About Nerium

Nerium, now known as Neora, is a direct sales company that manufactures skin care products and supplements. Their skincare products are mostly anti-aging products, while the supplements are intended to promote skin health and beauty, improve sleep, and boost energy levels.

The company claims to employ a holistic approach when it comes to formulating its products.

In this review, we will only focus on Nerium’s anti-aging formulations. The first products launched by the company were the Age-Defying Night Cream and the Firming Body Contour Cream. More products were added as the years went by. The company describes its formula as “Smart Skincare.”

Nerium Ad Age-Defying Review – Health Insiders Images

Nerium – Quick Facts

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*All the prices listed here are as they appear on their websites and are subject to change.

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Pros And Cons of Nerium

It is made up of ingredients with tried-and-tested anti-aging ingredients.
Helps fade away the signs of aging on the skin.
Claims to nourish the skin and improve skin hydration.
Can restore skin firmness and elasticity.
Helps protect the skin against free-radical induced damage.

Many users find the brand a little bit costlier compared to others.
It may take quite a while for the improvements to become noticeable.
It seems to trigger allergic reactions in some individuals.

How Does It Work? | The Science Behind Nerium

Nerium products contain a blend of skin care staples like antioxidants, peptides, vitamins, and peptide extracts. These ingredients work together to hydrate and nourish the skin, thus promoting and maintaining their health and youthful beauty.

In addition, the antioxidants take care of free radicals and other factors that are known to hasten the aging process.

Nerium Ingredients – The Breakdown

Nerium products are built around a signature ingredient called NAE-8, which is composed of:

Nerium oleander Extract – The brand name Nerium is actually derived from the name of this plant. The extract used in Nerium anti-aging products is a proprietary, patented extract. One of its main functions is to provide antioxidant effects, which help protect the cells against free radical damage and delay the signs of skin aging. It shall help reduce the appearance of fine lines, wrinkles, and other signs of aging in the face. It is also thought to have some antimicrobial properties.

The antioxidant effects were evaluated in the 2012 article^[1] from the Iranian Journal of Pharmaceutical Research and the 2018 article^[2] from Industrial Crops and Products. Meanwhile, the antimicrobial effects were discussed in the 2004 article from the Asian Journal of Plant Sciences and 2007 article^[3] from Ancient Science of Life.

Aloe Vera Extract – A staple not just of anti-aging products, but of skin care products in general due to its numerous benefits: antioxidant, antibacterial, anti-inflammatory, moisturizing, nourishing, and wound-healing properties to name a few. These benefits are discussed in this 2017 review article^[4] from the Journal of Pre-Clinical and Clinical Research, as well as in this more recent systematic review^[5] from the Iranian Journal of Medical Sciences.

Nerium Alternatives

Brand	Price	Active Ingredients
Vibriance Super C Serum	$47	Vitamin E, Hyaluronic Acid, Caffeine, 3-O-Ethyl Ascorbic Acid, Synovea Hr, Konjac Root
Rush Remedy	$98.87	Aloe vera, Fruit extract
Fillerina	$53.75	Hyaluronic Acid, Shea Butter, Vitamin E
Plexaderm	$59.95	Titanium Dioxide, Acetyl hexapeptide-8, hydrolyzed rice protein
InvisiCrepe Body Balm	$60	Niacinamide, DL Lipids, and ribose
Hanacure	$110.00	Lotus Leaf Extract, Green Tea Leaf Extract, Honeysuckle Flower Extract, Ginkgo Biloba Leaf Extract, Nicotynol Dipeptide, Copper Tripeptide
Miami MD Cream	$49	Progeline, Haloxyl, Matrixyl 3000, Eyeliss, Argireline, Acetyl Hexapeptide
Musely	$30-$80	Tretinoin, Hyaluronic Acid, Titanium Dioxide, Cucumber Extract

Is Nerium Safe? – Warnings & Complaints

Despite its reputation for being a highly toxic plant, Nerium oleander is actually used for thousands of years in traditional medicine to treat various health conditions.

*All individuals are unique. Your results can and will vary.

The key to its safety and effectiveness is proper preparation and dosage. The extract incorporated in Nerium products has been proven to be safe for daily use.

Nerium Customer Reviews & Results

Customers who have tried Nerium products have only good things to say about the product. They do admit that the brand is a little more expensive than others, albeit worth it. In fact, it is said that some of the products have reached the so-called cult-favorite status.

SEE ALSO – Cindy Crawford Meaningful Beauty and Instantly Ageless

Nerium: Packages, Deals, Prices & Where to Buy It

Nerium products can be bought from the brand’s official website. They are sold as individual products or sets. Individual products cost anywhere from $38 to $290, with prices reduced if you subscribe to auto-ship.

Meanwhile, their most popular sets include the Cleanse, Correct, and Protect Set for $445 ($305 for auto-ship) and the Advanced Skincare Set for $398 ($549 for auto-ship).

Final Verdict

Most people may find Nerium products expensive and therefore not for everyone. While it’s true that the brand is really more expensive than others, many users are claiming that it’s totally worth the hefty price tag.

