Peptiva Review – Does Peptiva Work or Is It Just A Hype?

Peptiva Probiotic, a dietary supplement, contains natural ingredients that help to balance your gut flora and enhance the health of your digestive system.

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What is Peptiva?

Peptiva or Peptiva Advanced Digestive Relief is a probiotic which is primarily intended to improve the health of your digestive system and balance your gut bacteria. It has a secondary benefit in that it creates a relaxed, calm feeling in users, and leads to restful sleep.

The calm feeling is caused by valerian root, Gamma-aminobutyric acid, and melatonin, so it is best to take Peptiva Probiotic before bedtime.

About The Manufacturer Of Peptiva

The Peptiva brand is behind this probiotic supplement. The brand claims to use natural ingredients. Peptiva offers a couple of different probiotic supplements, including Peptiva Advanced Digestive Relief, Peptiva + Sleep Support, and Peptiva Vegetarian Digestive Enzymes + Prodigest. No detailed information is available about the Official Website.


QUICK FACTS

 

Peptiva Probiotics
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*All the prices listed here are as they appear on their websites and are subject to change.

Quick Facts & Specs

Peptiva

Peptiva or Peptiva Sleep Support, is a clinically validated probiotic that improves digestive health while promoting deep, restful sleep and finally alleviating your discomfort.

  • Form:Capsules
  • Type:Supplements
  • Benefit:Restores balance to your digestive system, stopping uncomfortable symptoms and promoting regularity.
  • Address:Peptiva, 2323 South 3600 West, West Valley City, UT 84119. 1-800-355-6050
  • Brand:Peptiva
  • Uses:Helps fall asleep and get a more restful sleep.
  • Active Ingredients:Gamma-Aminobutyric Acid, valerian root, melatonin
  • Price:$59.99
 

Peptiva Pros & Cons

Pros

  • It may restore balance to your digestive system, stopping uncomfortable symptoms and promoting regularity.
  • Peptiva Sleep Support can help you fall asleep and get a more restful sleep
  • It can reduce your anxiety, making you feel calm and relaxed.

Cons

  • You can only use Peptiva Sleep Support at night because it causes drowsiness (It has a formula without the sleep support ingredients)
  • There is an interaction with antibiotics, antifungals, immunosuppressants and chemotherapeutic agents (reduces the medication’s effectiveness)
  • Peptiva ingredients may cause side effects like dizziness, pruritis, headaches, GI upset, or muscle weakness.
  • The product contains FD&C Red #40 & FD&C Blue #1. The FDA has stated there is not enough evidence to conclude that artificial food dyes are unsafe, but more evidence is needed.

How Does It Work | The Science Behind Probiotics

Probiotics promote healthy gut bacteria and have been known to have many health benefits. Normally, we have a balance of “good” and “bad” bacteria in our digestive system, but sometimes these two bacteria can be imbalanced.

Causes of this imbalance are illnesses, use of antibiotics and a poor diet . Some of the known health benefits include:

  1. Promotes immune system health– probiotics may inhibit the growth of harmful bacteria
  2. Helps or prevents diarrhea- antibiotic induced and traveler’s diarrhea
  3. Improves some mental health conditions, such as anxiety, depression, OCD
  4. Reduces the “bad” cholesterol (LDL cholesterol) and may modestly reduce blood pressure when taken regularly
  5. May decrease the severity of allergies and skin conditions.

Note: The recommended amount of probiotics to take is 1-100 billion CFU’s per day.

Peptiva

Peptiva Review – Health Insiders Images

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*All individuals are unique. Your results can and will vary.

Peptiva Ingredients – What to Look For?

There are 3 primary active ingredients in Peptiva, plus the probiotic matrix. The Peptiva ingredients are listed below along with information about the probiotic matrix.

Note: This label was taken directly from the official website, click here to view.

Peptiva Supplement Label

Figure 1: Peptiva Supplement Label

Peptiva also includes ingredients that are effective and provide sleep support.

