatments are delivered straight to your door.

But how well do Winona treatments actually work? Can they be trusted as a safe option? And what do women who’ve tried them have to share about their experience?

In this review, we’ll answer all these questions and more. We’ll talk about its ingredients, benefits, and what customers think, to help you decide if it’s the right choice for you.

Let’s get started.

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What Is Winona?

Winona is a personalized hormone replacement therapy designed for women going through perimenopause and menopause. It is offered through an online telehealth service, making it easy and private to start treatment from home.

The treatments come in different forms, including body creams, patches, pills, and vaginal creams. Each option uses plant-based bioidentical hormones that are made to closely match the hormones your body naturally produces. This helps restore balance and ease common menopause symptoms like hot flashes, weight gain, mood swings, and poor sleep.

Winona is designed for women of different ages who are beginning to feel changes linked to hormonal shifts. It gives you access to board-certified doctors, personalized treatment plans, and ongoing support. The process is simple, with everything from consultation to delivery handled online.

Winona – Quick Facts & Specs

Buy on Official Website

*All the prices listed here are as they appear on their websites and are subject to change.

Winona is a personalized hormone replacement therapy made to ease menopause and perimenopause symptoms while supporting comfort, sleep, mood, energy, and libido.

• Form:Creams, Patches, Pills
• Type:Hormone Replacement Therapy (HRT)
• Benefit:Supports hormone balance, reduces hot flashes, improves mood, sleep, energy, weight, and libido.
• Brand:Winona
• Price:From $27 to $399, depending on product and plan.
• Used For:Designed to ease menopause symptoms, restore hormone balance, and improve comfort.
• Active Ingredients:Progesterone USP, Estradiol USP, Estriol, DHEA, Viagra.

Pros and Cons of Winona

• Offers real doctor-prescribed hormone replacement therapy tailored to individual needs.
• Multiple options available, including creams, patches, and pills.
• All treatments are made in certified U.S. facilities.
• Unlimited follow-ups with board-certified doctors at no extra cost.
• Discreet packaging and direct delivery for privacy and convenience.
• Flexible subscription plans with the ability to pause or cancel anytime.

• Not all insurance plans cover the cost of treatments.
• Some results may take weeks or months before noticeable improvements.
• Only available through the official Winona website.

How Does Winona Work?

Winona works to restore balance to hormones like estrogen, progesterone, and DHEA, which naturally decline during perimenopause and menopause. These hormonal changes can affect energy, mood, sleep, weight, and libido. By replacing what the body no longer produces at the same levels, Winona helps reduce uncomfortable symptoms and improve general comfort.

The treatments are absorbed through the skin or taken orally, depending on the form chosen. Transdermal options like creams and patches deliver hormones directly into the bloodstream, avoiding first-pass processing through the liver. This allows the body to use smaller amounts effectively. Oral options, such as tablets and capsules, work through digestion, providing another route for hormone support.

This approach is supported by decades of medical research on hormone replacement therapy. For example, an article in the National Center for Biotechnology Information highlights how restoring hormones during menopause can improve sleep quality, reduce hot flashes, and support long-term health.^[1]

Winona Key Ingredients

Winona treatments use plant-based bioidentical hormones and supportive compounds designed to match the natural hormones produced in the female body. These ingredients include:

Progesterone USP – Progesterone is a hormone that helps support sleep, mood stability, and balance in the reproductive system. It also protects the uterine lining and works together with estrogen to reduce menopause symptoms. Low levels are often linked with sleep disruption, anxiety, and irregular cycles.

According to a review in the journal Climacteric, progesterone therapy has been shown to reduce night sweats, hot flashes, and sleep issues in menopausal women. This makes it an important part of Winona’s hormone therapy options.^[2]

Estradiol USP – Estradiol is the strongest form of estrogen and is often reduced during perimenopause and menopause. It helps manage symptoms such as hot flashes, vaginal dryness, and mood changes. Estradiol also supports bone strength and cardiovascular health. Declines in this hormone are linked to discomfort, sleep struggles, and changes in sexual health.

A review in the National Centre for Biotechnology Information noted that estradiol therapy improves quality of life and reduces menopause symptoms in many women, making it a key part of hormone replacement therapy.^[3]

Estriol – Estriol is a weaker form of estrogen, but it plays an important part in supporting vaginal and urinary health. It is often used in vaginal creams to help with dryness, irritation, and discomfort during intimacy. Estriol works by helping the tissues in the vaginal area stay elastic and hydrated.

In a clinical study published in the European Journal of Obstetrics & Gynaecology and Reproductive Biology, estriol was shown to improve local urogenital symptoms while being well tolerated, making it a safe option for targeted therapy.^[4]

DHEA – DHEA is a hormone naturally produced in the adrenal glands. It supports energy levels, sex drive, muscle tone, and overall vitality. During menopause, DHEA levels drop, which can lead to fatigue and reduced libido. Supplementing with DHEA may help restore balance in these areas.

According to a study in Human Reproduction Update, DHEA supplementation improved sexual function, mood, and energy in women with lower hormone levels, making it a strong support ingredient in Winona’s formulations.^[5]

Sildenafil – Sildenafil, the active ingredient in Viagra, is included in Blossom intimacy cream to increase blood flow to sensitive areas. For women, this may lead to greater arousal, sensitivity, and comfort during intimacy. Unlike oral use, the topical application in Blossom is designed for localized support.

