Apoaequorin Reviews – Things You Really Need To Know

Apoaequorin is a protein and synthetic form of nootropic medications that improve memory and mental functioning while also improving sleep quality.

Our Editor Rating:
3.9
Rating Methodology
Disclosure: Every product is independently selected by our editors. Things you buy through our links may earn Health Insiders a commission. Learn more about our review process here.

Overview

Apoaequorin is a protein that is extracted from a type of glowing jellyfish. When apoaequorin is exposed to calcium, protein and calcium bind, creating a bluish light. Therefore, scientists have used apoaequorin to study the properties of calcium.

The synthetic version is added to nootropic supplements because it’s considered to improve memory and mental functioning. In addition, it can enhance the quality of your sleep.

One of the top companies that make apoaequorin is ‘Quincy Bioscience’ and the product is called Prevagen.

Apoaequorin

Apoaequorin Review – Health Insiders Images

Apoaequorin Pros & Cons

pros icon
  • Apoaequorin may improve the quality of your sleep and can help your memory.
cons icon
  • There’s not enough evidence to determine correct dosing yet.
  • It may lead to mild side effects like nausea, dizziness, or headaches.
  • Apoaequorin could occasionally lead to heart or nervous system complications.
  • There is little evidence that this product will improve mental function
  • Other side effects could a seizures or strokes

How Does It Work | The Science Behind Apoaequorin

Researchers believe that calcium regulation in the brain may play a role in preventing mental decline and improve memory.

There are other studies that indicate that in fact, Apoaequorin is digested in the stomach and never ever gets to the brain.

According to the American Pharmacists Association, apoaequorin most likely will not be absorbed, instead, it will separate into individual proteins called amino acids. Once separated into amino acids, the body will use them the same as the amino acids from food sources.

In 2017, the Federal Trade Commission (FTC) filed a complaint with the company “Quincy Bioscience” because there was reason the company may have false advertising claims.

Currently, there is insufficient evidence to recommend apoaequorin for amyotrophic lateral sclerosis (ALS, Lou Gehrg’s disease), to increase mental function and other conditions.

A company-sponsored study called the Madison Memory Study tested the product for its effectiveness. The study had 218 participants between the ages of 40-91 years who had memory problems. The results of the study showed improvements in memory among participants.

Although, the research study report had many issues and non-standardized assessment techniques were used.

Apoaequorin Ingredients – What to Look For?

This is not a supplement, it’s an individual ingredient. This substance is derived from a jellyfish. Apoaequorin is a protein that’s found inside the Aequorea Victoria species of jellyfish.

Note: In 2012, the Food and Drug Administration (FDA) labeled this product as a drug.

Apoaequorin Alternativess

Brand Price Active Ingredients
Apoaequorin $39.95 apoaequorin
Relief Factor Calm $21.95 Passionflower, Phosphatidylserine
Neuriva $44.99 Coffee Fruit Extract, Phosphatidylserine
Alpha Brain $34.95-$79.95 Bacopa, Toothed Clubmoss, Cat’s Claw, L-Tyrosine, L-Theanine, Oat Straw, L-Leucine, Phosphatidylserine
Cerebra $49.95 Citicoline, Bacopa Monnieri, Phosphatidylserine
Zenith Brain C-13 $39 Huperzine A, DMAE, Rosemary leaf, rhodiola root, turmeric, gingko leaf,
Neuronol $52.95 Caffeine, L-Glutamine, Taurine, Bacopa Monnieri, Gingko Biloba, Acetyl L-Carnitine, DMAE
Dynamic Brain $43.95 Huperzine A, Bacopa Monnieri, Choline, Phosphatidylserine, Grape Seed Extract, Cinnamon Bark, Olive Leaf, L-Tyrosine

The price of the apoaequorin will depend on the brand. In this case, it’s relatively inexpensive, about mid-range in the market.

Advertisement

*All individuals are unique. Your results can and will vary.

None of the other brain supplements include the ingredient apoaequorin, which is quite telling. It’s obviously not considered all that great a brain health substance.