They are listed below.

Gamma-Aminobutyric Acid (from PharmaGABA®) 100 mg – This is an inhibitory brain neurotransmitter in the central nervous system. There’s some evidence that it improves cognitive skills. It promotes relaxation and reduces stress.[1]

“GABA allows the body and mind to relax, fall asleep, and sleep soundly all night,” says Michael J. Breus, Ph.D., a clinical psychologist and board-certified sleep specialist.
  • GABA is only found in fermented foods, such as kimchi, miso, tempeh, and fermented milk products, like kefir. For more information about fermented foods, click here. [2]
  • People with certain medical conditions may have lower levels of GABA, these conditions include:
    1. Seizure disorders
    2. Movement disorders, like Parkinson’s disease
    3. ADHD
    4. Anxiety
    5. Panic disorders
    6. Schizophrenia
    7. Mood disorders, such as depression.
  • The effectiveness of GABA is unclear because experts do not know how much of the neurotransmitter reaches the brain when consumed from food or supplements. More evidence is needed.
  • Some studies have revealed that GABA may reduce blood pressure and symptoms of insomnia, but they were small studies and may be outdated.
  • Side effects of GABA may include upset stomach, sleepiness, muscle weakness, and headaches.

Valerian Root Extract 50 mg – This is an herbal substance which comes from a tall plant that grows in the grasslands. Many studies indicate that it’s an effective sleep aid [3].

  • Valerian root is usually dried and used in teas or capsules
  • A study on valerian root showed that the use of the herb caused participants to fall asleep 7 minutes faster and it improved measured sleep. The side effect of valerian root was noted to be similar to the effects of benzodiazepine medications, which are sedatives
  • Another study showed that it lowered the symptoms of insomnia when compared to a placebo group.
  • More studies are needed on Valerian root because the studies mentioned above were small studies and they had high withdrawal rates from participants. In addition, the studies may have used different species of valerian root.
  • Valerian may cause improved sleep for the following reasons:
    1. it increases GABA, a neurotransmitter that promotes sleepiness
    2. inhibits an enzyme that destroys GABA
    3. valerian extract contains GABA
    4. the amino acid glutamine may cross the blood-brain barrier and turn into GABA.
  • Potential side effects: headaches, pruritis (chronic itchy skin), GI disturbances, dizziness.
Peptiva Sleep Support Review

Peptiva Sleep Support Review – Health Insiders Images

Melatonin (immediate-release) 0.75 mg Melatonin (delayed-release) 0.75 mg

  • Melatonin is a hormone that is very involved in the sleep-wake cycle. It’s released when it’s your regular sleep time, and it makes you drowsy.
  • Melatonin is a hormone that is produced in the pineal gland naturally. It plays a large role in moderating your sleep-wake cycle. It’s normally released when it’s bedtime. Anecdotal reports do mention its effectiveness, but the National Sleep Foundation points out that this really isn’t supported by the research [4].
  • Note: Currently, there are no dosing recommendations for melatonin so supplements may cause melatonin levels to reach much higher levels than they would normally reach without supplementation.

What are Probiotics?

Probiotics are live microorganisms (good bacteria) that are found only in fermented foods and supplements.

Peptiva Probiotics FAQs

Q: How to Use Peptiva?
A: Take one capsule of Peptiva Sleep Support every night, about 30 minutes to an hour before you plan to fall asleep. After about half an hour, you should begin to feel sleepy and relaxed.

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*All individuals are unique. Your results can and will vary.

You shouldn’t take this product during the day, as it can make you drowsy.

Q: Is it ok to mix Peptiva Probiotics with the meds I take now?
A: Some medications that may interact with certain probiotics include: antibiotics, and antifungals (such as clotrimazole, ketoconazole, griseofulvin, and nystatin). Please make sure you speak with your doctor before you begin taking it.