Research in Medscape General Medicine has shown that sildenafil can improve genital blood flow in women, supporting arousal and pleasure. In this way, Winona uses it in a targeted form to help improve sexual wellness for women.^[6]

Benefits of Winona

Here are some of the main health benefits women may experience with Winona treatments:

Eases Hot Flashes and Night Sweats: Hormone balance through Winona helps reduce sudden heat episodes and sweating that interrupt comfort and sleep. This can make nights more restful and improve how you feel throughout the day.

Supports Better Sleep: Restoring progesterone and estrogen levels helps regulate natural sleep patterns. Many women notice they fall asleep easier, stay asleep longer, and wake up feeling more refreshed after starting treatment.

Improves Mood and Emotional Balance: Hormonal changes often cause mood swings and irritability. Winona helps stabilize these shifts, making it easier to stay calm, focused, and emotionally balanced in everyday situations.

Promotes Energy and Vitality: Declining hormones can leave women feeling drained. Winona restores levels that support better energy production, helping you stay active, motivated, and more capable of handling daily tasks without constant fatigue.

Supports Weight and Metabolism: Hormonal shifts during menopause often lead to weight gain. Winona treatments help regulate hormones linked to metabolism, making it easier to maintain a healthy weight with a balanced lifestyle.

Restores Libido and Intimacy Comfort: Low estrogen and DHEA levels can affect sex drive and physical comfort. Winona restores hormonal balance, improving desire, arousal, and vaginal comfort, which helps women enjoy intimacy again with greater confidence.

Is Winona Safe to Use?

Winona is considered safe for most women going through perimenopause or menopause. The treatments use plant-based bioidentical hormones designed to match the ones naturally produced in the body. All products are manufactured in certified U.S. facilities under strict safety standards and prescribed only after review by a board-certified doctor.

The treatments are intended for women going through perimenopause or menopause. They should be taken exactly as directed, whether in cream, patch, pill, or capsule form. Skipping doses or adjusting without medical guidance is not recommended.

Women with a history of certain medical conditions should speak with their doctor before starting treatment. Ongoing check-ins ensure continued safety and proper results.

Winona Customer Reviews

Winona is gaining attention as a trusted option for easing menopause and perimenopause symptoms.

Here are some testimonials from women who have used Winona treatments:

Balanced and Comfortable
Since starting Winona cream and DHEA supplements, I have found my periods are lighter again, my hot flashes and night sweats have stopped, and I feel much more balanced. The cream is unscented and goes on easily and soaks in quickly. My doctor visit was thorough and he was quick to respond to my questions and provide guidance for my body. – Carly L.

Better Sleep and Energy
I’ve been on Winona for 3 weeks… I can feel a difference. I don’t wake up 15 times a night with hot flashes. I haven’t noticed any weight loss, BUT today I actually had enough energy to get on the treadmill. I am so happy!!! Before, I barely had any energy to walk up my stairs. And my joint pain has improved. – Leonor C.

No More Hot Flashes
I have been using Winona for about 10 weeks now. My main purpose was to get rid of the hot flashes I was having. I am happy to say that I have had no hot flashes. I am totally blown away that this worked and so fast as well. Thank you so much for making my life a little cooler!!! – Erika M.

How to Use Winona?

Here are a few steps to follow for Winona treatments:

• Use the prescribed form (cream, patch, pill, or capsule) as directed by your doctor.
• Apply creams or patches to clean, dry skin for proper absorption.
• Take oral tablets or capsules with water at the same time each day.
• Do not skip or change doses without consulting your doctor.
• Follow the schedule provided in your patient portal for consistency.
• Store treatments in a cool, dry place and out of direct sunlight.

Winona treatments are prescription-based and should be used exactly as recommended for best results.

​​How Much Does Winona Cost?

Winona offers different treatments at various price points depending on the product and subscription plan.

Here are some of the main options:

• Estrogen Body Cream – $89 per month or $219 for 3 months.
• Estrogen Patch – $149 per month or $399 for 3 months.
• Estrogen Tablets – $54 per month or $129 for 3 months.
• Progesterone Capsules – $39 per month or $99 for 3 months.
• DHEA Supplements – $27 every 3 months.
• Vaginal Estrogen Cream – starting at $89 per month.
• Blossom Intimacy Cream – $79 per order.

All orders are delivered directly to your door with discreet packaging. Winona also allows you to pause or cancel at any time, making the service flexible and convenient.

Where to Buy Winona?

Winona treatments are only available through the official Winona website. This ensures each order goes through a proper medical review and is prescribed by a board-certified doctor.

The website offers secure checkout, discreet shipping, and the option to manage your subscription through the online patient portal. You can also connect with your doctor, request changes to your plan, or pause and cancel your treatments anytime.

Ordering directly from the official site guarantees you receive authentic medications prepared in certified U.S. facilities, along with ongoing medical support.

Final Verdict

Winona is designed for women who want a safe and convenient way to manage perimenopause and menopause symptoms without repeated doctor visits or pharmacy trips. It provides personalized hormone replacement therapy through an easy-to-use telehealth platform, with treatments shipped directly to your home.

Many women report better sleep, fewer hot flashes, improved energy, and restored balance after starting Winona. The service stands out for its professional oversight, discreet packaging, and flexible subscription options. Treatments are made in certified U.S. facilities and reviewed by board-certified doctors, adding trust and reliability.

If you are looking for a supportive, research-driven solution that helps with sleep, mood, energy, and libido during menopause, Winona is an excellent choice.

Frequently Asked Questions