Is It Safe? – Warnings & Complaints

When ingested orally, this ingredient is fairly safe. It has only been studied for safety for a period of 90 days. Further research is needed to study safety for long-term use.

NOTE: You may experience mild side effects like headaches or nausea. Occasionally customers have reported anxiety, memory lapses, or sleeping problems. In very rare cases there are heart or nervous system complications.

Apoaequorin Customer Reviews & Results

Overall, reviews about this substance have been more negative than positive. The consensus seems to be that even after months of use, it has very little effect on memory or general cognitive functioning for the majority of customers.

Apoaequorin: Packages, Deals, Prices & Where to Buy It

This is an ingredient, not a product in and of itself. You’d have to look for supplements that include apoaequorin and compare prices.

Is There Anything Else You Should Know About Apoaequorin?

Taking a substance or supplement for cognitive enhancement may help improve your memory and mental functioning. This could be especially helpful if you’re experiencing some kind of mental decline.

However, there are also some natural things you can do to improve your brain health.

  • Eat nutrient-rich foods with lots of vitamins and minerals. Eat more fruits and vegetables, adequate-protein, and reduce your fat and carbohydrate intake.
  • Try to keep in excellent physical condition. Exercise for at least 150 minutes per week or 75 minutes per week of vigorous activity.
  • Keep your brain active by reading, doing puzzles, and working on problem-solving tasks.
  • Make sure you get an adequate amount of quality sleep every night.

Read NextCognifen and Genbrain

Final Verdict

The only research available is from small company-sponsored trials that do not meet scientific standards. More research is needed to determine the effectiveness of this product.

In reality, looking at reviews of products, it doesn’t seem to work well. There are more negative than positive reviews.

Before you begin taking any supplement like Natrol Cognium, Reviva Brain or Limitless NZT-48, make an appointment with your doctor to discuss whether it’s medically suitable for you.

Apoaequorin – Frequently Asked Questions

Q: How to Use Apoaequorin?

A: Apoaequorin is included in some nootropic supplements. As far as the dosing is concerned, there hasn’t been enough scientific research done yet on this substance to know exactly what the dosing should be.

Q: Does Apoaequorin Have Any Side Effects?

A: This substance may cause mild side effects such as nausea, dizziness, or migraine headache. Less commonly, users have experienced anxiety, memory issues, and difficulty sleeping. In a very small number of cases, this substance has led to heart or nervous system problems.

Advertisement

*All individuals are unique. Your results can and will vary.

Q: Can I Take Apoaequorin If I Have A Health Condition?

S: There are no specific health conditions that preclude taking this substance, except being pregnant or breastfeeding.

Q: Does Apoaequorin Work?

A: It may have some limited benefit, but it doesn’t appear to work very well. Most users mentioned that even after months of use, there was no difference in their thinking or memory skills.

Q: What Is Apoaequorin Moneyback Guarantee, Return & Refund Policy

A: This is an ingredient, not a supplement, but it is included in many nootropic supplements. You’d have to find some of these supplements and compare prices and return policies.

SOURCES

Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

[1] Apoaequorin: Uses, Side Effects, Interactions, Dosage, and Warning | WebMD https://www.webmd.com/vitamins/ai/ingredientmono-1486/apoaequorin

[2] Apoaequorin | Alzheimer's Drug Discovery Foundation https://www.alzdiscovery.org/uploads/addf_access/addf-apoaequorin-full-report.pdf

HealthInsiders Team
Written by

Health Insiders Team

The Health Insiders Team takes pride in bringing you the latest in nutritional research, skincare, healthy living, and wellness hacks. Together our researchers...

Why You Should Trust Us

Our medical advisory board and our research team rank the best memory supplements based on performance, label accuracy, and the efficacy of the ingredients in the products.

Start

Our Top Memory Supplements

Here are our top picks for the most effective memory supplements products currently available in the market, as per our assessment.