Q: Can I Take Peptiva If I Have A Health Condition?
A: The Peptiva manufacturer recommends that if you have any kind of health condition, you should meet with your physician and discuss it before you start taking this product. In addition, there may be a drug interaction between antibiotics and antifungals.

Q: Does Peptiva Work?
A: Whether Peptiva Sleep Support works or not seems to be quite individual, or it differs depending on the physiology of the person taking the supplement.

The Peptiva probiotic reviews differ widely in their reports of effectiveness, with some being sorely disappointed and perceiving no effect and others thinking this is a miracle supplement. You should take the chance and see if it works for you.

Q: Is there Magnesium in Peptiva?
A: List of some other Peptiva ingredients: Hypromellose, microcrystalline cellulose, silica, magnesium stearate, titanium dioxide and carrot concentrate (capsule colour).

Q: Can people with epilepsy take Peptiva Probiotics?
A: Probiotics may be an option for supplementary therapy. Since the use of probiotics is safe, they may contribute to improving seizure control, and therefore the quality of life, in patients with drug-resistant epilepsy. (source: Clinical Trial – Benef Microbes 2018 doi: 10.3920/BM2018.0018)

Q: Can I take 2 pills of Peptiva Sleep Support to help me sleep?
A: The manufacturer recommends taking Peptiva consistently every night to achieve maximum digestive health benefits. (Note: please take only the recommended dosage.) Common side effects of too many probiotics can lead to bloating, gas, and nausea. People at greater risk of dangerous side effects are those with a weakened immune system or serious illness, in which case you should consult a doctor before taking large amounts of probiotics.

Q: Can I take both the Prodigest and Peptiva Sleep Support?
A: Absolutely! Peptiva + Sleep Support can be used with Peptiva Digestive Enzymes + PRODIGEST. Keep in mind that the digestive enzymes formula is taken immediately before your heaviest meal, while our probiotics + sleep support formula is taken before bedtime.

Q: What Is Peptiva Moneyback Guarantee, Return & Refund Policy?
A: The manufacturer of Peptiva is offering a 30-day money-back guarantee for direct orders from their website. If you’re dissatisfied with the product, you can send it back. If you’re in the auto-shipment program, you can send the bottles back even if they’re empty and get your money back. However, if you’ve made a standard shipment, you have to send it back untouched in the original packaging to get your refund.

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*All individuals are unique. Your results can and will vary.

From a third-party website, the return policy varies depending on the company. Make sure you check it and make sure it meets your needs before you make the purchase.

Q: Please tell me how I can stop my subscription. I just discovered that I cannot take Peptiva pills with my elevated blood pressure.
A: If you signed up for a free trial of Peptiva (at the Peptiva website; NOT Amazon) that automatically enrolled you in auto-ship, and your credit card* will be billed the real amount due (for Peptiva + shipping), monthly, from then on. It’s only free for a trial of 15 days, and even then, you pay shipping by giving them your *credit card. So contact Peptiva to cancel–in writing.

To cancel future shipments in the Auto-Ship Program, you must call the Customer Service Center at 1-800-355-6050 or email the Peptiva Customer Support Team at [email protected]. You must cancel at least 1 day prior to the date that your next monthly shipment is scheduled to be billed in order to not be billed. Accounts cancelled the day of billing will be presented with an option to void that day’s scheduled shipment.

Also, Truebill can help you cancel your Peptiva subscription. Truebill helps you track subscriptions, monitor for changes, and cancel unwanted bills.