After all, the company’s philosophy is to provide effective, long-term skincare benefits. Take this with a grain of salt, though, because when it comes to anti-aging products such as Formulyst, Juvederm, Lacura Q10 or any other product for that matter, they don’t work the same way for all people.

If you are still confused on which particular products to go with, do you own research or consult your dermatologist for some valuable advice.

Is There Anything Else You Should Know About Nerium?

Nerium International was the first company to sell Nerium Age-Defying Night Cream. Nerium International re-branded when they lost the rights to the product through litigation. Nerium International is now Neora and their flagship product is called “Age IQ” which is NOT the original product. The company that sells the original NeriumAD with NAE-8 (oleander and aloe vera) is Agellum. Furthermore, NAE-8 is derived from the Nerium oleander plant and not from the yellow oleander, Thevetia peruviana. Hence, Nerium oleander is not the genus and species involved in the toxicity when one reads of poisoning due to the generic term “oleander”. As such, NAE-8 is recognized to be safe and inert especially with topical administration.

Nerium also uses a few other patented or patent-pending ingredients, which include:

SAL-14® – Composed of Bidens pilosa and Mauritia flexuosa, both of which are potent antioxidants.
SIG-1273® (Optimera Formula) – Developed by a Princeton professor Dr. Jeffrey Stock, it is composed of an organic compound that serves to provide superior antioxidant properties.
SIG-1191 – Also developed by Dr. Stock, it is composed of aloe vera, green tea, hyaluronic acid, and jojoba.
Eco-Veil™ – There’s no information about the components, only that it mimics the skin’s natural barrier, thus protecting it from environmental stress.
PhytoLumina – Composed of a proprietary blend of Alpinia officinarum root extract, Physalis pubescens fruit juice, and Bidens pilosa extract.
IFIL4R® – Composed of white lily and Brazilian ginseng extracts.

Nerium – Frequently Asked Questions

Q: How should I use Nerium?

A: Use Nerium products as you would any other skin care products. For the extract instructions, refer to the label of each product.

Q: Does Nerium have any side effects?

A: Nerium products are not supposed to produce any adverse reactions, unless you have allergies or sensitive skin. In case of unwanted reactions, it is advised that you discontinue using the product right away.

Q: Can I take Nerium if I have a health condition?

A: Nerium is formulated to be safe for everyone, even for those with health problems. However, in case of severe or uncontrolled medical conditions, or when you’re simply in doubt, it is recommended that you consult your health specialist first.

*All individuals are unique. Your results can and will vary.

Q: Does Nerium really work?

A: The key ingredient used in Nerium products is not something that you often hear, hence the doubts whether it truly works or not. Nevertheless, you can be sure that this ingredient works wonders too, as evidenced by a couple of studies and actual reviews from satisfied users.

Q: Does Nerium go out of date?

A: At present, there is no requirement for an expiration date on a skin care brand, but if the product is stored correctly, it should have a two-year shelf life. If it has not been stored properly, please ensure the contents have not changed color, consistency, or smell before applying or selling.

Sandy (Amazon Customer) also answered this question on Amazon, ‘I don’t know. There doesn’t seem to have an expiration date on the bottle. It lasts a long time and I use it every night. It does work!

Q: What Is Nerium money-back guarantee, return, and/or refund policy?

A: Nerium offers an unconditional, money-back guarantee for unsatisfied customers who will return their product within 30-days from the date of purchase.

5 sources

Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

[1] Mohadjerani M. Antioxidant Activity and Total Phenolic Content of Nerium oleander L. Grown in North of Iran. Iran J Pharm Res. 2012 Fall;11(4):1121-6. PMID: 24250545; PMCID: PMC3813149.

[2] İrem Atay Balkan, Hacer Tuğba Doğan, Gökhan Zengin, Nesrin Colak, Faik Ahmet Ayaz, Ahmet Ceyhan Gören, Hasan Kırmızıbekmez, Erdem Yeşilada, Enzyme inhibitory and antioxidant activities of Nerium oleander L. flower extracts and activity guided isolation of the active components, Industrial Crops and Products, Volume 112, 2018, Pages 24-31, ISSN 0926-6690, https://doi.org/10.1016/j.indcrop.2017.10.058.

[3] Phytochemical analysis & Antibacterial activity of Nerium oleander.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330883/pdf/ASL-26-24.pdf

[4] Zagórska-Dziok, M., Furman-Toczek, D., Dudra-Jastrzębska, M., Zygo, K., Stanisławek, A., and Kapka-Skrzypczak, L. (2017). Evaluation of clinical effectiveness of Aloe vera – a review. J Pre Clin Clin Res., 11(1), pp.86-93. https://doi.org/10.26444/jpccr/74577

[5] Hekmatpou D, Mehrabi F, Rahzani K, Aminiyan A. The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review. Iran J Med Sci. 2019 Jan;44(1):1-9. PMID: 30666070; PMCID: PMC6330525.

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The Health Insiders Team takes pride in bringing you the latest in nutritional research, skincare, healthy living, and wellness hacks. Together our researchers... [Read Full Bio]

Reviewed by

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