Overall Grade: A+

#1. Neuro-Thrive Brain Support

  • Improve Memory Function*
    Support Healthy Weight Loss Strong Evidence
  • Reduces Brain Fog*
    Boosts BAT Levels Strong Evidence
  • Strengthens Focus & Clarity*
    Alleviates Oxidative StressStrong Evidence
  • Improves Mood & Sleep*
    Support Heart & Brain HealthModerate Evidence
Neuro-Thrive Brain Support

Rating Breakdown

  • Ingredients star rating 4 9
  • Effectiveness star rating 4 9
  • Safety star rating 4 9
  • Cost star rating 4 9

Overall Rating

Overall Rating4.9
Overall Grade: A+

#2. Claritox Pro

  • Reduces Dizziness*
    Burns Existing Fat Strong Evidence
  • Improves Cognitive Function*
    Reduces Food Cravings Strong Evidence
  • Enhance Emotional Well-being*
    Revitalizes Energy & MoodModerate Evidence
  • Increase Energy & Vitality*
    Boosts MetabolismStrong Evidence
Claritox Pro

Rating Breakdown

  • Ingredients star rating 4 9
  • Effectiveness star rating 4 9
  • Safety star rating 4 9
  • Cost star rating 4 9

Overall Rating

Overall Rating4.9
Overall Grade: A

#3. Alpha Brain

  • Supports Memory*
    Promotes Weight Loss Strong Evidence.
  • Promotes Sustained Focus*
    Boost Natural Energy Strong Evidence
  • Aids Mental Processing*
    Reduces Gas & BloatingStrong Evidence
  • Supports Healthy Stress*
    Promote Clear Thinking Moderate Evidence
Alpha Brain

Rating Breakdown

  • Ingredients star rating 4 8
  • Effectiveness star rating 4 7
  • Safety star rating 4 7
  • Cost star rating 4 8

Overall Rating

Overall Rating4.8

Apoaequorin Customer Reviews and Complaints

Review this product and share your thoughts with other customers

Average Customer Rating:1.7 
3 Customer Reviews

Rating Snapshot:

Excellent 
0
Great 
0
Average 
0
Poor 
2
Bad 
1
Bottom Line: 0% would recommend it to a friend
X

The "Verified Reviewer" authentication is just one more way that we strive to bring our readers the most accurate and reliable information.

×

Add a YouTube video

Have a Question? Please Tell Us What We Are Missing Here!

Note: Health Insiders isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
X

How helpful was it?

icon This article changed my life!
icon This article was informative.
icon I have a medical question.
icon Ask a Question
X

How helpful was it?

icon This article changed my life!
Change
Your Rating
Note: Health Insiders isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
X

How helpful was it?

icon This article was informative.
Change
Your Rating
Note: Health Insiders isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
X
icon I have a medical question.
Change

We’re unable to offer personal health advice, but we’ve partnered with JustAnswer who offers on-demand doctors to answer your medical questions 24/7. Talk online now with a doctor and get fast 1-on-1 answers from the comfort of your couch.

just answer logo
ASK A DOCTOR NOW

If you’re facing a medical emergency, call your local emergency services immediately, or visit the nearest emergency room or urgent care center.

X

How can we improve it?

icon This article contains incorrect information.
icon This article doesn’t have the information I’m looking for.
icon I have a medical question.
icon Ask a Question
X

How can we improve it?

icon This article contains incorrect information.
Change
Your Rating
Note: Health Insiders isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
X

How can we improve it?

icon This article doesn’t have the information I’m looking for.
Change
Your Rating
Note: Health Insiders isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Your Privacy is important to us.
X
icon I have a medical question.
Change

We’re unable to offer personal health advice, but we’ve partnered with JustAnswer who offers on-demand doctors to answer your medical questions 24/7. Talk online now with a doctor and get fast 1-on-1 answers from the comfort of your couch.

just answer logo
ASK A DOCTOR NOW

If you’re facing a medical emergency, call your local emergency services immediately, or visit the nearest emergency room or urgent care center.

English