Peptiva Alternatives – Compare with Similar Items

Here is a comparison of some of the top brands of probiotic/sleep aids on the market today:

Brand Price Ingredients
1MD Complete Probiotics Platinum $40.99 Bifidobacterium lactis, Lactobacillus acidophilus, and NutraFlora prebiotic fiber
Peptiva $59.99 Gamma-Aminobutyric Acid, valerian root, melatonin
Urinary Tract Support $46.26 Cranberry Fruit, Bbacillus Subtilis, Myoviridae
Vital Reds $69.95 Green tea, Aronia berries, grape seed extract, mulberry extract, bitter melon extract
Florajen 3 $42.99 Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium lactis
Trubiotics $14.50-20 Lactobacillus acidophilus, Bifidobacterium animalis
Colon Detox Plus $24.80 Aloe Vera, Alfalfa Leaf, Cascara Sagrada, Buckthorn, Rhubarb
Synbiotic 365 $45.00 Thiamin (Vitamin B1), Riboflavin (Vitamin B2), Niacin (Vitamin B3), Pyrodixine HCl (vitamin B6), & Folate (vitamin B9)
ActivatedYou Morning Complete $49 Aloe Vera, Green Tea, Turmeric, Ginger Root, Probiotic Blend, Astralagus, Fennel Seed, Spinach, Broccoli, Kale, Cinnamon Bark
DigestZen TerraZyme $50 Papain, Lactase, Protease, Alpha Galactosidase, Sucrase, Enzyme Blend
Provitalize $49 Turmeric, Lecithin, Curry Leaf, Moringa Leaf, B. Lactis, L. Gasseri, B. Breve, Bioperine

The price of the Peptiva Sleep Support is on the high side, but not the highest price out there for this item.

You can see that the Peptiva ingredients are somewhat unique to the other products, although this may mean that it is missing some helpful substances.

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Is Peptiva Safe? – Warnings & Complaints

The biggest warning and complaint were that Peptiva contains FD& C Red #40 & FD&C Blue #1. There were quite a few customers who said that the capsules either didn’t work for them at all, or they actually kept them awake all night.

In some Peptiva reviews, customers said it caused pimples. Others said they couldn’t keep taking it because it made them tired the next day.

Another warning relates to the offer of a free product sample. In some of the Peptiva reviews, users warn that requesting the 15-day sample gets you on a subscription list, and you’ll immediately be charged the full amount for the next month’s supply.

Peptiva Side Effects – Does Peptiva Have Any Side Effects?

The claim of the manufacturer is that the Peptiva probiotic has no side effects whatsoever and that it’s also suitable for vegetarians. It’s completely free of animal derivatives.

Nonetheless, make sure you show it to your doctor and get approval before you begin taking it.

Note: If you experience any of the Peptiva probiotic side effects, stop taking the supplement immediately*

Peptiva Reviews & Results

Customers who purchased Peptiva Probiotics gave very mixed reports of its success. There were many customers who were delighted with Peptiva, including long-time insomnia sufferers. Similarly, many users said it improved their gut health.

There were numerous users, however, who were extremely dissatisfied with the Peptiva probiotic and claimed that it did nothing for them at all.

Others said it helped them sleep, but they couldn’t keep taking it because it made them tired and groggy all morning the next day. In contrast, some users found that Peptiva Sleep Support actually made their insomnia worse.

Naturally, customers who were aware of it were very upset that the product contains FD& C Red #40 & FD& C Blue #1. Users weren’t clear on why the manufacturer decided to include them.

Peptiva: Packages, Deals, Prices & Where to Buy It

If you purchase Peptiva on the official website, it costs $59.99 plus $4.99 shipping. It’s also available from other online retailers for a similar price, but you may want to look around to see if you can get a bargain.

Right now, you may be able to get a free sample of the Peptiva + Sleep support on their website after paying a nominal shipping fee.

Peptiva Probiotics + Sleep Support – The Bottom Line

The product is hard to know because Peptiva reviews are so widely mixed. There were a lot of customers who were just delighted with the results they got from taking this product.

In some cases, it solved serious cases of insomnia. In addition, many users spoke about how effective this probiotic is at solving digestive issues.

On the other hand, there were many complaints noted in some of the Peptiva reviews. Customers said that it either did nothing, worsened their insomnia, or created pimples. You should check with a doctor before using this product.

Consider carefully that Peptiva Sleep Support contains the substances FD&C Red #40 & FD&C Blue #1, which may have negative health consequences, but more research is needed to determine the side effects of dyes.

We recommend Multi-GI 5 by Unify Health Labs as our top pick because it contains ingredients that help increase the body’s energy, improve weight management, as well as improve gastrointestinal lining function.

Is There Anything Else You Should Know About Peptiva?

Peptiva Sleep Support may well help you sleep and improve your digestion, but there are some other things about it that you should consider.

Some key ideas to keep in mind when taking Peptiva Probiotics include:

  • Some people find that even when they take it at night it still makes them tired the next day. If you have something important the next morning, you might want to skip it.
  • If it doesn’t work for you, that doesn’t mean that other similar products won’t.
  • There are some Peptiva side effects and health warnings, so monitor yourself very carefully while taking the product.
  • Remember that the effect of the supplement is different for different people. Don’t expect a miracle just because someone else says they found one.

5 sources

Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

[1] Hepsomali P, Groeger JA, Nishihira J, Scholey A. Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Front Neurosci. 2020 Sep 17;14:923. doi: 10.3389/fnins.2020.00923. PMID: 33041752; PMCID: PMC7527439.

[2] Sahab NRM, Subroto E, Balia RL, Utama GL. γ-Aminobutyric acid found in fermented foods and beverages: current trends. Heliyon. 2020 Nov 16;6(11):e05526. doi: 10.1016/j.heliyon.2020.e05526. PMID: 33251370; PMCID: PMC7680766.

[3] Valerian: A safe and effective herbal sleep aid? - Mayo Clinic https://www.mayoclinic.org/diseases-conditions/insomnia/expert-answers/valerian/faq-20057875

[4] Melatonin and Sleep https://www.sleepfoundation.org/melatonin

[5] Gómez-Eguílaz M, Ramón-Trapero JL, Pérez-Martínez L, Blanco JR. The beneficial effect of probiotics as a supplementary treatment in drug-resistant epilepsy: a pilot study. Benef Microbes. 2018 Dec 7;9(6):875-881. doi: 10.3920/BM2018.0018. Epub 2018 Sep 10. PMID: 30198325.

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Overall Grade: A+

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Synogut

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#3. Ikigai

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Peptiva Customer Reviews and Complaints

Review this product and share your thoughts with other customers

Average Customer Rating:3.2 
19 Customer Reviews

Rating Snapshot:

Excellent 
5
Great 
3
Average 
4
Poor 
4
Bad 
3
Bottom Line: 48% would recommend it to a friend
    By Mary Donnelly 

    Peptiva has a Positive Effect on my IBS

    I have developed IBS-mixed post-menopause. I read the review on Health Insiders and learned about this product on the internet and decided to give it a try. It took four or five weeks to produce a noticeable effect, but I like it—improved stool. If I forget to take it for a few days, I have IBS flares. I am convinced it works well for me.

    By John Daley 

    Peptiva is highly recommended for weight loss

    Peptiva is one of the few digestive aids I have tried that has measurable effectiveness. Taking it over the holidays helped to manage the usual weight gain. My wife and I are both taking it and seeing positive results, not only for weight management but also for digestive system improvements. Highly recommended.

    By Gretchen Barker 

    Consistent & helpful product

    I have been healthy & have maintained weight loss for several years. Peptiva really helps maintain GI health & weight management.

    By Janice Lajeunesse 

    It was quick acting, highly recommend it!

    I started taking it for the probiotic ingredients, not weight loss. Peptiva probiotics sleep support is keeping my bloating down, making me regular which helps extremely when I have several types of medication for AS. I recommend it and will continue using it.

    By Mary Lou Goddard 

    Recommend it for now so far it’s working

    I find peptiva sleep support sure helps with my sleeping, have not noticed any side effects, my digestion troubles seem to have improved a bit, only been taking about a month now!

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